Prof Richard Nichols
Professor of Evolutionary Genetics
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
Population Genetics, Evolutionary Genomics, Bayesian Analysis, Conservation, Range Expansion, Invasive Species
Interests
My work combines the collection of genetic data with the development of new analytical methods. I interpret genetic patterns to ask how populations have spread or contracted, merged or been fragmented and how they have been shaped by natural selection.I apply this approach to a wide diversity of organisms:
Trees: I work with colleagues at Kew to counteract threats to British trees, encompassing projects to identify the genetic basis of resistance to invasive diseases of Ash trees (with Richard Buggs) and exploiting phylogenetic information to anticipate threats from invasive beetles (with Laura Kelly).
Viruses: with Trent Garner (Institute of Zoology) I study the spread of wildlife viruses affecting fish, reptiles, and amphibians. I ask why they have recently appeared in new locations & species.
Human cancer cells: I work with Trevor Graham (Barts Cancer Institute) using experiments on cancer cell lines to ask if we can identify strategies to retard resistance to chemotherapy, by exploiting evolutionary insights.
Model organisms: conducting experimental evolution, for example on Drosophila fruit flies (with Bill Sherwin in UNSW), I ask if there are flaws or omissions in our current evolutionary models.
Crops: I am a member of a project with (The Natural Resources Institute and Kew) to identify crop varieties that will be resilient to climate change in Ethiopia.
Publications
Publications of specific relevance to the Centre for Evolutionary and Functional Genomics2024
Nitrogen and phosphorus interactions at a 21 nitrogen:1 phosphorus Redfield‐like ratio impact growth and seed yield in wheat (Triticum aestivum L.)da Silva SSM, Faizullah L, Guignard MS, Orcen N, Ruban AV, Rudall PJ, Trimmer M, Nichols RA, Leitch IJ and Leitch AR
Food and Energy Security, Wiley vol. 13 (4)
30-07-2024
2023
Maintenance and expansion of genetic and trait variation following domestication in a clonal cropWhite OW, Biswas MK, Abebe WM, Dussert Y, Kebede F, Nichols RA, Buggs RJA, Demissew S, Woldeyes F, Papadopulos AST, Schwarzacher T, Heslop‐Harrison PJS, Wilkin P and Borrell JS
Molecular Ecology, Wiley vol. 32 (15), 4165-4180.
02-06-2023
Assembly‐free quantification of vagrant DNA insertsBecher H and Nichols RA
Molecular Ecology Resources, Wiley vol. 23 (5), 1002-1013.
15-02-2023
2022
Non-Lethal Detection of Frog Virus 3-Like (RUK13) and Common Midwife Toad Virus-Like (PDE18) Ranaviruses in Two UK-Native Amphibian SpeciesFord CE, Brookes LM, Skelly E, Sergeant C, Jordine T, Balloux F, Nichols RA and Garner TWJ
Viruses, Mdpi vol. 14 (12)
25-11-2022
Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cellLau Y, Oamen HP, Grogg M, Parfenova I, Saarikangas J, Hannay R, Nichols RA, Hilvert D, Barral Y and Caudron F
Current Biology, Elsevier vol. 32 (5), 963-974.e7.
31-01-2022
Cyto-nuclear incompatibilities across a bluebell hybrid zone in northern Spain do not prevent genome-wide introgression of neutral markersMarquardt J, Blanckaert A, Nichols RA, Ansell SW, Ruhsam M, Hollingsworth PM, Metzler D, Schneider H and Leitch AR
Evolutionary Journal of The Linnean Society, Oxford University Press (Oup) vol. 1 (1), kzac003-kzac003.
01-01-2022
2021
Evidence for the Widespread Occurrence of Bacteria Implicated in Acute Oak Decline from Incidental Genetic SamplingGathercole LAP, Nocchi G, Brown N, Coker TLR, Plumb WJ, Stocks JJ, Nichols RA, Denman S and Buggs RJA
Forests vol. 12 (12), 1683-1683.
01-12-2021
Spatially clustered count data provide more efficient search strategies in invasion biology and disease control.Stevens MCA, Faulkner SC, Wilke ABB, Beier JC, Vasquez C, Petrie W, Fry H, Nichols RA, Verity R and Le Comber SC
Ecol Appl, Ecological Society of America, e2329-e2329.
