Prof Richard Pickersgill

Enzyme-cargo encapsulation peptides bind between tessellating tiles of the bacterial microcompartment shell
Gu S, Bradley-Clarke J, Rose R-S, Warren MJ and Pickersgill RW
Journal of Biological Chemistry, Elsevier vol. 300 (6) 
10-05-2024

Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes
Abbott W, Alber O, Bayer E, Berrin J-G, Boraston A, Brumer H, Brzezinski R, Clarke A, Cobucci-Ponzano B, Cockburn D, Coutinho P, Czjzek M, Dassa B, Davies GJ, Eijsink V, Eklof J, Felice A, Ficko-Blean E, Pincher G, Fontaine T, et al.
Glycobiology vol. 28 (1), 3-8.  
11-10-2017

A review of drug therapy for sporadic fatal insomnia.
Tabaee Damavandi P, Dove MT and Pickersgill RW
Prion vol. 11 (5), 293-299.  
04-10-2017

The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system
Gu S, Vladimir VE, Shaw R, Pickersgill and Garnett JA
Bba - Proteins and Proteomics, Elsevier 
19-07-2017

Introducing Quasi-Optical Terahertz Circular Dichroism Spectroscopy
Qui J, Zeng Y, Pickersgill R, Donnan R, Sushko O and Yang B
2017 XI International Conference on Antenna Theory and Techniques (ICATT)., 26-29.  
01-05-2017

Crystal structure of CobK reveals strand-swapping between Rossmann-fold domains and molecular basis of the reduced precorrin product trap
Gu S, Sushko O, Deery E, Warren MJ and Pickersgill RW
Scientific Reports, Springer Nature vol. 5 (1) 
30-11-2015

Structural insights into the loss of catalytic competence in pectate lyase activity at low pH
Ali S, Søndergaard CR, Teixeira S and Pickersgill RW
Febs Letters, Wiley vol. 589 (21), 3242-3246.  
28-09-2015

Sub-Terahertz Spectroscopy as a Probe for Protein Stability in an Ionic Environment
Sushko O, Qiu J, Dubrovka R, Pickersgill RW and Donnan RS
2015 40th International Conference on Infrared, Millimeter, and Terahertz waves (IRMMW-THz)., 1-2.  
01-08-2015

Structural insights into higher order assembly and function of the bacterial microcompartment protein PduA.
Pang A, Frank S, Brown I, Warren MJ and Pickersgill RW
J Biol Chem vol. 289 (32), 22377-22384.  
08-08-2014

FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR).
Lawrence AD, Taylor SL, Scott A, Rowe ML, Johnson CM, Rigby SEJ, Geeves MA, Pickersgill RW, Howard MJ and Warren MJ
Biosci Rep vol. 34 (4) 
04-07-2014

The structure, function and properties of sirohaem decarboxylase - an enzyme with structural homology to a transcription factor family that is part of the alternative haem biosynthesis pathway
Palmer DJ, Schroeder S, Lawrence AD, Deery E, Lobo SA, Saraiva LM, McLean KJ, Munro AW, Ferguson SJ, Pickersgill RW, Brown DG and Warren MJ
Molecular Microbiology vol. 93 (2), 247-261.  
01-01-2014

The effect of the adaptor protein Isd11 on the quaternary structure of the eukaryotic cysteine desulphurase Nfs1.
Terali K, Beavil RL, Pickersgill RW and van der Giezen M
Biochem Biophys Res Commun vol. 440 (2), 235-240.  
18-10-2013

Crystal structure of the bacterial type II secretion system secretin/pilotin complex
Gu S, Rehman S and Pickersgill RW
Acta Crystallographica Section A: Foundations and advances. vol. 69 (a1), s351-s351.  
25-08-2013

Anatomy of secretin binding to the Dickeya dadantii type II secretion system pilotin.
Rehman S, Gu S, Shevchik VE and Pickersgill RW
Acta Crystallogr D Biol Crystallogr vol. 69 (Pt 8), 1381-1386.  
01-08-2013

