Dr Matteo Fumagalli
Senior Lecturer in Genetics
deputy Head of Biology Department
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
population genetics, bioinformatics, machine learning, evolutionary biology, human evolution
Interests
I am interested in the inference of demographic and adaptive events from genomic data in both model and non-model species, and in their association with phenotypic and functional variation. I also develop statistical methods and implement software for the analysis of high-throughput DNA sequencing data.Publications
Publications of specific relevance to the Centre for Evolutionary and Functional Genomics2024
Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta CoalescentKorfmann K, Sellinger TPP, Freund F, Fumagalli M and Tellier A
Peer Community Journal, Peer Community In vol. 4
18-03-2024
2023
The genomic footprint of social stratification in admixing American populationsMas-Sandoval A, Mathieson S and Fumagalli M
Elife, Elife vol. 12
01-12-2023
ngsJulia: population genetic analysis of next-generation DNA sequencing data with Julia language.Mas-Sandoval A, Jin C, Fracassetti M and Fumagalli M
F1000research vol. 11, 126-126.
14-07-2023
Deep Learning in Population GeneticsKorfmann K, Gaggiotti OE and Fumagalli M
Genome Biology and Evolution, Oxford University Press (Oup) vol. 15 (2)
23-01-2023
2022
HMMploidy: inference of ploidy levels from short-read sequencing dataSoraggi S, Rhodes J, Altinkaya I, Tarrant O, Balloux F, Fisher MC and Fumagalli M
Peer Community Journal, Peer Community In vol. 2
14-10-2022
Fast and accurate estimation of multidimensional site frequency spectra from low-coverage high-throughput sequencing dataMas-Sandoval A, Pope NS, Nielsen KN, Altinkaya I, Fumagalli M and Korneliussen TS
Gigascience vol. 11
17-05-2022
Disentangling Signatures of Selection before and after European Colonization in Latin AmericansMendoza-Revilla J, Chacón-Duque JC, Fuentes-Guajardo M, Ormond L, Wang K, Hurtado M, Villegas V, Granja V, Acuña-Alonzo V, Jaramillo C, Arias W, Barquera R, Gómez-ValdCrossed D Sign©s J, Villamil-Ramírez H, Silva De Cerqueira CC, Badillo Rivera KM, Nieves-Colón MA, Gignoux CR, Wojcik GL, Moreno-Estrada ADS, et al.
Molecular Biology and Evolution vol. 39 (4)
19-04-2022
2021
Detecting adaptive introgression in human evolution using convolutional neural networksGower G, Picazo PI, Fumagalli M and Racimo F
Elife, Elife vol. 10
25-05-2021
Distinguishing between recent balancing selection and incomplete sweep using deep neural networksIsildak U, Stella A and Fumagalli M
Molecular Ecology Resources, Wiley vol. 21 (8), 2706-2718.
05-04-2021
2020
Detecting loci under natural selection from temporal genomic data of selfing populationsFumagalli M
Peer Community in Evolutionary Biology, Peer Community In
26-10-2020
Inference of natural selection from ancient DNADehasque M, Ávila‐Arcos MC, Díez‐del‐Molino D, Fumagalli M, Guschanski K, Lorenzen ED, Malaspinas A, Marques‐Bonet T, Martin MD, Murray GGR, Papadopulos AST, Therkildsen NO, Wegmann D, Dalén L and Foote AD
Evolution Letters, Oxford University Press (Oup) vol. 4 (2), 94-108.
01-04-2020
2019
ImaGene: a convolutional neural network to quantify natural selection from genomic dataTorada L, Lorenzon L, Beddis A, Isildak U, Pattini L, Mathieson S and Fumagalli M
Bmc Bioinformatics, Springer Nature vol. 20 (Suppl 9)
01-11-2019
Genetic diversity of CHC22 clathrin impacts its function in glucose metabolismFumagalli M, Camus SM, Diekmann Y, Burke A, Camus MD, Norman PJ, Joseph A, Abi-Rached L, Benazzo A, Rasteiro R, Mathieson I, Topf M, Parham P, Thomas MG and Brodsky FM
Elife, Elife vol. 8
04-06-2019
Phenotypic sexual dimorphism is associated with genomic signatures of resolved sexual conflictWright AE, Rogers TF, Fumagalli M, Cooney CR and Mank JE
Molecular Ecology, Wiley vol. 28 (11), 2860-2871.