22-03-2021
2020
Correction: Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants.Martinez-Ruiz C, Pracana R, Stolle E, Paris CI, Nichols RA and Wurm Y
Elife, Elife Sciences Publications Ltd vol. 9
09-11-2020
Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire antsMartinez-Ruiz C, Pracana R, Stolle E, Paris CI, Nichols RA and Wurm Y
Elife, Elife vol. 9
10-08-2020
2019
Genomic basis of European ash tree resistance to ash dieback fungusStocks J, Metheringham C, Plumb W, Lee S, Kelly L, Nichols R and Buggs R
Nature Ecology and Evolution, Nature Research
18-11-2019
Genomic assessment of local adaptation in dwarf birch to inform assisted gene flowBORRELL J, ZOHREN J, Nichols R and Buggs R
Evolutionary Applications: Evolutionary Approaches to Environmental, Biomedical and Socio-Economic Issues, Wiley
20-10-2019
Modelling Ranavirus Transmission in Populations of Common Frogs (Rana temporaria) in the United KingdomDuffus ALJ, Garner TWJ, Nichols RA, Standridge JP and Earl JE
Viruses, Mdpi vol. 11 (6)
15-06-2019
Effects of historic and projected climate change on the range and impacts of an emerging wildlife diseasePrice SJ, Leung WTM, Owen CJ, Puschendorf R, Sergeant C, Cunningham AA, Balloux F, Garner TWJ and Nichols RA
Global Change Biology, Wiley vol. 25 (8), 2648-2660.
09-05-2019
Interactions between plant genome size, nutrients and herbivory by rabbits, molluscs and insects on a temperate grasslandGuignard MS, Crawley MJ, Kovalenko D, Nichols RA, Trimmer M, Leitch AR and Leitch IJ
Proceedings of The Royal Society B, The Royal Society vol. 286 (1899)
20-03-2019
Genome-wide haplotype analysis improves trait predictions in Brassica napus hybridsJan HU, Guan M, Yao M, Liu W, Wei D, Abbadi A, Zheng M, He X, Chen H, Guan C, Nichols RA, Snowdon RJ, Hua W and Qian L
Plant Science vol. 283, 157-164.
13-03-2019
2018
Genetic diversity maintained among fragmented populations of a tree undergoing range contraction.Borrell JS, Wang N, Nichols RA and Buggs RJA
Heredity (Edinb) vol. 121 (4), 304-318.
01-10-2018
2017
The fire ant social chromosome supergene variant Sb shows low diversity but high divergence from SBPracana R, Priyam A, Levantis I, Nichols RA and Wurm Y
Molecular Ecology, Wiley vol. 26 (11), 2864-2879.
01-04-2017
Genetic linkage to explain genetic variationMijangos JL, Holleley CE, Nichols RA, Towers IN, Jovanoski Z, Sidhu HS, Watt S, Adamack AT and Sherwin WB
Proceedings - 22nd International Congress on Modelling and Simulation, MODSIM 2017., 127-133.
01-01-2017
2016
Reconstructing the emergence of a lethal infectious disease of wildlife supports a key role for spread through translocations by humans.Price SJ, Garner TW, Cunningham AA, Langton TE and Nichols RA
Proc Biol Sci vol. 283 (1839)
28-09-2016
Estimating the Number of Subpopulations (K) in Structured PopulationsVerity R and Nichols RA
Genetics: a Periodical Record of Investigations Bearing On Heredity and Variation, Genetics Society of America vol. 203 (4), 1827-1839.
01-08-2016
Documentation for MAVERICK software: Version 1.0Verity R and Nichols RA
Genetics vol. 203 (4)
01-08-2016
File s1: Derivation of evidence estimators and model comparison statisticsVerity R and Nichols RA
Genetics vol. 203 (4)
01-08-2016
Unidirectional diploid-tetraploid introgression among British birch trees with shifting ranges shown by RAD markersZohren J, Wang N, Kardailsky I, Borrell JS, Joecker A, Nichols RA and Buggs RJA
Molecular Ecology, Wiley: 12 Months
11-05-2016
Genome size and ploidy influence angiosperm species’ biomass under nitrogen and phosphorus limitationGuignard MS, Nichols RA, Knell RJ, Macdonald A, Romila C-A, Trimmer M, Leitch IJ and LEITCH AR
New Phytologist, John Wiley & Sons, Inc
15-02-2016
Genomic Prediction of Testcross Performance in Canola (Brassica napus)Jan HU, Abbadi A, Lücke S, Nichols RA and Snowdon RJ
Plos One, Public Library of Science (Plos) vol. 11 (1)
29-01-2016
2015
Analysis of the giant genomes of Fritillaria (Liliaceae) indicates that a lack of DNA removal characterizes extreme expansions in genome sizeKelly LJ, Renny‐Byfield S, Pellicer J, Macas J, Novák P, Neumann P, Lysak MA, Day PD, Berger M, Fay MF, Nichols RA, Leitch AR and Leitch IJ
New Phytologist, Wiley vol. 208 (2), 596-607.
08-06-2015
Rates of Vaccine Evolution Show Strong Effects of Latency: Implications for Varicella Zoster Virus EpidemiologyWeinert LA, Depledge DP, Kundu S, Gershon AA, Nichols RA, Balloux F, Welch JJ and Breuer J
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 32 (4), 1020-1028.
06-01-2015
2014
Detection of a frog virus 3-like ranavirus in native and introduced amphibians in the United Kingdom in 2007 and 2008Duffus ALJ, Nichols RA and Garner TWJ
Herpetological Review vol. 45 (4), 608-610.