Lagrangian dynamics analysis of sub-THz skeletal absorption spectra of amino acids acquired by vector network analysis
DONNAN RS, Pickersgill R, Krauss N, Yang B and Sushko O
Chemical Physics Letters, Elsevier vol. 558, 104-108.  
12-02-2013

Substrate channels revealed in the trimeric Lactobacillus reuteri bacterial microcompartment shell protein PduB.
Pang A, Liang M, Prentice MB and Pickersgill RW
Acta Crystallogr D Biol Crystallogr vol. 68 (Pt 12), 1642-1652.  
01-12-2012

A joint neutron/X-ray crystallographic study on the mechanism of pectate lyase
Ali S, Blakeley M, Søndergaard CR, Pellegrini E, Teixeira SCM and Pickersgill RW
Acta Crystallographica Section A: Foundations and advances. vol. 68 (a1), s91-s91.  
07-08-2012

Solution structure of homology region (HR) domain of type II secretion system.
Gu S, Kelly G, Wang X, Frenkiel T, Shevchik VE and Pickersgill RW
J Biol Chem vol. 287 (12), 9072-9080.  
16-03-2012

Structural and functional insights into the pilotin-secretin complex of the type II secretion system.
Gu S, Rehman S, Wang X, Shevchik VE and Pickersgill RW
Plos Pathog vol. 8 (2) 
01-02-2012

Pathology: A Structural Biologist's View
Pickersgill RW
JOURNAL OF PATHOLOGY. vol. 226, S7-S7.  
01-01-2012

Intestinal Glycogen Storage Disease, and the Molecular Basis of Pseudo-obstruction with Polyglucosan Bodies
Martin JE, Chowdhury ATMD, McElwaine S, Fikree A, Minassian B, Broad J, Knowles CH, Allen L, Bevan S, Burt E, Hymas AJ, Rahman MM, Rowburrey PJ, Sanger G, Thomas AA, Yiannakou Y, Cooper SC, Evagora CA, Levey PM, Cotter FE, et al.
JOURNAL OF PATHOLOGY. vol. 226, S24-S24.  
01-01-2012

Cysteine Scanning Mutagenesis and Disulfide Mapping Analysis of Arrangement of GspC and GspD Protomers within the Type 2 Secretion System
Wang X, Pineau C, Gu S, Guschinskaya N, Pickersgill RW and Shevchik VE
Journal of Biological Chemistry vol. 287 (23), 19082-19093.  
01-01-2012

An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis
Deery E, Schroeder S, Lawrence AD, Taylor SL, Seyedarabi A, Waterman J, Wilson KS, Brown D, Geeves MA, Howard MJ, Pickersgill RW and Warren MJ
Nature Chemical Biology vol. 8 (11), 933-940.  
01-01-2012

Joint neutron/X-ray crystallographic study on the mechanism of pectate lyase
Ali S, Texeira S and Pickersgill RW
Acta Crystallographica Section A: Foundations and advances. vol. 67 (a1), c734-c734.  
22-08-2011

A Novel Phenotype of Glycogen Storage Disease Presenting as Gastrointestinal Neuromuscular Disease
Martin JE, Chowdhury AH, McElwaine S, Fikree A, Broad J, Knowles CH, Allen L, Bevan S, Burt E, Hymas AJ, Rowburrey PJ, Sanger GJ, Rahman MM, Thomas AA, Yiannakou Y, Cooper SC, Evagora CA, Levey PM, Cotter FE, Aziz Q, et al.
Gastroenterology, Elsevier vol. 140 (5), s-705.  
01-05-2011

Structure of PduT, a trimeric bacterial microcompartment protein with a 4Fe-4S cluster-binding site.
Pang A, Warren MJ and Pickersgill RW
Acta Crystallogr D Biol Crystallogr vol. 67 (Pt 2), 91-96.  
01-02-2011

Evolution in a family of chelatases facilitated by the introduction of active site asymmetry and protein oligomerization
Romao CV, Ladakis D, Lobo SAL, Carrondo MA, Brindley AA, Deery E, Matias PM, Pickersgill RW, Saraiva LM and Warren MJ
P Natl Acad Sci Usa vol. 108 (1), 97-102.  
04-01-2011