01-06-2019
ngsLD: evaluating linkage disequilibrium using genotype likelihoodsFox EA, Wright AE, Fumagalli M and Vieira FG
Bioinformatics, Oxford University Press (Oup) vol. 35 (19), 3855-3856.
23-03-2019
A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in EurasiaAdhikari K, Mendoza-Revilla J, Sohail A, Fuentes-Guajardo M, Lampert J, Chacón-Duque JC, Hurtado M, Villegas V, Granja V, Acuña-Alonzo V, Jaramillo C, Arias W, Lozano RB, Everardo P, Gómez-Valdés J, Villamil-Ramírez H, Silva de Cerqueira CC, Hunemeier T, Ramallo V, Schuler-Faccini L, et al.
Nature Communications, Springer Nature vol. 10 (1)
21-01-2019
2018
Recent Asian origin of chytrid fungi causing global amphibian declinesO'Hanlon SJ, Rieux A, Farrer RA, Rosa GM, Waldman B, Bataille A, Kosch TA, Murray KA, Brankovics B, Fumagalli M, Martin MD, Wales N, Alvarado-Rybak M, Bates KA, Berger L, Böll S, Brookes L, Clare F, Courtois EA, Cunningham AA, et al.
Science, American Association For The Advancement of Science (Aaas) vol. 360 (6389), 621-627.
11-05-2018
Male‐biased gene expression resolves sexual conflict through the evolution of sex‐specific genetic architectureWright AE, Fumagalli M, Cooney CR, Bloch NI, Vieira FG, Buechel SD, Kolm N and Mank JE
Evolution Letters, Oxford University Press (Oup) vol. 2 (2), 52-61.
01-04-2018
Genome-wide analyses of the Bemisia tabaci species complex reveal contrasting patterns of admixture and complex demographic historiesElfekih S, Etter P, Tay WT, Fumagalli M, Gordon K, Johnson E and De Barro P
Plos One, Public Library of Science (Plos) vol. 13 (1)
24-01-2018
2017
Oral microbiomes from hunter‐gatherers and traditional farmers reveal shifts in commensal balance and pathogen load linked to dietLassalle F, Spagnoletti M, Fumagalli M, Shaw L, Dyble M, Walker C, Thomas MG, Migliano AB and Balloux F
Molecular Ecology, Wiley vol. 27 (1), 182-195.
14-12-2017
Survival and divergence in a small group: The extraordinary genomic history of the endangered Apennine brown bear stragglersBenazzo A, Trucchi E, Cahill JA, Delser PM, Mona S, Fumagalli M, Bunnefeld L, Cornetti L, Ghirotto S, Girardi M, Ometto L, Panziera A, Rota-Stabelli O, Zanetti E, Karamanlidis A, Groff C, Paule L, Gentile L, Vilà C, Vicario S, et al.
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 114 (45), e9589-e9597.
24-10-2017
Natural Selection Associated With Infectious DiseasesFumagalli M and Balloux F
In On Human Nature: Biology, Psychology, Ethics, Politics, and Religion 177-191.
01-01-2017
Chapter 11 Natural Selection Associated With Infectious DiseasesFumagalli M and Balloux F
In On Human Nature, Elsevier 177-191.
01-01-2017
2016
Archaic Adaptive Introgression in TBX15/WARS2Racimo F, Gokhman D, Fumagalli M, Ko A, Hansen T, Moltke I, Albrechtsen A, Carmel L, Huerta-Sánchez E and Nielsen R
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 34 (3), 509-524.
21-12-2016
Genome-culture coevolution promotes rapid divergence of killer whale ecotypesFoote AD, Vijay N, Ávila-Arcos MC, Baird RW, Durban JW, Fumagalli M, Gibbs RA, Hanson MB, Korneliussen TS, Martin MD, Robertson KM, Sousa VC, Vieira FG, Vinař T, Wade P, Worley KC, Excoffier L, Morin PA, Gilbert MTP and Wolf JBW
Nature Communications, Springer Nature vol. 7 (1)
31-05-2016
2015
Tracking the origins of Yakutian horses and the genetic basis for their fast adaptation to subarctic environmentsLibrado P, Der Sarkissian C, Ermini L, Schubert M, Jónsson H, Albrechtsen A, Fumagalli M, Yang MA, Gamba C, Seguin-Orlando A, Mortensen CD, Petersen B, Hoover CA, Lorente-Galdos B, Nedoluzhko A, Boulygina E, Tsygankova S, Neuditschko M, Jagannathan V, Thèves C, et al.
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 112 (50), e6889-e6897.
