Prof Richard Nichols
Professor of Evolutionary Genetics
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
Population Genetics, Evolutionary Genomics, Bayesian Analysis, Conservation, Range Expansion, Invasive Species
Interests
My work combines the collection of genetic data with the development of new analytical methods. I interpret genetic patterns to ask how populations have spread or contracted, merged or been fragmented and how they have been shaped by natural selection.I apply this approach to a wide diversity of organisms:
Trees: I work with colleagues at Kew to counteract threats to British trees, encompassing projects to identify the genetic basis of resistance to invasive diseases of Ash trees (with Richard Buggs) and exploiting phylogenetic information to anticipate threats from invasive beetles (with Laura Kelly).
Viruses: with Trent Garner (Institute of Zoology) I study the spread of wildlife viruses affecting fish, reptiles, and amphibians. I ask why they have recently appeared in new locations & species.
Human cancer cells: I work with Trevor Graham (Barts Cancer Institute) using experiments on cancer cell lines to ask if we can identify strategies to retard resistance to chemotherapy, by exploiting evolutionary insights.
Model organisms: conducting experimental evolution, for example on Drosophila fruit flies (with Bill Sherwin in UNSW), I ask if there are flaws or omissions in our current evolutionary models.
Crops: I am a member of a project with (The Natural Resources Institute and Kew) to identify crop varieties that will be resilient to climate change in Ethiopia.
Publications
Publications of specific relevance to the Centre for Biodiversity and Sustainability2024
da Silva SSM, Faizullah L, Guignard MS, Orcen N, Ruban AV, Rudall PJ, Trimmer M, Nichols RA, Leitch IJ and Leitch AR (2024). Nitrogen and phosphorus interactions at a 21 nitrogen:1 phosphorus Redfield‐like ratio impact growth and seed yield in wheat (Triticum aestivum L.). Food and Energy Security, Wiley vol. 13 (4) 30-07-2024
2023
White OW, Biswas MK, Abebe WM, Dussert Y, Kebede F, Nichols RA, Buggs RJA, Demissew S, Woldeyes F, Papadopulos AST, Schwarzacher T, Heslop‐Harrison PJS, Wilkin P and Borrell JS (2023). Maintenance and expansion of genetic and trait variation following domestication in a clonal crop. Molecular Ecology, Wiley vol. 32 (15), 4165-4180. 02-06-2023
Becher H and Nichols RA (2023). Assembly‐free quantification of vagrant DNA inserts. Molecular Ecology Resources, Wiley vol. 23 (5), 1002-1013. 15-02-2023
2022
Ford CE, Brookes LM, Skelly E, Sergeant C, Jordine T, Balloux F, Nichols RA and Garner TWJ (2022). Non-Lethal Detection of Frog Virus 3-Like (RUK13) and Common Midwife Toad Virus-Like (PDE18) Ranaviruses in Two UK-Native Amphibian Species. Viruses, MDPI vol. 14 (12) 25-11-2022
Lau Y, Oamen HP, Grogg M, Parfenova I, Saarikangas J, Hannay R, Nichols RA, Hilvert D, Barral Y and Caudron F (2022). Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell. Current Biology, Elsevier vol. 32 (5), 963-974.e7. 31-01-2022
Marquardt J, Blanckaert A, Nichols RA, Ansell SW, Ruhsam M, Hollingsworth PM, Metzler D, Schneider H and Leitch AR (2022). Cyto-nuclear incompatibilities across a bluebell hybrid zone in northern Spain do not prevent genome-wide introgression of neutral markers. Evolutionary Journal of the Linnean Society, Oxford University Press (OUP) vol. 1 (1), kzac003-kzac003. 01-01-2022
2021
Gathercole LAP, Nocchi G, Brown N, Coker TLR, Plumb WJ, Stocks JJ, Nichols RA, Denman S and Buggs RJA (2021). Evidence for the Widespread Occurrence of Bacteria Implicated in Acute Oak Decline from Incidental Genetic Sampling. Forests vol. 12 (12), 1683-1683. 01-12-2021