A Novel Phenotype of Glycogen Storage Disease Presenting as Gastrointestinal Neuromuscular Disease
Martin JE, Chowdhury AH, McElwaine S, Fikree A, Broad J, Knowles CH, Allen L, Bevan S, Burt E, Hymas AJ, Rowburrey PJ, Sanger GJ, Rahman MM, Thomas AA, Yiannakou Y, Cooper SC, Evagora CA, Levey PM, Cotter FE, Ariz Q, et al.
GASTROENTEROLOGY. vol. 140 (5), S705-S705.  
01-01-2011

Cloning, purification and preliminary crystallographic analysis of cobalamin methyltransferases from Rhodobacter capsulatus.
Seyedarabi A, Hutchison T, To TT, Deery E, Brindley A, Warren MJ and Pickersgill RW
Acta Crystallogr Sect F Struct Biol Cryst Commun vol. 66 (Pt 12), 1652-1656.  
01-12-2010

A disulfide driven domain swap switches off the activity of Shigella IpaH9.8 E3 ligase.
Seyedarabi A, Sullivan JA, Sasakawa C and Pickersgill RW
Febs Lett vol. 584 (19), 4163-4168.  
08-10-2010

Millimeter wave spectroscopy of glucose and a calcium-binding protein using a vector network analyser
Shala K, Yang B, TT T, Pickersgill RW, Krauss N and Donnan RS
35th IRMMW-THZ Internation Conference, 2010 Rome, Italy 5 Sep 2010 - 10 Sep 2010., 1-2.  
01-10-2010

A 20-residue peptide of the inner membrane protein OutC mediates interaction with two distinct sites of the outer membrane secretin OutD and is essential for the functional type II secretion system in Erwinia chrysanthemi
Login FH, Fries M, Wang XH, Pickersgill RW and Shevchik VE
Molecular Microbiology, Blackwell Publishing Ltd vol. 76 (4), 944-955.  
21-04-2010

Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase.
Seyedarabi A, To TT, Ali S, Hussain S, Fries M, Madsen R, Clausen MH, Teixteira S, Brocklehurst K and Pickersgill RW
Biochemistry vol. 49 (3), 539-546.  
26-01-2010

Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization in Clostridium kluyveri
Heldt D, Frank S, Seyedarabi A, Ladikis D, Parsons JB, Warren MJ and Pickersgill RW
Biochem J vol. 423, 199-207.  
15-10-2009

Substrate Recognition
Brocklehurst K, Gul S and Pickersgill RW
In Amino Acids, Peptides and Proteins in Organic Chemistry, Wiley 473-504.  
23-09-2009

Enzyme sequence and its relationship to hyperbaric stability of artificial and natural fish lactate dehydrogenases.
Brindley AA, Pickersgill RW, Partridge JC, Dunstan DJ, Hunt DM and Warren MJ
Plos One vol. 3 (4) 
30-04-2008

Identification, characterization, and structure/function analysis of a corrin reductase involved in adenosylcobalamin biosynthesis
Lawrence AD, Deery E, McLean KJ, Munro AW, Pickersgill RW, Rigby SEJ and Warren MJ
J Biol Chem vol. 283 (16), 10813-10821.  
18-04-2008

Molecular basis of the activity of the phytopathogen pectin methylesterase.
Fries M, Ihrig J, Brocklehurst K, Shevchik VE and Pickersgill RW
Embo J vol. 26 (17), 3879-3887.  
05-09-2007

Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus.
Frank S, Deery E, Brindley AA, Leech HK, Lawrence A, Heathcote P, Schubert HL, Brocklehurst K, Rigby SEJ, Warren MJ and Pickersgill RW
J Biol Chem vol. 282 (33), 23957-23969.  
17-08-2007

Structure of internalin C from Listeria monocytogenes.
Ooi A, Hussain S, Seyedarabi A and Pickersgill RW
Acta Crystallogr D Biol Crystallogr vol. 62 (Pt 11), 1287-1293.  
01-11-2006

Structural and spectroscopic studies shed light on the mechanism of oxalate oxidase.
Opaleye O, Rose R-S, Whittaker MM, Woo E-J, Whittaker JW and Pickersgill RW
J Biol Chem vol. 281 (10), 6428-6433.  
10-03-2006