23-11-2015
Evolutionary Genomics and Conservation of the Endangered Przewalski’s HorseDer Sarkissian C, Ermini L, Schubert M, Yang MA, Librado P, Fumagalli M, Jónsson H, Bar-Gal GK, Albrechtsen A, Vieira FG, Petersen B, Ginolhac A, Seguin-Orlando A, Magnussen K, Fages A, Gamba C, Lorente-Galdos B, Polani S, Steiner C, Neuditschko M, et al.
Current Biology, Elsevier vol. 25 (19), 2577-2583.
24-09-2015
Greenlandic Inuit show genetic signatures of diet and climate adaptationFumagalli M, Moltke I, Grarup N, Racimo F, Bjerregaard P, Jørgensen ME, Korneliussen TS, Gerbault P, Skotte L, Linneberg A, Christensen C, Brandslund I, Jørgensen T, Huerta-Sánchez E, Schmidt EB, Pedersen O, Hansen T, Albrechtsen A and Nielsen R
Science, American Association For The Advancement of Science (Aaas) vol. 349 (6254), 1343-1347.
18-09-2015
Improving the estimation of genetic distances from Next‐Generation Sequencing dataVieira FG, Lassalle F, Korneliussen TS and Fumagalli M
Biological Journal of The Linnean Society, Oxford University Press (Oup) vol. 117 (1), 139-149.
30-03-2015
Erratum: The origin and evolution of maize in the Southwestern United Statesda Fonseca RR, Smith BD, Wales N, Cappellini E, Skoglund P, Fumagalli M, Samaniego JA, Carøe C, Ávila-Arcos MC, Hufnagel DE, Korneliussen TS, Vieira FG, Jakobsson M, Arriaza B, Willerslev E, Nielsen R, Hufford MB, Albrechtsen A, Ross-Ibarra J and Gilbert MTP
Nature Plants, Springer Nature vol. 1 (1)
14-01-2015
The origin and evolution of maize in the Southwestern United Statesda Fonseca RR, Smith BD, Wales N, Cappellini E, Skoglund P, Fumagalli M, Samaniego JA, Carøe C, Ávila-Arcos MC, Hufnagel DE, Korneliussen TS, Vieira FG, Jakobsson M, Arriaza B, Willerslev E, Nielsen R, Hufford MB, Albrechtsen A, Ross-Ibarra J and Gilbert MTP
Nature Plants, Springer Nature vol. 1 (1)
08-01-2015
2014
Uncovering the Genetic History of the Present-Day Greenlandic PopulationMoltke I, Fumagalli M, Korneliussen TS, Crawford JE, Bjerregaard P, Jørgensen ME, Grarup N, Gulløv HC, Linneberg A, Pedersen O, Hansen T, Nielsen R and Albrechtsen A
American Journal of Human Genetics, Elsevier vol. 96 (1), 54-69.
31-12-2014
Prehistoric genomes reveal the genetic foundation and cost of horse domesticationSchubert M, Jónsson H, Chang D, Der Sarkissian C, Ermini L, Ginolhac A, Albrechtsen A, Dupanloup I, Foucal A, Petersen B, Fumagalli M, Raghavan M, Seguin-Orlando A, Korneliussen TS, Velazquez AMV, Stenderup J, Hoover CA, Rubin C-J, Alfarhan AH, Alquraishi SA, et al.
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 111 (52), e5661-e5669.
15-12-2014
Speciation with gene flow in equids despite extensive chromosomal plasticityJónsson H, Schubert M, Seguin-Orlando A, Ginolhac A, Petersen L, Fumagalli M, Albrechtsen A, Petersen B, Korneliussen TS, Vilstrup JT, Lear T, Myka JL, Lundquist J, Miller DC, Alfarhan AH, Alquraishi SA, Al-Rasheid KAS, Stagegaard J, Strauss G, Bertelsen MF, et al.
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 111 (52), 18655-18660.
01-12-2014
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetesMoltke I, Grarup N, Jørgensen ME, Bjerregaard P, Treebak JT, Fumagalli M, Korneliussen TS, Andersen MA, Nielsen TS, Krarup NT, Gjesing AP, Zierath JR, Linneberg A, Wu X, Sun G, Jin X, Al-Aama J, Wang J, Borch-Johnsen K, Pedersen O, et al.
Nature, Springer Nature vol. 512 (7513), 190-193.
18-06-2014
Human genome variability, natural selection and infectious diseasesFumagalli M and Sironi M
Current Opinion in Immunology, Elsevier vol. 30, 9-16.
