Dr Benjamin Stieglitz

N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling
Kliza KW, Song W, Pinzuti I, Schaubeck S, Kunzelmann S, Kuntin D, Fornili A, Pandini A, Hofmann K, Garnett JA, Stieglitz B and Husnjak K
Cell Death Discovery, Springer Nature vol. 10 (1) 
20-04-2024

HHARI in motion reveals an unexpected substrate recognition site for RBR ligases
Stieglitz B
Structure, Elsevier vol. 30 (9), 1221-1223.  
01-09-2022

Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development
Green JL, Wu Y and Stieglitz B
Plos Pathogens, Public Library of Science (Plos) vol. 16 (6), e1008640-e1008640.  
22-06-2020

Auxiliary-assisted chemical ubiquitylation of NEMO and linear extension by HOIP
Burlina F, Abdel-Aal A-BM, Raz R, Pinzuti I, Papageorgiou G, Li J, Antrobus R, Martin SR, Kunzelmann S, Stieglitz B and Offer J
Communications Chemistry, Springer Science and Business Media Llc vol. 2 (1) 
19-09-2019

Internally Tagged Ubiquitin: a Tool to Identify Linear Polyubiquitin-modified Proteins by Mass Spectrometry
Kliza K, Taumer C, Pinzuti I, Franz-Wachtel M, Kunzelmann S, STIEGLITZ B, Macek B and Husnjak K
Nature Methods, Nature Publishing Group 
20-03-2017

Determination of the pKa of the N-terminal amino group of ubiquitin by NMR
Oregioni A, STIEGLITZ B, Kelly G, Rittinger K and Frenkiel T
Scientific Reports, Nature Publishing Group, 1-8.  
02-03-2017

Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms
Dove KK, Stieglitz B, Duncan ED, Rittinger K and Klevit RE
Embo Reports, Embo Press 
16-06-2016

Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
Stieglitz B, Rana RR, Koliopoulos MG, Morris-Davies AC, Schaeffer V, Christodoulou E, Howell S, Brown NR, Dikic I and Rittinger K
Nature, Springer Nature vol. 503 (7476), 422-426.  
20-10-2013

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
Stieglitz B, Morris‐Davies AC, Koliopoulos MG, Christodoulou E and Rittinger K
Embo Reports, Springer Nature vol. 13 (9), 840-846.  
13-07-2012

Crystallization of SHARPIN using an automated two‐dimensional grid screen for optimization
Stieglitz B, Rittinger K and Haire LF
Acta Crystallographica Section F: Structural Biology Communications, International Union of Crystallography (Iucr) vol. 68 (7), 816-819.  
28-06-2012

Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold*
Stieglitz B, Haire LF, Dikic I and Rittinger K
Journal of Biological Chemistry, Elsevier vol. 287 (25), 20823-20829.  
01-05-2012

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
Wilhelm C, Hirota K, Stieglitz B, Van Snick J, Tolaini M, Lahl K, Sparwasser T, Helmby H and Stockinger B
Nature Immunology, Springer Nature vol. 12 (11), 1071-1077.  
09-10-2011

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
Ikeda F, Deribe YL, Skånland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJL, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B and Dikic I
Nature, Springer Nature vol. 471 (7340), 637-641.  
01-03-2011

Novel sources of IL-9 in lung inflammation
Wilhelm C, Hirota K, Stieglitz B, Van Snick J, Tolaini M, Lahl K, Sparwasser T, Helmby H and Stockinger B
IMMUNOLOGY. vol. 135, 128-128.  
01-01-2011

Growth and Tumor Suppressor NORE1A Is a Regulatory Node between Ras Signaling and Microtubule Nucleation*
Bee C, Moshnikova A, Mellor CD, Molloy JE, Koryakina Y, Stieglitz B, Khokhlatchev A and Herrmann C
Journal of Biological Chemistry, Elsevier vol. 285 (21), 16258-16266.  
25-03-2010

Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II
Stieglitz B, Bee C, Schwarz D, Yildiz Ö, Moshnikova A, Khokhlatchev A and Herrmann C
The Embo Journal, Springer Nature vol. 27 (14), 1995-2005.  
03-07-2008

Crystal structure of the Clostridium limosum C3 exoenzyme
Vogelsgesang M, Stieglitz B, Herrmann C, Pautsch A and Aktories K
Febs Letters, Wiley vol. 582 (7), 1032-1036.  
04-03-2008

Ras/Nore1 interaction: mechanism of apoptotic signaling
Herrmann C and Stieglitz B
Acta Crystallographica Section A: Foundations and advances. vol. 63 (a1), s16-s16.  
22-08-2007