Characterization of retinaldehyde dehydrogenase 3.
Graham CE, Brocklehurst K, Pickersgill RW and Warren MJ
Biochem J vol. 394 (Pt 1), 67-75.  
15-02-2006

Anaerobic synthesis of vitamin B12: characterization of the early steps in the pathway.
Frank S, Brindley AA, Deery E, Heathcote P, Lawrence AD, Leech HK, Pickersgill RW and Warren MJ
Biochem Soc Trans vol. 33 (Pt 4), 811-814.  
01-08-2005

Shigella effector IpaH9.8 binds to a splicing factor U2AF(35) to modulate host immune responses
Okuda J, Toyotome T, Kataoka N, Ohno M, Abe H, Shimura Y, Seyedarabi A, Pickersgill R and Sasakawa C
Biochem Bioph Res Co vol. 333 (2), 531-539.  
29-07-2005

The crystal structure of pectate lyase Pel9A from Erwinia chrysanthemi
Jenkins J, Shevchik VE, Hugouvieux-Cotte-Pattat N and Pickersgill RW
J Biol Chem vol. 279 (10), 9139-9145.  
05-03-2004

A primordial structure underlying amyloid
Pickersgill RW
Structure vol. 11 (2), 137-138.  
01-02-2003

The structures and active sites of pectinases.
PICKERSGILL RW and Jenkins JA
International symposium on pectins and pectinases (2nd) Rotterdam, The Netherlands 1 Jan 1970., 267-278. Editors: Voragen AGJ, Voragen F, Schols H and Visser R. 
01-01-2003

Complex cell signaling molecules from ancient molecular glue
Pickersgill RW
Structure vol. 10 (10), 1287-1288.  
01-10-2002

Crystal structure of auxin-binding protein 1 in complex with auxin
Woo EJ, Marshall J, Bauly J, Chen JG, Venis M, Napier RM and Pickersgill RW
Embo J vol. 21 (12), 2877-2885.  
17-06-2002

A putative three-dimensional targeting motif of polygalacturonase (PehA), a protein secreted through the type II (GSP) pathway in Erwinia carotovora.
Palomäki T, Pickersgill R, Riekki R, Romantschuk M and Saarilahti HT
Mol Microbiol vol. 43 (3), 585-596.  
01-02-2002

Substrate specificity and subsite mobility in T. aurantiacus xylanase 10A.
Lo Leggio L, Kalogiannis S, Eckert K, Teixeira SC, Bhat MK, Andrei C, Pickersgill RW and Larsen S
Febs Lett vol. 509 (2), 303-308.  
07-12-2001

The architecture of parallel beta-helices and related folds
Jenkins J and Pickersgill R
Prog Biophys Mol Bio vol. 77 (2), 111-175.  
01-10-2001

Crystal structure of mannanase 26A from Pseudomonas cellulosa and analysis of residues involved in substrate binding.
Hogg D, Woo EJ, Bolam DN, McKie VA, Gilbert HJ and Pickersgill RW
J Biol Chem vol. 276 (33), 31186-31192.  
17-08-2001

Anisotropic refinement of the structure of Thermoascus aurantiacus xylanase I
Teixeira S, Lo Leggio L, Pickersgill R and Cardin C
Acta Crystallogr D vol. 57, 385-392.  
01-03-2001

Three-dimensional structure of Erwinia chrysanthemi pectin methylesterase reveals a novel esterase active site.
Jenkins J, Mayans O, Smith D, Worboys K and Pickersgill RW
J Mol Biol vol. 305 (4), 951-960.  
26-01-2001

Crystallization and preliminary X‐ray analysis of the auxin receptor ABP1
Woo EJ, Bauly J, Chen JG, Marshall J, Macdonald H, Lazarus C, Goodenough P, Venis M, Napier R and Pickersgill R
Acta Crystallographica Section D, Structural Biology, International Union of Crystallography (Iucr) vol. 56 (11), 1476-1478.  
01-11-2000