Stevens MCA, Faulkner SC, Wilke ABB, Beier JC, Vasquez C, Petrie W, Fry H, Nichols RA, Verity R and Le Comber SC (2021). Spatially clustered count data provide more efficient search strategies in invasion biology and disease control. Ecol Appl, Ecological Society of America, e2329-e2329. 22-03-2021
2020
Martinez-Ruiz C, Pracana R, Stolle E, Paris CI, Nichols RA and Wurm Y (2020). Correction: Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants. eLife, eLife Sciences Publications Ltd vol. 9 09-11-2020
Martinez-Ruiz C, Pracana R, Stolle E, Paris CI, Nichols RA and Wurm Y (2020). Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants. eLife, eLife vol. 9 10-08-2020
2019
Stocks J, Metheringham C, Plumb W, Lee S, Kelly L, Nichols R and Buggs R (2019). Genomic basis of European ash tree resistance to ash dieback fungus. Nature Ecology and Evolution, Nature Research 18-11-2019
BORRELL J, ZOHREN J, Nichols R and Buggs R (2019). Genomic assessment of local adaptation in dwarf birch to inform assisted gene flow. Evolutionary Applications: evolutionary approaches to environmental, biomedical and socio-economic issues, Wiley 20-10-2019
Duffus ALJ, Garner TWJ, Nichols RA, Standridge JP and Earl JE (2019). Modelling Ranavirus Transmission in Populations of Common Frogs (Rana temporaria) in the United Kingdom. Viruses, MDPI vol. 11 (6) 15-06-2019
Price SJ, Leung WTM, Owen CJ, Puschendorf R, Sergeant C, Cunningham AA, Balloux F, Garner TWJ and Nichols RA (2019). Effects of historic and projected climate change on the range and impacts of an emerging wildlife disease. Global Change Biology, Wiley vol. 25 (8), 2648-2660. 09-05-2019
Guignard MS, Crawley MJ, Kovalenko D, Nichols RA, Trimmer M, Leitch AR and Leitch IJ (2019). Interactions between plant genome size, nutrients and herbivory by rabbits, molluscs and insects on a temperate grassland. Proceedings of the Royal Society B, The Royal Society vol. 286 (1899) 20-03-2019
Jan HU, Guan M, Yao M, Liu W, Wei D, Abbadi A, Zheng M, He X, Chen H, Guan C, Nichols RA, Snowdon RJ, Hua W and Qian L (2019). Genome-wide haplotype analysis improves trait predictions in Brassica napus hybrids. Plant Science vol. 283, 157-164. 13-03-2019
2018
Borrell JS, Wang N, Nichols RA and Buggs RJA (2018). Genetic diversity maintained among fragmented populations of a tree undergoing range contraction. Heredity (Edinb) vol. 121 (4), 304-318. 01-10-2018
2017
Pracana R, Priyam A, Levantis I, Nichols RA and Wurm Y (2017). The fire ant social chromosome supergene variant Sb shows low diversity but high divergence from SB. Molecular Ecology, Wiley vol. 26 (11), 2864-2879. 01-04-2017
Mijangos JL, Holleley CE, Nichols RA, Towers IN, Jovanoski Z, Sidhu HS, Watt S, Adamack AT and Sherwin WB (2017). Genetic linkage to explain genetic variation. 01-01-2017
2016
Price SJ, Garner TW, Cunningham AA, Langton TE and Nichols RA (2016). Reconstructing the emergence of a lethal infectious disease of wildlife supports a key role for spread through translocations by humans. Proc Biol Sci vol. 283 (1839) 28-09-2016
Verity R and Nichols RA (2016). Estimating the Number of Subpopulations (K) in Structured Populations. Genetics: a periodical record of investigations bearing on heredity and variation, Genetics Society of America vol. 203 (4), 1827-1839. 01-08-2016
Verity R and Nichols RA (2016). Documentation for MAVERICK software: Version 1.0. Genetics vol. 203 (4) 01-08-2016
Verity R and Nichols RA (2016). File s1: Derivation of evidence estimators and model comparison statistics. Genetics vol. 203 (4) 01-08-2016
Zohren J, Wang N, Kardailsky I, Borrell JS, Joecker A, Nichols RA and Buggs RJA (2016). Unidirectional diploid-tetraploid introgression among British birch trees with shifting ranges shown by RAD markers. Molecular Ecology, Wiley: 12 months 11-05-2016
Guignard MS, Nichols RA, Knell RJ, Macdonald A, Romila C-A, Trimmer M, Leitch IJ and LEITCH AR (2016). Genome size and ploidy influence angiosperm species’ biomass under nitrogen and phosphorus limitation. New Phytologist, John Wiley & Sons, Inc 15-02-2016