29-05-2014
Population Genomics Reveal Recent Speciation and Rapid Evolutionary Adaptation in Polar BearsLiu S, Lorenzen ED, Fumagalli M, Li B, Harris K, Xiong Z, Zhou L, Korneliussen TS, Somel M, Babbitt C, Wray G, Li J, He W, Wang Z, Fu W, Xiang X, Morgan CC, Doherty A, O’Connell MJ, McInerney JO, et al.
Cell, Elsevier vol. 157 (4), 785-794.
01-05-2014
ngsTools: methods for population genetics analyses from next-generation sequencing dataFumagalli M, Vieira FG, Linderoth T and Nielsen R
Bioinformatics, Oxford University Press (Oup) vol. 30 (10), 1486-1487.
23-01-2014
2013
Assessing the Effect of Sequencing Depth and Sample Size in Population Genetics InferencesFumagalli M
Plos One, Public Library of Science (Plos) vol. 8 (11)
18-11-2013
Quantifying Population Genetic Differentiation from Next-Generation Sequencing DataFumagalli M, Vieira FG, Korneliussen TS, Linderoth T, Huerta-Sánchez E, Albrechtsen A and Nielsen R
Genetics, Oxford University Press (Oup) vol. 195 (3), 979-992.
01-11-2013
Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimationVieira FG, Fumagalli M, Albrechtsen A and Nielsen R
Genome Research, Cold Spring Harbor Laboratory vol. 23 (11), 1852-1861.
15-08-2013
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horseOrlando L, Ginolhac A, Zhang G, Froese D, Albrechtsen A, Stiller M, Schubert M, Cappellini E, Petersen B, Moltke I, Johnson PLF, Fumagalli M, Vilstrup JT, Raghavan M, Korneliussen T, Malaspinas A-S, Vogt J, Szklarczyk D, Kelstrup CD, Vinther J, et al.
Nature, Springer Nature vol. 499 (7456), 74-78.
26-06-2013
A Scan for Human-Specific Relaxation of Negative Selection Reveals Unexpected Polymorphism in Proteasome GenesSomel M, Sayres MAW, Jordan G, Huerta-Sanchez E, Fumagalli M, Ferrer-Admetlla A and Nielsen R
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 30 (8), 1808-1815.
22-05-2013
Long‐Standing Balancing Selection in the THBS4 Gene: Influence on Sex‐Specific Brain Expression and Gray Matter Volumes in Alzheimer DiseaseCagliani R, Guerini FR, Rubio‐Acero R, Baglio F, Forni D, Agliardi C, Griffanti L, Fumagalli M, Pozzoli U, Riva S, Calabrese E, Sikora M, Casals F, Comi GP, Bresolin N, Cáceres M, Clerici M and Sironi M
Human Mutation, Hindawi vol. 34 (5), 743-753.
02-04-2013
Crohn's Disease Loci Are Common Targets of Protozoa-Driven SelectionCagliani R, Pozzoli U, Forni D, Cassinotti A, Fumagalli M, Giani M, Fichera M, Lombardini M, Ardizzone S, Asselta R, de Franchis R, Riva S, Biasin M, Comi GP, Bresolin N, Clerici M and Sironi M
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 30 (5), 1077-1087.
06-02-2013
2012
An evolutionary history of the selectin gene cluster in humansFumagalli M, Fracassetti M, Cagliani R, Forni D, Pozzoli U, Comi GP, Marini F, Bresolin N, Clerici M and Sironi M
Heredity, Springer Nature vol. 109 (2), 117-126.
02-05-2012
A Trans-Specific Polymorphism in ZC3HAV1 Is Maintained by Long-Standing Balancing Selection and May Confer Susceptibility to Multiple SclerosisCagliani R, Guerini FR, Fumagalli M, Riva S, Agliardi C, Galimberti D, Pozzoli U, Goris A, Dubois B, Fenoglio C, Forni D, Sanna S, Zara I, Pitzalis M, Zoledziewska M, Cucca F, Marini F, Comi GP, Scarpini E, Bresolin N, et al.
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 29 (6), 1599-1613.
06-01-2012
2011
Variants in SNAP25 are targets of natural selection and influence verbal performances in womenCagliani R, Riva S, Marino C, Fumagalli M, D’Angelo MG, Riva V, Comi GP, Pozzoli U, Forni D, Cáceres M, Bresolin N, Clerici M and Sironi M
Cellular and Molecular Life Sciences, Springer Nature vol. 69 (10), 1705-1715.