Germin is a manganese containing homohexamer with oxalate oxidase and superoxide dismutase activities
Woo E-J, Dunwell JM, Goodenough PW, Marvier AC and Pickersgill RW
Nature Structural & Molecular Biology, Springer Nature vol. 7 (11), 1036-1040.  
01-11-2000

X‐ray crystallographic study of xylopentaose binding to Pseudomonas fluorescens xylanase A
Leggio LL, Jenkins J, Harris GW and Pickersgill RW
Proteins Structure Function and Bioinformatics, Wiley vol. 41 (3), 362-373.  
01-01-2000

Xylanase–oligosaccharide interactions studied by a competitive enzyme assay
Leggio LL and Pickersgill RW
Enzyme and Microbial Technology, Elsevier vol. 25 (8-9), 701-709.  
01-11-1999

High resolution structure and sequence of T. aurantiacus Xylanase I: Implications for the evolution of thermostability in family 10 xylanases and enzymes with βα‐barrel architecture
Leggio LL, Kalogiannis S, Bhat MK and Pickersgill RW
Proteins Structure Function and Bioinformatics, Wiley vol. 36 (3), 295-306.  
15-08-1999

Ferulic acid esterase‐III from Aspergillus niger does not exhibit lipase activity
Aliwan FO, Kroon PA, Faulds CB, Pickersgill R and Williamson G
Journal of The Science of Food and Agriculture, Wiley vol. 79 (3), 457-459.  
01-03-1999

Crystallization and preliminary X‐ray analysis of arabinanase A from Pseudomonas fluorescens subspecies cellulosa
Scott M, Pickersgill RW, Hazlewood GP, Gilbert HJ and Harris GW
Acta Crystallographica Section D, Structural Biology, International Union of Crystallography (Iucr) vol. 55 (2), 544-546.  
01-02-1999

Crystallization and preliminary crystallographic analysis of the endo‐polygalacturonase from Erwinia carotovora ssp. carotovora
Pickersgill R, Scott M, Smith D, Worboys K and Jenkins J
Acta Crystallographica Section D, Structural Biology, International Union of Crystallography (Iucr) vol. 55 (1), 320-322.  
01-01-1999

Barley oxalate oxidase is a hexameric protein related to seed storage proteins: evidence from X‐ray crystallography
Woo E-J, Dunwell JM, Goodenough PW and Pickersgill RW
Febs Letters, Wiley vol. 437 (1-2), 87-90.  
16-10-1998

Crystal Structure of Polygalacturonase from Erwinia carotovora ssp. carotovora *
Pickersgill R, Smith D, Worboys K and Jenkins J
Journal of Biological Chemistry, Elsevier vol. 273 (38), 24660-24664.  
01-09-1998

Superfamilies: the 4/7 superfamily of βα-barrel glycosidases and the right-handed parallel β-helix superfamily
Pickersgill R, Harris G, Leggio LL, Mayans O and Jenkins J
Biochemical Society Transactions. vol. 26 (2), 190-197.  
01-05-1998

Chemical and thermal stability of ferulic acid (feruloyl) esterases from Aspergillus
Faulds CB, Aliwan FO, de Vries RP, Pickersgill RW, Visser J and Williamson G
Progress in Biotechnology, Elsevier vol. 15, 41-46.  
01-01-1998

Crystallization and preliminary X‐ray diffraction studies of a family 26 endo‐β‐1,4 mannanase (ManA) from Pseudomonas fluorescens subspecies cellulosa
Scott M, Pickersgill RW, Hazlewood GP, Bolam D, Gilbert HJ and Harris GW
Acta Crystallographica Section D, Structural Biology, International Union of Crystallography (Iucr) vol. 54 (1), 129-131.  
01-01-1998

Structure and Evolution of Parallel β-Helix Proteins
Jenkins J, Mayans O and Pickersgill R
Journal of Structural Biology, Elsevier vol. 122 (1-2), 236-246.  
01-01-1998

Structural basis of the properties of an industrially relevant thermophilic xylanase
Harris GW, Pickersgill RW, Connerton I, Debeire P, Touzel J, Breton C and Pérez S
Proteins Structure Function and Bioinformatics, Wiley vol. 29 (1), 77-86.  
01-09-1997