Jan HU, Abbadi A, Lücke S, Nichols RA and Snowdon RJ (2016). Genomic Prediction of Testcross Performance in Canola (Brassica napus). PLOS ONE, Public Library of Science (PLoS) vol. 11 (1) 29-01-2016
2015
Kelly LJ, Renny‐Byfield S, Pellicer J, Macas J, Novák P, Neumann P, Lysak MA, Day PD, Berger M, Fay MF, Nichols RA, Leitch AR and Leitch IJ (2015). Analysis of the giant genomes of Fritillaria (Liliaceae) indicates that a lack of DNA removal characterizes extreme expansions in genome size. New Phytologist, Wiley vol. 208 (2), 596-607. 08-06-2015
Weinert LA, Depledge DP, Kundu S, Gershon AA, Nichols RA, Balloux F, Welch JJ and Breuer J (2015). Rates of Vaccine Evolution Show Strong Effects of Latency: Implications for Varicella Zoster Virus Epidemiology. Molecular Biology and Evolution, Oxford University Press (OUP) vol. 32 (4), 1020-1028. 06-01-2015
2014
Duffus ALJ, Nichols RA and Garner TWJ (2014). Detection of a frog virus 3-like ranavirus in native and introduced amphibians in the United Kingdom in 2007 and 2008. Herpetological Review vol. 45 (4), 608-610. 01-12-2014
Duffus ALJ, Nichols RA and Garner TWJ (2014). Experimental evidence in support of single host maintenance of a multihost pathogen. Ecosphere, Wiley vol. 5 (11), 1-11. 01-11-2014
Price SJ, Garner TWJ, Nichols RA, Balloux F, Ayres C, de Alba AM-C and Bosch J (2014). Collapse of Amphibian Communities Due to an Introduced Ranavirus. Current Biology, Elsevier vol. 24 (21), 2586-2591. 16-10-2014
Verity R and Nichols RA (2014). What is genetic differentiation, and how should we measure it--GST, D, neither or both? Mol Ecol vol. 23 (17), 4216-4225. 01-09-2014
Wang N, Borrell JS, Bodles WJA, Kuttapitiya A, Nichols RA and Buggs RJA (2014). Molecular footprints of the Holocene retreat of dwarf birch in Britain. Mol Ecol vol. 23 (11), 2771-2782. 01-06-2014
Chintauan-Marquier IC, Amédégnato C, Nichols RA, Pompanon F, Grandcolas P and Desutter-Grandcolas L (2014). Inside the Melanoplinae: new molecular evidence for the evolutionary history of the Eurasian Podismini (Orthoptera: Acrididae). Mol Phylogenet Evol vol. 71, 224-233. 01-02-2014
Verity R, Stevenson MD, Rossmo DK, Nichols RA and Le Comber SC (2014). Spatial targeting of infectious disease control: Identifying multiple, unknown sources. Methods in Ecology and Evolution vol. 5 (7), 647-655. 01-01-2014
Holleley CE, Nichols RA, Whitehead MR, Adamack AT, Gunn MR and Sherwin WB (2014). Testing single-sample estimators of effective population size in genetically structured populations. CONSERVATION GENETICS vol. 15 (1), 23-35. 01-01-2014
De Silva DR, Nichols R and Elgar G (2014). Purifying selection in deeply conserved human enhancers is more consistent than in coding sequences. PLoS One vol. 9 (7) 01-01-2014
Wang N, Borrell JS, Bodles WJA, Kuttapitiya A, Nichols RA and Buggs RJA (2014). Molecular footprints of the Holocene retreat of dwarf birch in Britain. Molecular Ecology 01-01-2014
2013
Hoban S, Arntzen JW, Bertorelle G, Bryja J, Fernandes M, Frith K, Gaggiotti O, Galbusera P, Godoy JA, Hauffe HC, Rus Hoelzel A, Nichols RA, Pérez-Espona S, Primmer C, Russo IRM, Segelbacher G, Siegismund HR, Sihvonen M, Sjögren-Gulve P, Vernesi C, et al. (2013). Conservation Genetic Resources for Effective Species Survival (ConGRESS): Bridging the divide between conservation research and practice. Journal for Nature Conservation vol. 21 (6), 433-437. 01-12-2013
Duffus ALJ, Nichols RA and Garner TWJ (2013). Investigations into the life history stages of the common frog (Rana temporaria) affected by an amphibian ranavirus in the United Kingdom. Herpetological Review vol. 44 (2), 260-263. 01-12-2013