23-12-2011
Evolutionary genetic dissection of human interferonsManry J, Laval G, Patin E, Fornarino S, Itan Y, Fumagalli M, Sironi M, Tichit M, Bouchier C, Casanova J-L, Barreiro LB and Quintana-Murci L
Journal of Experimental Medicine, Rockefeller University Press vol. 208 (13), 2747-2759.
12-12-2011
Correction: Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human EvolutionFumagalli M, Sironi M, Pozzoli U, Ferrer-Admetlla A, Pattini L and Nielsen R
Plos Genetics, Public Library of Science (Plos) vol. 7 (11)
21-11-2011
Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human EvolutionFumagalli M, Sironi M, Pozzoli U, Ferrer-Admettla A, Pattini L and Nielsen R
Plos Genetics, Public Library of Science (Plos) vol. 7 (11)
01-11-2011
Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysisCagliani R, Fumagalli M, Guerini FR, Riva S, Galimberti D, Comi GP, Agliardi C, Scarpini E, Pozzoli U, Forni D, Caputo D, Asselta R, Biasin M, Paraboschi EM, Bresolin N, Clerici M and Sironi M
Human Genetics, Springer Nature vol. 131 (1), 87-97.
07-07-2011
A POSITIVELY SELECTED APOBEC3H HAPLOTYPE IS ASSOCIATED WITH NATURAL RESISTANCE TO HIV‐1 INFECTIONCagliani R, Riva S, Fumagalli M, Biasin M, Caputo SL, Mazzotta F, Piacentini L, Pozzoli U, Bresolin N, Clerici M and Sironi M
Evolution, Wiley vol. 65 (11), 3311-3322.
28-06-2011
Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolvingCagliani R, Riva S, Pozzoli U, Fumagalli M, Comi GP, Bresolin N, Clerici M and Sironi M
Bmc Ecology and Evolution, Springer Nature vol. 11 (1)
17-06-2011
An Evolutionary Analysis of RAC2 Identifies Haplotypes Associated with Human Autoimmune DiseasesSironi M, Guerini FR, Agliardi C, Biasin M, Cagliani R, Fumagalli M, Caputo D, Cassinotti A, Ardizzone S, Zanzottera M, Bolognesi E, Riva S, Kanari Y, Miyazawa M and Clerici M
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 28 (12), 3319-3329.
16-06-2011
2010
Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infectionCagliani R, Riva S, Biasin M, Fumagalli M, Pozzoli U, Caputo SL, Mazzotta F, Piacentini L, Bresolin N, Clerici M and Sironi M
Human Molecular Genetics, Oxford University Press (Oup) vol. 19 (23), 4705-4714.
15-09-2010
Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 geneCagliani R, Fumagalli M, Biasin M, Piacentini L, Riva S, Pozzoli U, Bonaglia MC, Bresolin N, Clerici M and Sironi M
Human Genetics, Springer Nature vol. 128 (6), 577-588.
02-09-2010
The landscape of human genes involved in the immune response to parasitic wormsFumagalli M, Pozzoli U, Cagliani R, Comi GP, Bresolin N, Clerici M and Sironi M
Bmc Ecology and Evolution, Springer Nature vol. 10 (1)
31-08-2010
Population Genetics of IFIH1: Ancient Population Structure, Local Selection, and Implications for Susceptibility to Type 1 DiabetesFumagalli M, Cagliani R, Riva S, Pozzoli U, Biasin M, Piacentini L, Comi GP, Bresolin N, Clerici M and Sironi M
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 27 (11), 2555-2566.
10-06-2010
Fine mapping of AHI1 as a schizophrenia susceptibility gene: from association to evolutionary evidenceTorri F, Akelai A, Lupoli S, Sironi M, Amann‐Zalcenstein D, Fumagalli M, Dal Fiume C, Ben‐Asher E, Kanyas K, Cagliani R, Cozzi P, Trombetti G, Lievers LS, Salvi E, Orro A, Beckmann JS, Lancet D, Kohn Y, Milanesi L, Ebstein RB, et al.
The Faseb Journal, Wiley vol. 24 (8), 3066-3082.
06-04-2010
Polymorphisms in the CPB2 Gene Are Maintained by Balancing Selection and Result in Haplotype-Preferential Splicing of Exon 7Cagliani R, Fumagalli M, Riva S, Pozzoli U, Fracassetti M, Bresolin N, Comi GP and Sironi M
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 27 (8), 1945-1954.
17-03-2010
Response to Wilson et al.Fumagalli M, Cagliani R, Pozzoli U and Sironi M
American Journal of Human Genetics, Elsevier vol. 86 (3), 493-495.