Crystallization and preliminary X‐ray analysis of the major endoglucanase from Thermoascus aurantiacus
Lo Leggio L, Parry NJ, Van Beeumen J, Claeyssens M, Bhat MK and Pickersgill RW
Acta Crystallographica Section D, Structural Biology, International Union of Crystallography (Iucr) vol. 53 (5), 599-604.  
01-09-1997

Calcium Protects a Mesophilic Xylanase from Proteinase Inactivation and Thermal Unfolding*
Spurway TD, Morland C, Cooper A, Sumner I, Hazlewood GP, O'Donnell AG, Pickersgill RW and Gilbert HJ
Journal of Biological Chemistry, Elsevier vol. 272 (28), 17523-17530.  
01-07-1997

Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases
Mayans O, Scott M, Connerton I, Gravesen T, Benen J, Visser J, Pickersgill R and Jenkins J
Structure, Elsevier vol. 5 (5), 677-689.  
01-05-1997

Key Residues in Subsite F Play a Critical Role in the Activity of Pseudomonas fluorescens Subspecies cellulosa Xylanase A Against Xylooligosaccharides but Not Against Highly Polymeric Substrates such as Xylan*
Charnock SJ, Lakey JH, Virden R, Hughes N, Sinnott ML, Hazlewood GP, Pickersgill R and Gilbert HJ
Journal of Biological Chemistry, Elsevier vol. 272 (5), 2942-2951.  
01-01-1997

The prosequence of procaricain forms an α-helical domain that prevents access to the substrate-binding cleft
Groves MR, Taylor MA, Scott M, Cummings NJ, Pickersgill RW and Jenkins JA
Structure, Elsevier vol. 4 (10), 1193-1203.  
01-10-1996

Crystal structure of a caricain D158E mutant in complex with E‐64
Katerelos NA, Taylor MAJ, Scott M, Goodenough PW and Pickersgill RW
Febs Letters, Wiley vol. 392 (1), 35-39.  
19-08-1996

Crystallization and preliminary X‐ray analysis of pectin lyase A from Aspergillus niger
Jenkins J, Scott M, Mayans O, Pickersgill R, Harris G, Connerton I and Gravesen T
Acta Crystallographica Section D, Structural Biology, International Union of Crystallography (Iucr) vol. 52 (2), 402-404.  
01-03-1996

Refined Crystal Structure of the Catalytic Domain of Xylanase A from Pseudomonas fluorescens at 1.8 Å Resolution
Harris GW, Jenkins JA, Connerton I and Pickersgill RW
Acta Crystallographica Section D, Structural Biology, International Union of Crystallography (Iucr) vol. 52 (2), 393-401.  
01-03-1996

β‐Glucosidase, β‐galactosidase, family A cellulases, family F xylanases and two barley glycanases form a superfamily of enzymes wit 8‐fold β/α architecture and with two conserved glutamates near the carboxy‐terminal ends of β‐strands four and seven
Jenkins J, Leggio LL, Harris G and Pickersgill R
Febs Letters, Wiley vol. 362 (3), 281-285.  
10-04-1995

The potent mitogen Pasteurella multocida toxin is highly resistant to proteolysis but becomes susceptible at lysosomal pH
Smyth MG, Pickersgill RW and Lax AJ
Febs Letters, Wiley vol. 360 (1), 62-66.  
20-02-1995

Structure of the catalytic core of the family F xylanase from Pseudomonas fluorescens and identification of the xylopentaose-binding sites
Harris GW, Jenkins JA, Connerton I, Cummings N, Leggio LL, Scott M, Hazlewood GP, Laurie JI, Gilbert HJ and Pickersgill RW
Structure, Elsevier vol. 2 (11), 1107-1116.  
01-11-1994

The structure of Bacillus subtilis pectate lyase in complex with calcium
Pickersgill R, Jenkins J, Harris G, Nasser W and Robert-Baudouy J
Nature Structural & Molecular Biology, Springer Nature vol. 1 (10), 717-723.  
01-10-1994