01-12-2014
Experimental evidence in support of single host maintenance of a multihost pathogenDuffus ALJ, Nichols RA and Garner TWJ
Ecosphere, Wiley vol. 5 (11), 1-11.
01-11-2014
Collapse of Amphibian Communities Due to an Introduced RanavirusPrice SJ, Garner TWJ, Nichols RA, Balloux F, Ayres C, de Alba AM-C and Bosch J
Current Biology, Elsevier vol. 24 (21), 2586-2591.
16-10-2014
What is genetic differentiation, and how should we measure it--GST, D, neither or both?Verity R and Nichols RA
Mol Ecol vol. 23 (17), 4216-4225.
01-09-2014
Molecular footprints of the Holocene retreat of dwarf birch in Britain.Wang N, Borrell JS, Bodles WJA, Kuttapitiya A, Nichols RA and Buggs RJA
Mol Ecol vol. 23 (11), 2771-2782.
01-06-2014
Inside the Melanoplinae: new molecular evidence for the evolutionary history of the Eurasian Podismini (Orthoptera: Acrididae).Chintauan-Marquier IC, Amédégnato C, Nichols RA, Pompanon F, Grandcolas P and Desutter-Grandcolas L
Mol Phylogenet Evol vol. 71, 224-233.
01-02-2014
Spatial targeting of infectious disease control: Identifying multiple, unknown sourcesVerity R, Stevenson MD, Rossmo DK, Nichols RA and Le Comber SC
Methods in Ecology and Evolution vol. 5 (7), 647-655.
01-01-2014
Testing single-sample estimators of effective population size in genetically structured populationsHolleley CE, Nichols RA, Whitehead MR, Adamack AT, Gunn MR and Sherwin WB
Conservation Genetics vol. 15 (1), 23-35.
01-01-2014
Purifying selection in deeply conserved human enhancers is more consistent than in coding sequences.De Silva DR, Nichols R and Elgar G
Plos One vol. 9 (7)
01-01-2014
Molecular footprints of the Holocene retreat of dwarf birch in BritainWang N, Borrell JS, Bodles WJA, Kuttapitiya A, Nichols RA and Buggs RJA
Molecular Ecology
01-01-2014
2013
Conservation Genetic Resources for Effective Species Survival (ConGRESS): Bridging the divide between conservation research and practiceHoban S, Arntzen JW, Bertorelle G, Bryja J, Fernandes M, Frith K, Gaggiotti O, Galbusera P, Godoy JA, Hauffe HC, Rus Hoelzel A, Nichols RA, Pérez-Espona S, Primmer C, Russo IRM, Segelbacher G, Siegismund HR, Sihvonen M, Sjögren-Gulve P, Vernesi C, et al.
Journal For Nature Conservation vol. 21 (6), 433-437.
01-12-2013
Investigations into the life history stages of the common frog (Rana temporaria) affected by an amphibian ranavirus in the United KingdomDuffus ALJ, Nichols RA and Garner TWJ
Herpetological Review vol. 44 (2), 260-263.
01-12-2013
Deep Sequencing of Viral Genomes Provides Insight into the Evolution and Pathogenesis of Varicella Zoster Virus and Its Vaccine in HumansDepledge DP, Kundu S, Jensen NJ, Gray ER, Jones M, Steinberg S, Gershon A, Kinchington PR, Schmid DS, Balloux F, Nichols RA and Breuer J
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 31 (2), 397-409.
25-10-2013
Diploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences.Renny-Byfield S, Kovarik A, Kelly LJ, Macas J, Novak P, Chase MW, Nichols RA, Pancholi MR, Grandbastien M-A and Leitch AR
Plant J vol. 74 (5), 829-839.
01-06-2013
Diploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequencesRenny-Byfield S, Kovarik A, Kelly LJ, MacAs J, Novak P, Chase MW, Nichols RA, Pancholi MR, Grandbastien MA and Leitch AR
Plant Journal vol. 74 (5), 829-839.
01-06-2013
Godfrey M Hewitt (1940-2013): highlights in Heredity from a career in evolutionary genetics.Nichols RA, Butlin RK and Bruford MW
Heredity (Edinb) vol. 110 (5), 405-406.
01-05-2013
Hybridization and speciationAbbott R, Albach D, Ansell S, Arntzen JW, Baird SJE, Bierne N, Boughman JW, Brelsford A, Buerkle CA, Buggs R, Butlin RK, Dieckmann U, Eroukhmanoff F, Grill A, Cahan SH, Hermansen JS, Hewitt G, Hudson AG, Jiggins C, Jones J, et al.
Journal of Evolutionary Biology vol. 26 (2), 229-246.
