Dr Roman Arguello
Lecturer in Genetics, Genomics and Fundamental Cell Biology
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
evolutionary genomics, sensory neurobiology, evo-devo, behaviour
Interests
Our lab uses evolutionary/population genomic and neurobiology approaches to investigate the genetic and cellular changes underlying the diversification of sensory systems. These aims link with related topics in evolutionary biology such as the roles that local adaptation, gene flow, and demographic histories play in shaping genetic and phenotypic changes.Publications of specific relevance to the Centre for Evolutionary and Functional Genomics
2024
Bontonou G, Saint-Leandre B, Kafle T, Tess B, Hassan A, Antonio Sánchez-Alcañiz J and Arguello JR (2024). Evolution of chemosensory tissues and cells across ecologically diverse Drosophilids. Nature Communications, Nature Research vol. 15 (1047) 05-02-2024
2023
Takagi S, Sancer G, Abuin L, Stupski SD, Arguello JR, Prieto-Godino LL, Stern DL, Cruchet S, Álvarez-Ocaña R, Wienecke CFR, van Breugel F, Jeanne JM, Auer TO and Benton R (2023). Sensory neuron population expansion enhances odor tracking without sensitizing projection neurons. Nature Communications, Nature Research vol. 4 (09-22), 2023.09.15.556782-2023.09.15.556782. 15-09-2023
2022
Auer TO, Álvarez-Ocaña R, Cruchet S, Benton R and Arguello JR (2022). Copy number changes in co-expressed odorant receptor genes enable selection for sensory differences in drosophilid species. Nature Ecology & Evolution, Springer Nature vol. 6 (9), 1343-1353. 21-07-2022
2021
Arguello JR, Abuin L, Armida J, Mika K, Chai PC and Benton R (2021). Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring and functional determinants. eLife, eLife vol. 10, e63036-e63036. 05-03-2021
2020
Auer TO, Khallaf MA, Silbering AF, Zappia G, Ellis K, Álvarez-Ocaña R, Arguello JR, Hansson BS, Jefferis GSXE, Caron SJC, Knaden M and Benton R (2020). Olfactory receptor and circuit evolution promote host specialization. Nature, Springer Nature vol. 579 (7799), 402-408. 04-03-2020
2019
Arguello JR, Laurent S and Clark AG (2019). Demographic History of the Human Commensal Drosophila melanogaster. Genome Biology and Evolution, Oxford University Press (OUP) vol. 11 (3), 844-854. 31-01-2019
2017
Arguello JR and Benton R (2017). Open questions: Tackling Darwin’s “instincts”: the genetic basis of behavioral evolution. BMC Biology, Springer Nature vol. 15 (1) 03-04-2017
Early AM, Arguello JR, Cardoso-Moreira M, Gottipati S, Grenier JK and Clark AG (2017). Survey of Global Genetic Diversity Within the Drosophila Immune System. Genetics, Oxford University Press (OUP) vol. 205 (1), 353-366. 01-01-2017
2016
Prieto-Godino LL, Rytz R, Bargeton B, Abuin L, Arguello JR, Peraro MD and Benton R (2016). Olfactory receptor pseudo-pseudogenes. Nature, Springer Nature vol. 539 (7627), 93-97. 24-10-2016
Arguello JR, Cardoso-Moreira M, Grenier JK, Gottipati S, Clark AG and Benton R (2016). Extensive local adaptation within the chemosensory system following Drosophila melanogaster’s global expansion. Nature Communications, Springer Nature vol. 7 (1) 13-06-2016
Cardoso-Moreira M, Arguello JR, Gottipati S, Harshman LG, Grenier JK and Clark AG (2016). Evidence for the fixation of gene duplications by positive selection in Drosophila. Genome Research, Cold Spring Harbor Laboratory vol. 26 (6), 787-798. 12-04-2016
2015
Grenier JK, Arguello JR, Moreira MC, Gottipati S, Mohammed J, Hackett SR, Boughton R, Greenberg AJ and Clark AG (2015). Global Diversity Lines–A Five-Continent Reference Panel of Sequenced Drosophila melanogaster Strains. G3: Genes, Genomes, Genetics, Oxford University Press (OUP) vol. 5 (4), 593-603. 01-04-2015
2012
Cardoso-Moreira M, Arguello JR and Clark AG (2012). Mutation spectrum of Drosophila CNVs revealed by breakpoint sequencing. Genome Biology, Springer Nature vol. 13 (12) 01-01-2012
2011
Arguello JR and Connallon T (2011). Gene Duplication and Ectopic Gene Conversion in Drosophila. Genes, MDPI vol. 2 (1), 131-151. 11-02-2011
2009
Arguello JR, Zhang Y, Kado T, Fan C, Zhao R, Innan H, Wang W and Long M (2009). Recombination Yet Inefficient Selection along the Drosophila melanogaster Subgroup's Fourth Chromosome. Molecular Biology and Evolution, Oxford University Press (OUP) vol. 27 (4), 848-861. 14-12-2009
2008
Yang S, Arguello JR, Li X, Ding Y, Zhou Q, Chen Y, Zhang Y, Zhao R, Brunet F, Peng L, Long M and Wang W (2008). Repetitive Element-Mediated Recombination as a Mechanism for New Gene Origination in Drosophila. PLOS Genetics, Public Library of Science (PLoS) vol. 4 (1) 01-01-2008
2007
McBride CS, Arguello JR and O'Meara BC (2007). Five Drosophila Genomes Reveal Nonneutral Evolution and the Signature of Host Specialization in the Chemoreceptor Superfamily. Genetics, Oxford University Press (OUP) vol. 177 (3), 1395-1416. 01-11-2007
Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B, Aguade M, Akashi H, Anderson WW, et al. (2007). Evolution of genes and genomes on the Drosophila phylogeny. Nature, Springer Nature vol. 450 (7167), 203-218. 01-11-2007
Arguello JR, Fan C, Wang W and Long M (2007). Origination of Chimeric Genes through DNA-Level Recombination. Gene and Protein Evolution 01-01-2007
2006
Arguello JR, Chen Y, Yang S, Wang W and Long M (2006). Origination of an X-Linked Testes Chimeric Gene by Illegitimate Recombination in Drosophila. PLOS Genetics, Public Library of Science (PLoS) vol. 2 (5) 01-05-2006
2005
HOFFMAN EA, KOLM N, BERGLUND A, ARGUELLO JR and JONES AG (2005). Genetic structure in the coral‐reef‐associated Banggai cardinalfish, Pterapogon kauderni. Molecular Ecology, Wiley vol. 14 (5), 1367-1375. 29-03-2005