Making a small enzyme smaller; removing the conserved loop structure of hen lysozyme
Pickersgill R, Varvill K, Jones S, Perry B, Fischer B, Henderson I, Garrard S, Sumner I and Goodenough P
Febs Letters, Wiley vol. 347 (2-3), 199-202.  
27-06-1994

An unequivocal example of cysteine proteinase activity affected by multiple electrostatic interactions
Taylor MAJ, Baker KC, Connerton IF, Cummings NJ, Harris GW, Henderson IMJ, Jones ST, Pickersgill RW, Sumner IG, Warwicker J and Goodenough PW
Protein Engineering Design and Selection, Oxford University Press (Oup) vol. 7 (10), 1267-1276.  
01-01-1994

Crystal structure determination and refinement at 2.3-A resolution of the lentil lectin.
Loris R, Steyaert J, Maes D, Lisgarten J, Pickersgill R and Wyns L
Biochemistry, American Chemical Society (Acs) vol. 32 (51) 
01-12-1993

Modification of the head-group selectivity of porcine pancreatic phospholipase A2 by protein engineering.
Bhat MK, Pickersgill RW, Perry BN, Brown RA, Jones ST, Mueller-Harvey I, Sumner IG and Goodenough PW
Biochemistry, American Chemical Society (Acs) vol. 32 (45), 12203-12208.  
01-11-1993

Kinetic analysis of papaya proteinase Ω
Sumner IG, Vaughan A, Eisenthal R, Pickersgill RW, Owen AJ and Goodenough PW
Biochimica Et Biophysica Acta, Elsevier vol. 1164 (3), 243-251.  
01-08-1993

Factors effecting the thermostability of cysteine proteinases from Carica papaya
SUMNER IG, HARRIS GW, TAYLOR MAJ, PICKERSGILL RW, OWEN AJ and GOODENOUGH PW
The Febs Journal, Wiley vol. 214 (1), 129-134.  
01-05-1993

Nucleotide sequence and expression in Eschericia coli of cDNAs encoding papaya proteinase omega from Carica papaya
Reveil DF, Cummings NJ, Baker KC, Collins ME, Taylor MAJ, Sumner IG, Pickersgill RW, Connerton IF and Goodenough PW
Gene, Elsevier vol. 127 (2), 221-225.  
01-05-1993

Crystals of β-Xylanase from Aspergillus oryzae
Golubev AM, Kilimnik AY, Neustroev KN and Pickersgill RW
Journal of Molecular Biology, Elsevier vol. 230 (2), 661-663.  
01-03-1993

Crystallization and Preliminary X-ray Analysis of a Thermophilic Bacillus Xylanase
Pickersgill RW, Debeire P, Debeire-Gosselin M and Jenkins JA
Journal of Molecular Biology, Elsevier vol. 230 (2), 664-666.  
01-03-1993

Molecular dynamics simulation of a phospholipase A2-substrate complex
Jones ST, Ahlström P, Berendsen HJC and Pickersgill RW
Biochimica Et Biophysica Acta, Elsevier vol. 1162 (1-2), 135-142.  
01-03-1993

Crystallization and Preliminary X-ray Analysis of the Catalytic Domain of Xylanase A from Pseudomonas fluorescens subspecies cellulosa
Pickersgill RW, Jenkins JA, Scott M, Connerton I, Hazlewood GP and Gilbert HJ
Journal of Molecular Biology, Elsevier vol. 229 (1), 246-248.  
01-01-1993

Design and engineering of hydrolytic enzymes for enhanced performance in the agricultural and food industries
Pickersgill RW
Journal of Chemical Technology & Biotechnology, Wiley vol. 57 (3), 290-291.  
01-01-1993

Corrections: Crystal Structure Determination and Refinement at 2.3-Å Resolution of the Lentil Lectin (Biochemistry (1993) 32(34) (8772–8781) (10.1021/bi00085a007))
Loris R, Steyaert J, Maes D, Lisgarten J, Pickersgill R and Wyns L
Biochemistry vol. 32 (51) 
01-01-1993