01-01-2013
Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploidsMatyasek R, Renny-Byfield S, Fulnecek J, Macas J, Grandbastien M-A, Nichols R, Leitch A and Kovarik A
Bmc Genomics, Biomed Central Ltd vol. 13 (722)
01-01-2013
Bringing genetic diversity to the forefront of conservation policy and managementHoban SM, Hauffe HC, Perez-Espona S, Arntzen JW, Bertorelle G, Bryja J, Frith K, Gaggiotti OE, Galbusera P, Godoy JA, Hoelzel AR, Nichols RA, Primmer CR, Russo I-R, Segelbacher G, Siegismund HR, Sihvonen M, Vernesi C, Vila C and Bruford MW
Conservation Genetics Resources vol. 5 (2), 593-598.
01-01-2013
Conservation Genetic Resources for Effective Species Survival (ConGRESS): Bridging the divide between conservation research and practiceHoban S, Arntzen JW, Bertorelle G, Bryja J, Fernandes M, Frith K, Gaggiotti O, Galbusera P, Godoy JA, Hauffe HC, Rus Hoelzel A, Nichols RA, Pérez-Espona S, Primmer C, Russo I-RM, Segelbacher G, Siegismund HR, Sihvonen M, Sjögren-Gulve P, Vernesi C, et al.
Journal For Nature Conservation
01-01-2013
Sample Planning Optimization Tool for conservation and population Genetics (SPOTG): a software for choosing the appropriate number of markers and samplesHoban S, Gaggiotti O, Bertorelle G, Arntzen P, Bryja J, Fernandes M, Frith K, Galbusera P, Godoy JA, Hauffe HC, Hoelzel R, Nichols R, Perez-Espona S, Primmer C, Russo I-RM, Segelbacher G, Siegismund HR, Sihvonen M, Sjoegren-Gulve P, Vernesi C, et al.
Methods in Ecology and Evolution vol. 4 (3), 299-303.
01-01-2013
2012
Independent, rapid and targeted loss of highly repetitive DNA in natural and synthetic allopolyploids of Nicotiana tabacum.Renny-Byfield S, Kovařík A, Chester M, Nichols RA, Macas J, Novák P and Leitch AR
Plos One vol. 7 (5)
01-01-2012
2011
Next generation sequencing reveals genome downsizing in allotetraploid Nicotiana tabacum, predominantly through the elimination of paternally derived repetitive DNAs.Renny-Byfield S, Chester M, Kovařík A, Le Comber SC, Grandbastien M-A, Deloger M, Nichols RA, Macas J, Novák P, Chase MW and Leitch AR
Mol Biol Evol vol. 28 (10), 2843-2854.
01-10-2011
Predictions of single-nucleotide polymorphism differentiation between two populations in terms of mutual information.Dewar RC, Sherwin WB, Thomas E, Holleley CE and Nichols RA
Mol Ecol vol. 20 (15), 3156-3166.
01-08-2011
Stops making sense: translational trade-offs and stop codon reassignment.Johnson LJ, Cotton JA, Lichtenstein CP, Elgar GS, Nichols RA, Polly PD and Le Comber SC
Bmc Evol Biol vol. 11
29-07-2011
Population diversity in batches of the varicella Oka vaccineKanda RK, Quinlivan ML, Gershon AA, Nichols RA and Breuer J
Vaccine vol. 29 (17), 3293-3298.
12-04-2011
Household size is critical to varicella-zoster virus transmission in the tropics despite lower viral infectivity.Nichols RA, Averbeck KT, Poulsen AG, al Bassam MM, Cabral F, Aaby P and Breuer J
Epidemics vol. 3 (1), 12-18.
01-03-2011
Induced dispersal in wildlife management: experimental evaluation of the risk of hybrid breakdown and the benefit of hybrid vigor in the F1 generationHolleley CE, Nichols RA, Whitehead MR, Gunn MR, Gupta J and Sherwin WB
Conserv Genet vol. 12 (1), 31-40.
01-02-2011
Phylogenetic relationships in Pterodroma petrels are obscured by recent secondary contact and hybridization.Brown RM, Jordan WC, Faulkes CG, Jones CG, Bugoni L, Tatayah V, Palma RL and Nichols RA
Plos One vol. 6 (5)
01-01-2011
2010
Range expansion and hybridization in Round Island petrels (Pterodroma spp.): evidence from microsatellite genotypes.Brown RM, Nichols RA, Faulkes CG, Jones CG, Bugoni L, Tatayah V, Gottelli D and Jordan WC
Mol Ecol vol. 19 (15), 3157-3170.
01-08-2010
2009
Population genetic patterns suggest a behavioural change in wild common frogs (Rana temporaria) following disease outbreaks (Ranavirus)Teacher AGF, Garner TWJ and Nichols RA
Mol Ecol vol. 18 (15), 3163-3172.
01-08-2009
Geographically localised bursts of ribosomal DNA mobility in the grasshopper Podisma pedestris.Veltsos P, Keller I and Nichols RA
Heredity (Edinb) vol. 103 (1), 54-61.