01-03-2010
Genome-Wide Identification of Susceptibility Alleles for Viral Infections through a Population Genetics ApproachFumagalli M, Pozzoli U, Cagliani R, Comi GP, Bresolin N, Clerici M and Sironi M
Plos Genetics, Public Library of Science (Plos) vol. 6 (2)
19-02-2010
Genetic variability in the ACE gene region surrounding the Alu I/D polymorphism is maintained by balancing selection in human populationsCagliani R, Fumagalli M, Riva S, Pozzoli U, Comi GP, Bresolin N and Sironi M
Pharmacogenetics and Genomics, Wolters Kluwer vol. 20 (2), 131-134.
01-02-2010
The role of protozoa-driven selection in shaping human genetic variabilityPozzoli U, Fumagalli M, Cagliani R, Comi GP, Bresolin N, Clerici M and Sironi M
Trends in Genetics, Elsevier vol. 26 (3), 95-99.
25-01-2010
Balancing selection in the extended MHC region maintains a subset of alleles with opposite risk profile for different autoimmune diseasesCagliani R, Riva S, Fumagalli M, Pozzoli U, Comi GP, Bresolin N, Clerici M and Sironi M
Genome Biology, Springer Nature vol. 11 (Suppl 1)
01-01-2010
2009
A population genetics study of the Familial Mediterranean Fever gene: evidence of balancing selection under an overdominance regimeFumagalli M, Cagliani R, Pozzoli U, Riva S, Comi GP, Menozzi G, Bresolin N and Sironi M
Genes & Immunity, Springer Nature vol. 10 (8), 678-686.
13-08-2009
Diverse Evolutionary Histories for β-adrenoreceptor Genes in HumansCagliani R, Fumagalli M, Pozzoli U, Riva S, Comi GP, Torri F, Macciardi F, Bresolin N and Sironi M
American Journal of Human Genetics, Elsevier vol. 85 (1), 64-75.
01-07-2009
A complex selection signature at the human AVPR1B geneCagliani R, Fumagalli M, Pozzoli U, Riva S, Cereda M, Comi GP, Pattini L, Bresolin N and Sironi M
Bmc Ecology and Evolution, Springer Nature vol. 9 (1)
01-06-2009
Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditionsFumagalli M, Pozzoli U, Cagliani R, Comi GP, Riva S, Clerici M, Bresolin N and Sironi M
Journal of Experimental Medicine, Rockefeller University Press vol. 206 (6), 1395-1408.
25-05-2009
2008
Widespread balancing selection and pathogen-driven selection at blood group antigen genesFumagalli M, Cagliani R, Pozzoli U, Riva S, Comi GP, Menozzi G, Bresolin N and Sironi M
Genome Research, Cold Spring Harbor Laboratory vol. 19 (2), 199-212.
07-11-2008
Both selective and neutral processes drive GC content evolution in the human genomePozzoli U, Menozzi G, Fumagalli M, Cereda M, Comi GP, Cagliani R, Bresolin N and Sironi M
Bmc Ecology and Evolution, Springer Nature vol. 8 (1)
27-03-2008
The signature of long-standing balancing selection at the human defensin β-1 promoterCagliani R, Fumagalli M, Riva S, Pozzoli U, Comi GP, Menozzi G, Bresolin N and Sironi M
Genome Biology, Springer Nature vol. 9 (9)
01-01-2008
Grants
Grants of specific relevance to the Centre for Evolutionary and Functional GenomicsUsing Population Genetics to Address Metabolic Health Disparities in East London's Diverse Ethnic PopulationsMoneeza Kalhan Siddiqui, Segun Fatumo, Matteo Fumagalli and Sarah Finer
£74,125 Barts and the London Charity
24-02-2025 - 23-02-2026
NSFDEB-NERC: Machine learning tools to discover balancing selection in genomes from spatial and temporal autocorrelationsMatteo Fumagalli
£121,751 NERC Natural Environment Research Council
01-12-2023 - 30-11-2026
Synthetic clinical data for underrepresented populations: a UK-France allianceMatteo Fumagalli, Moneeza Kalhan Siddiqui and Venet Osmani
£9,500 DSIT Department for Science, Innovation and Technology
01-01-2025 - 31-03-2025
Generative adversarial networks for demographic inferences of nonmodel species from genomic dataMatteo Fumagalli
£76,699 NERC Natural Environment Research Council
13-02-2023 - 12-10-2023