Crystallization and preliminary X-ray studies of the pectate lyase from Bacillus subtilis
Jenkins J, Nasser W, Scott M, Pickersgill R, Vignon J-C and Robert-Baudouy J
Journal of Molecular Biology, Elsevier vol. 228 (4), 1255-1258.  
01-12-1992

Structure of monoclinic papain at 1.60 Å resolution
Pickersgill RW, Harris GW and Garman E
Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, International Union of Crystallography (Iucr) vol. 48 (1), 59-67.  
01-02-1992

The segmented anisotropic refinement of monoclinic papain by the application of the rigid‐body TLS model and comparison to bovine ribonuclease A
Harris GW, Pickersgill RW, Howlin B and Moss DS
Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, International Union of Crystallography (Iucr) vol. 48 (1), 67-75.  
01-02-1992

Two crystal forms of the lentil lectin diffract to high resolution
Loris R, Lisgarten J, Maes D, Pickersgill R, Körber F, Reynolds C and Wyns L
Journal of Molecular Biology, Elsevier vol. 223 (2), 579-581.  
01-01-1992

Determination of the structure of papaya protease omega
Pickersgill RW, Rizkallah P, Harris GW and Goodenough PW
Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, International Union of Crystallography (Iucr) vol. 47 (5), 766-771.  
01-10-1991

Modification of the stability of phospholipase A2 by charge engineering
Pickersgill RW, Sumner IG, Collins ME, Warwicker J, Perry B, Bhat KM and Goodenough PW
Febs Letters, Wiley vol. 281 (1-2), 219-222.  
09-04-1991

A novel method for the purification of porcine phospholipase A2 expressed in E.coli
Bhat KM, Sumner IG, Perry BN, Collins ME, Pickersgill RW and Goodenough PW
Biochemical and Biophysical Research Communications, Elsevier vol. 176 (1), 371-377.  
01-04-1991

Changes in activity of porcine phospholipase A2 brought about by charge engineering of a major structural element to alter stability
Goodenough PW, Bhat KM, Collins ME, Perry BN, Pickersgill RW, Sumner IG, Warwicker J, de Haas GH and Verheij HM
Protein Engineering Design and Selection, Oxford University Press (Oup) vol. 4 (8), 929-934.  
01-01-1991

Enzyme engineering
Pickersgill RW and Goodenough PW
Trends in Food Science & Technology, Elsevier vol. 2, 122-126.  
01-01-1991

Preliminary crystallographic data for protease Ω
PICKERSGILL RW, SUMNER IG and GOODENOUGH PW
The Febs Journal, Wiley vol. 190 (2), 443-444.  
01-06-1990

Structural and electrostatic differences between actinidin and papain account for differences in activity
Pickersgill RW, Sumner IG, Collins ME and Goodenough PW
Biochemical Journal, Portland Press vol. 257 (1), 310-312.  
01-01-1989

The electrostatic fields in the active-site clefts of actinidin and papain
Pickersgill RW, Goodenough PW, Sumner IG and Collins ME
Biochemical Journal, Portland Press vol. 254 (1), 235-238.  
15-08-1988

A rapid method of calculating charge–charge interaction energies in proteins
Pickersgill RW
Protein Engineering Design and Selection, Oxford University Press (Oup) vol. 2 (3), 247-248.  
01-01-1988

One‐dimensional disorder in spinach ribulose bisphosphate carboxylase crystals
Pickersgill RW
Acta Crystallographica Section a: Foundations and Advances, International Union of Crystallography (Iucr) vol. 43 (4), 502-506.  
01-07-1987

Structure-function relationships of NAD+- and NADP+-dependent dehydrogenases with particular reference to the three-dimensional structure of 6-phosphogluconate dehydrogenase
ADAMS MJ, GOVER S, PICKERSGILL RW and HELLIWELL JR
Biochemical Society Transactions, Portland Press vol. 11 (4), 429-435.  
01-08-1983

The three dimensional structure of sheep liver 6‐phosphogluconate dehydrogenase at 2.6 A resolution.
Adams MJ, Archibald IG, Bugg CE, Carne A, Gover S, Helliwell JR, Pickersgill RW and White SW
The Embo Journal, Springer Nature vol. 2 (6), 1009-1014.  
01-06-1983