01-07-2009
European phylogeography of the common frog (Rana temporaria): routes of postglacial colonization into the British Isles, and evidence for an Irish glacial refugium.Teacher AGF, Garner TWJ and Nichols RA
Heredity (Edinb) vol. 102 (5), 490-496.
01-05-2009
Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus).Teacher AGF, Garner TWJ and Nichols RA
Plos One vol. 4 (2)
01-01-2009
2008
The inexorable spread of a newly arisen neo-Y chromosome.Veltsos P, Keller I and Nichols RA
Plos Genet vol. 4 (5)
30-05-2008
A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity (vol 96, pg 3, 1995)Balding DJ and Nichols RA
Genetica vol. 133 (1), 107-107.
01-05-2008
The frequency of rDNA variants within individuals provides evidence of population history and gene flow across a grasshopper hybrid zone.Keller I, Veltsos P and Nichols RA
Evolution vol. 62 (4), 833-844.
01-04-2008
The role of vicariance vs. dispersal in shaping genetic patterns in ocellated lizard species in the western MediterraneanPaulo OS, Pinheiro J, Miraldo A, Bruford MW, Jordan WC and Nichols RA
Mol Ecol vol. 17 (6), 1535-1551.
01-03-2008
2007
Landscape, habitat characteristics and the genetic population structure of two caddisfliesWilcock HR, Bruford MW, Nichols RA and Hildrew AG
Freshwater Biol vol. 52 (10), 1907-1929.
01-10-2007
DNA sequence variability in Oka vaccine isolatesBreuer J, Quinlivan M, Al Bassam M, Macdonald S, Nichols RA, Steinberg SP, La Russa P and Gershon AA
J Infect Dis vol. 196 (5), 801-802.
01-09-2007
Dates from the molecular clock: how wrong can we be?Pulquério MJF and Nichols RA
Trends Ecol Evol vol. 22 (4), 180-184.
01-04-2007
Transition-transversion bias is not universal: a counter example from grasshopper pseudogenes.Keller I, Bensasson D and Nichols RA
Plos Genet vol. 3 (2)
02-02-2007
Natural selection for rash-forming genotypes of the varicella-zoster vaccine virus detected within immunized human hostsQuinlivan ML, Gershon AA, Al Bassam MM, Steinberg SP, LaRussa P, Nichols RA and Breuer J
P Natl Acad Sci Usa vol. 104 (1), 208-212.
02-01-2007
2006
Genome-wide characterisation of Hepatitis B mutations involved in clinical outcomeSzmaragd C, Foster GR, Manica A, Bartholomeusz A, Nichols RA and Balloux F
Heredity vol. 97 (6), 389-397.
01-12-2006
Ribosomal DNA in the grasshopper Podisma pedestris: escape from concerted evolution.Keller I, Chintauan-Marquier IC, Veltsos P and Nichols RA
Genetics vol. 174 (2), 863-874.
01-10-2006
Morphological differentiation following experimental bottlenecks in the butterfly Bicyclus anynana (Nymphalidae)Saccheri IJ, Nichols RA and Brakefield PM
Biol J Linn Soc vol. 89 (1), 107-115.
01-09-2006
Natural selection of rash-forming genotypes of the varicella vaccine virus within humansQuinlivan ML, Gershon AA, Albassam MM, Steinberg SP, IaRussa P, Sharrar RA, Nichols RA and Breuer J
JOURNAL OF CLINICAL VIROLOGY. vol. 36, S23-S23.
01-08-2006
Vaccine Oka varicella-zoster virus genotypes are monomorphic in single vesicles and polymorphic in respiratory tract secretionsQuinlivan MA, Gershon AA, Nichols RA, La Russa P, Steinberg SP and Breuer J
J Infect Dis vol. 193 (7), 927-930.
01-04-2006
A novel approach to characterise pathogen candidate genetic polymorphisms involved in clinical outcomeSzmaragd C, Nichols RA and Balloux F
Infect Genet Evol vol. 6 (1), 38-45.
01-01-2006
Hepatitis B virus mutations involved in clinical outcomeSzmaragd C, Foster GR, Manica A, Bartholomeusz A, Nichols RA and Balloux F
Journal of Hepatology vol. 44, 400-400.
01-01-2006
2005
Recruitment, kin and the spatial genetic structure of a caddisfly Plectrocnemia conspersa in a southern English streamWilcock HR, Bruford MW, Hildrew AG and Nichols RA
Freshwater Biol vol. 50 (9), 1499-1514.
01-09-2005
Quantitative genetics focus issueNichols RA
Heredity, Springer Nature vol. 94 (3), 273-274.
24-02-2005
Genetic and Evolutionary Impacts of Climate ChangeHewitt GM and NICHOLS RA
In Climate Change and Biodiversity, Yale University Press 176-192. Editors: Lovejoy TE and Hannah L.
01-01-2005
2004
The origin and evolution of geminivirus-related DNA sequences in Nicotiana.Murad L, Bielawski JP, Matyasek R, Kovarík A, Nichols RA, Leitch AR and Lichtenstein CP
Heredity (Edinb) vol. 92 (4), 352-358.
01-04-2004
Molecular phylogeny and morphological change in the Psittacula parakeets.Groombridge JJ, Jones CG, Nichols RA, Carlton M and Bruford MW
Mol Phylogenet Evol vol. 31 (1), 96-108.
01-04-2004
Using molecular markers with high mutation rates to obtain estimates of relative population size and to distinguish the effects of gene flow and mutation: a demonstration using data from endemic Mauritian skinks.Nichols RA and Freeman KLM
Mol Ecol vol. 13 (4), 775-787.
01-04-2004
2003
An analysis of consanguinity and social structure within the UK Asian population using microsatellite data.Overall ADJ, Ahmad M, Thomas MG and Nichols RA
Ann Hum Genet vol. 67 (Pt 6), 525-537.
01-11-2003
Genetic population structure and neighbourhood population size estimates of the caddisfly Plectrocnemia conspersaWilcock HR, Nichols RA and Hildrew AG
Freshwater Biol vol. 48 (10), 1813-1824.
01-10-2003
Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis.Hinchliffe SJ, Isherwood KE, Stabler RA, Prentice MB, Rakin A, Nichols RA, Oyston PCF, Hinds J, Titball RW and Wren BW
Genome Res vol. 13 (9), 2018-2029.
01-09-2003
2002
A molecular phylogeny of African kestrels with reference to divergence across the Indian OceanGroombridge JJ, Jones CG, Bayes MK, van Zyl AJ, Carrillo J, Nichols RA and Bruford MW
Mol Phylogenet Evol vol. 25 (2), 267-277.
01-11-2002
Y genetic data support the Neolithic demic diffusion modelChikhi L, Nichols RA, Barbujani G and Beaumont MA
P Natl Acad Sci Usa vol. 99 (17), 11008-11013.
20-08-2002
The effect of reproductive compensation on recessive disorders within consanguineous human populations.Overall ADJ, Ahmad M and Nichols RA
Heredity (Edinb) vol. 88 (6), 474-479.
01-06-2002
Using nested clade analysis to assess the history of colonization and the persistence of populations of an Iberian LizardPaulo OS, Jordan WC, Bruford MW and Nichols RA
Mol Ecol vol. 11 (4), 809-819.
01-04-2002
Patterns of colonization in a metapopulation of grey sealsGaggiotti OE, Jones F, Lee WM, Amos W, Harwood J and Nichols RA
Nature vol. 416 (6879), 424-427.
28-03-2002
Phylogenetic analysis of varicella-zoster virus: Evidence of intercontinental spread of genotypes and recombinationMuir WB, Nichols R and Breuer J
J Virol vol. 76 (4), 1971-1979.
01-02-2002
A molecular phylogeny of African kestrels with reference to divergence across the Indian OceanGroombridge JJ, Jones CG, Bayes MK, van Zyl AJ, Carrillo J, Nichols RA and Bruford MW
Molecular Phylogenetics and Evolution, Elsevier/Science Direct vol. 25, 267-277.
01-01-2002
The double origin of Iberian peninsular chameleonsPaulo OS, Pinto I, Bruford MW, Jordan WC and Nichols RA
Biol J Linn Soc vol. 75 (1), 1-7.
01-01-2002
2001
Culex pipiens in London Underground tunnels: differentiation between surface and subterranean populationsByrne K and Nichols RA
Heredity vol. 82 (1), 7-15.
25-12-2001
Microsatellites for the net-spinning caddisfly Plectrocnemia conspersa (Polycentropodidae)Wilcock HR, Hildrew AG, Nichols RA and Bruford MW
Mol Ecol Notes vol. 1 (4), 318-319.
01-12-2001
A method for distinguishing consanguinity and population substructure using multilocus genotype dataOverall ADJ and Nichols RA
Mol Biol Evol vol. 18 (11), 2048-2056.
01-11-2001
The persistence of Pliocene populations through the Pleistocene climatic cycles: evidence from the phylogeography of an Iberian lizardPaulo OS, Dias C, Bruford MW, Jordan WC and Nichols RA
P Roy Soc Lond B Bio vol. 268 (1476), 1625-1630.
07-08-2001
Gene trees and species trees are not the same.Nichols R
Trends Ecol Evol vol. 16 (7), 358-364.
01-07-2001
Genetic differentiation of a European caddisfly: past and present gene flow among fragmented larval habitats.Wilcock HR, Hildrew AG and Nichols RA
Mol Ecol vol. 10 (7), 1821-1834.
01-07-2001
Mating patterns, relatedness and the basis of natal philopatry in the brown long-eared bat, Plecotus auritusBurland TM, Barratt EM, Nichols RA and Racey PA
Mol Ecol vol. 10 (5), 1309-1321.
01-05-2001
Evaluating the severity of the population bottleneck in the Mauritius kestrel Falco punctatus from ringing records using MCMC estimationGroombridge JJ, Bruford MW, Jones CG and Nichols RA
J Anim Ecol vol. 70 (3), 401-409.
01-05-2001
Effects of bottlenecks on quantitative genetic variation in the butterfly Bicyclus anynanaSaccheri IJ, Nichols RA and Brakefield PM
Genet Res vol. 77 (2), 167-181.
01-04-2001
Sustaining genetic variation in a small population: evidence from the Mauritius kestrelNichols RA, Bruford MW and Groombridge JJ
Molecular Ecology vol. 10 (3), 593-602.
01-03-2001
2000
‘Ghost’ alleles of the Mauritius kestrelGroombridge JJ, Jones CG, Bruford MW and Nichols RA
Nature, Springer Nature vol. 403 (6770), 616-616.
01-02-2000
1999
Minisatellite mutational processes reduce F-st estimatesFlint J, Bond J, Rees DC, Boyce AJ, Roberts-Thomson JM, Excoffier L, Clegg JB, Beaumont MA, Nichols RA and Harding RM
Hum Genet vol. 105 (6), 567-576.
01-12-1999
Inbreeding of bottlenecked butterfly populations: Estimation using the likelihood of changes in marker allele frequenciesSaccheri IJ, Wilson IJ, Nichols RA, Bruford MW and Brakefield PM
Genetics vol. 151 (3), 1053-1063.
01-03-1999
Culex pipiens in London Underground tunnels: differentiation between surface and subterranean populations.Byrne K and Nichols RA
Heredity (Edinb) vol. 82 ( Pt 1), 7-15.
01-01-1999
The introduction of molecular genetic techniques into forensic scienceNICHOLS RA
In Biotechnology, The Science & The Business, Harwood Academic Publishers 649-657. Editors: RE SDMMC.
01-01-1999
1997
Genetic differentiation between and within strains of the saw-toothed grain beetle, Oryzaephilus surinamensis (Coleoptera: Silvanidae) at RAPD loci.Brown RJ, Malcolm CA, Mason PL and Nichols RA
Insect Mol Biol vol. 6 (3), 285-289.
01-08-1997
Significant genetic correlations among Caucasians at forensic DNA loci.Balding DJ and Nichols RA
Heredity (Edinb) vol. 78 ( Pt 6), 583-589.
01-06-1997
Population structure and insecticidal control of the sawtoothed grain beetle (Coleoptera: Silvanidae) under simulated field conditionsMason PL, Brown RJ and Nichols RA
J Econ Entomol vol. 90 (1), 27-37.
01-02-1997
1996
Evaluating loci for use in the genetic analysis of population structureBeaumont MA and Nichols RA
P Roy Soc Lond B Bio vol. 263 (1377), 1619-1626.
22-12-1996
Severe inbreeding depression and rapid fitness rebound in the butterfly Bicyclus anynana (Satyridae)Saccheri IJ, Brakefield PM and Nichols RA
Evolution vol. 50 (5), 2000-2013.
01-10-1996
Spatial patterns of genetic variation generated by different forms of dispersal during range expansionIbrahim KM, Nichols RA and Hewitt GM
Heredity vol. 77, 282-291.
01-09-1996
Is it ancient or modern history that we can read in the genes?NICHOLS RA
In Aspects of The Genesis and Maintenance of Biological Diversity, Oxford University Press 69-87. Editors: Hochberg ME, Clobert J and Barbault R.
01-01-1996
Assessing relatedness and evolutionary divergence: why the genetic evidence alone is not enough.NICHOLS RA
In Molecular Genetic Approaches in Conservation, Oxford University Press 365-382. Editors: RK STW.
01-01-1996
Population genetics of STR loci in Caucasians.Balding DJ, Greenhalgh M and Nichols RA
Int J Legal Med vol. 108 (6), 300-305.
01-01-1996
1995
A METHOD FOR QUANTIFYING DIFFERENTIATION BETWEEN POPULATIONS AT MULTI-ALLELIC LOCI AND ITS IMPLICATIONS FOR INVESTIGATING IDENTITY AND PATERNITYBALDING D and NICHOLS R
Genetica, Springer Verlag vol. 96 (1-2), 3-12.
01-06-1995
PHILOPATRY IN THE ALPINE GRASSHOPPER, PODISMA-PEDESTRIS - A NOVEL EXPERIMENTAL AND ANALYTICAL METHODMASON PL, NICHOLS RA and HEWITT GM
Ecol Entomol vol. 20 (2), 137-145.
01-05-1995
A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity.Balding DJ and Nichols RA
Genetica vol. 96 (1-2), 3-12.
01-01-1995
A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternityBalding DJ and Nichols RA
In Human Identification: The Use of Dna Markers, Springer Nature 3-12.
01-01-1995
1994
SOME CAUSES FOR CONCERN ABOUT DNA PROFILES - COMMENTBALDING DJ, DONNELLY P and NICHOLS RA
Stat Sci vol. 9 (2), 248-251.
01-05-1994
THE GENETIC CONSEQUENCES OF LONG-DISTANCE DISPERSAL DURING COLONIZATIONNICHOLS RA and HEWITT GM
Heredity vol. 72, 312-317.
01-03-1994
DNA profile match probability calculation: how to allow for population stratification, relatedness, database selection and single bands.Balding DJ and Nichols RA
Forensic Sci Int vol. 64 (2-3), 125-140.
01-02-1994
Comment: Some causes for concern about DNA profilesBalding DJ, Donnelly P and Nichols RA
Statistical Science vol. 9 (2), 248-252.
01-01-1994
1992
Detecting gene conversion: primate visual pigment genes.Balding DJ, Nichols RA and Hunt DM
Proc Biol Sci vol. 249 (1326), 275-280.
22-09-1992
SEXUAL PREFERENCE AND GENETIC CORRELATIONSNICHOLS RA and BUTLIN RK
Trends Ecol Evol vol. 7 (1), 29-30.
01-01-1992
1991
Effects of population structure on DNA fingerprint analysis in forensic science.Nichols RA and Balding DJ
Heredity (Edinb) vol. 66 ( Pt 2), 297-302.
01-04-1991
1989
THE FRAGMENTATION OF TENSION ZONES IN SPARSELY POPULATED AREASNICHOLS RA
Am Nat vol. 134 (6), 969-977.
01-12-1989
MITOCHONDRIAL-DNA CLUES TO GOPHER TORTOISE DISPERSALNICHOLS RA
Trends Ecol Evol vol. 4 (7), 192-193.
01-07-1989
SPERM PRECEDENCE AND HOMOGAMY ACROSS A HYBRID ZONE IN THE ALPINE GRASSHOPPER PODISMA-PEDESTRISHEWITT GM, MASON P and NICHOLS RA
Heredity vol. 62, 343-353.
01-06-1989
DOES RUNAWAY SEXUAL SELECTION WORK IN FINITE POPULATIONSNICHOLS RA and BUTLIN RK
J Evolution Biol vol. 2 (4), 299-313.
01-01-1989
1988
ECOLOGICAL GENETICS - 1868 AND ALL THAT FOR MAGICICADAHEWITT GM, NICHOLS RA and RITCHIE MG
Nature vol. 336 (6196), 206-207.
17-11-1988
GENETIC AND ECOLOGICAL DIFFERENTIATION ACROSS A HYBRID ZONENICHOLS RA and HEWITT GM
Ecol Entomol vol. 13 (1), 39-49.
01-02-1988
1987
HOMOGAMY IN A HYBRID ZONE IN THE ALPINE GRASSHOPPER PODISMA-PEDESTRISHEWITT GM, NICHOLS RA and BARTON NH
Heredity vol. 59, 457-466.
01-12-1987
1986
POPULATION-STRUCTURE AND THE SHAPE OF A CHROMOSOMAL CLINE BETWEEN 2 RACES OF PODISMA-PEDESTRIS (ORTHOPTERA, ACRIDIDAE)NICHOLS RA and HEWITT GM
Biol J Linn Soc vol. 29 (4), 301-316.
01-12-1986
HETEROCHROMATIN READJUSTING CHIASMA DISTRIBUTION IN 2 SPECIES OF THE GENUS ARCYPTERA - THE EFFECT AMONG INDIVIDUALS AND POPULATIONSDELATORRE J, LOPEZFERNANDEZ C, NICHOLS R and GOSALVEZ J
Heredity vol. 56, 177-184.
01-04-1986
Grants
Grants of specific relevance to the Centre for Evolutionary and Functional GenomicsPredicting risk to non-native trees species from potential threats in the UKRichard Nichols
£13,521 DEFRA Department for Environment, Food & Rural Affairs (DEFRA)
01-10-2023 - 31-03-2025
PhD studentship - Assessing the risk to plant health in the UK from future Agrilus invasionsRichard Nichols
£79,125 DEFRA Department for Environment, Food & Rural Affairs (DEFRA)
01-10-2020 - 31-03-2024
A high-throughput platform for assembling genome data: the SaphyrStephen Rossiter, Richard Nichols and Chema Martin Duran
£271,357 NERC Natural Environment Research Council
01-10-2019 - 31-03-2020
NERC DTP CASE Award - Charlotte Ford studentship top upRichard Nichols
£4,000 CEFAS Centre for Environment Fisheries and Aquaculture Science
01-09-2019 - 31-08-2023
GCRF Ethiopian project with KewRichard Nichols and Adrian Larkeryd
£329,633 BBSRC Biotechnology and Biological Sciences Research Council
01-04-2019 - 30-09-2021