Depledge DP, Kundu S, Jensen NJ, Gray ER, Jones M, Steinberg S, Gershon A, Kinchington PR, Schmid DS, Balloux F, Nichols RA and Breuer J (2013). Deep Sequencing of Viral Genomes Provides Insight into the Evolution and Pathogenesis of Varicella Zoster Virus and Its Vaccine in Humans. Molecular Biology and Evolution, Oxford University Press (OUP) vol. 31 (2), 397-409. 25-10-2013
Renny-Byfield S, Kovarik A, Kelly LJ, Macas J, Novak P, Chase MW, Nichols RA, Pancholi MR, Grandbastien M-A and Leitch AR (2013). Diploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences. Plant J vol. 74 (5), 829-839. 01-06-2013
Renny-Byfield S, Kovarik A, Kelly LJ, MacAs J, Novak P, Chase MW, Nichols RA, Pancholi MR, Grandbastien MA and Leitch AR (2013). Diploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences. Plant Journal vol. 74 (5), 829-839. 01-06-2013
Nichols RA, Butlin RK and Bruford MW (2013). Godfrey M Hewitt (1940-2013): highlights in Heredity from a career in evolutionary genetics. Heredity (Edinb) vol. 110 (5), 405-406. 01-05-2013
Abbott R, Albach D, Ansell S, Arntzen JW, Baird SJE, Bierne N, Boughman JW, Brelsford A, Buerkle CA, Buggs R, Butlin RK, Dieckmann U, Eroukhmanoff F, Grill A, Cahan SH, Hermansen JS, Hewitt G, Hudson AG, Jiggins C, Jones J, et al. (2013). Hybridization and speciation. JOURNAL OF EVOLUTIONARY BIOLOGY vol. 26 (2), 229-246. 01-01-2013
Matyasek R, Renny-Byfield S, Fulnecek J, Macas J, Grandbastien M-A, Nichols R, Leitch A and Kovarik A (2013). Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids. BMC GENOMICS, BIOMED CENTRAL LTD vol. 13 (722) 01-01-2013
Hoban SM, Hauffe HC, Perez-Espona S, Arntzen JW, Bertorelle G, Bryja J, Frith K, Gaggiotti OE, Galbusera P, Godoy JA, Hoelzel AR, Nichols RA, Primmer CR, Russo I-R, Segelbacher G, Siegismund HR, Sihvonen M, Vernesi C, Vila C and Bruford MW (2013). Bringing genetic diversity to the forefront of conservation policy and management. CONSERVATION GENETICS RESOURCES vol. 5 (2), 593-598. 01-01-2013
Hoban S, Arntzen JW, Bertorelle G, Bryja J, Fernandes M, Frith K, Gaggiotti O, Galbusera P, Godoy JA, Hauffe HC, Rus Hoelzel A, Nichols RA, Pérez-Espona S, Primmer C, Russo I-RM, Segelbacher G, Siegismund HR, Sihvonen M, Sjögren-Gulve P, Vernesi C, et al. (2013). Conservation Genetic Resources for Effective Species Survival (ConGRESS): Bridging the divide between conservation research and practice. Journal for Nature Conservation 01-01-2013
Hoban S, Gaggiotti O, Bertorelle G, Arntzen P, Bryja J, Fernandes M, Frith K, Galbusera P, Godoy JA, Hauffe HC, Hoelzel R, Nichols R, Perez-Espona S, Primmer C, Russo I-RM, Segelbacher G, Siegismund HR, Sihvonen M, Sjoegren-Gulve P, Vernesi C, et al. (2013). Sample Planning Optimization Tool for conservation and population Genetics (SPOTG): a software for choosing the appropriate number of markers and samples. METHODS IN ECOLOGY AND EVOLUTION vol. 4 (3), 299-303. 01-01-2013
2012
Renny-Byfield S, Kovařík A, Chester M, Nichols RA, Macas J, Novák P and Leitch AR (2012). Independent, rapid and targeted loss of highly repetitive DNA in natural and synthetic allopolyploids of Nicotiana tabacum. PLoS One vol. 7 (5) 01-01-2012
2011
Renny-Byfield S, Chester M, Kovařík A, Le Comber SC, Grandbastien M-A, Deloger M, Nichols RA, Macas J, Novák P, Chase MW and Leitch AR (2011). Next generation sequencing reveals genome downsizing in allotetraploid Nicotiana tabacum, predominantly through the elimination of paternally derived repetitive DNAs. Mol Biol Evol vol. 28 (10), 2843-2854. 01-10-2011
Dewar RC, Sherwin WB, Thomas E, Holleley CE and Nichols RA (2011). Predictions of single-nucleotide polymorphism differentiation between two populations in terms of mutual information. Mol Ecol vol. 20 (15), 3156-3166. 01-08-2011
Johnson LJ, Cotton JA, Lichtenstein CP, Elgar GS, Nichols RA, Polly PD and Le Comber SC (2011). Stops making sense: translational trade-offs and stop codon reassignment. BMC Evol Biol vol. 11 29-07-2011
Kanda RK, Quinlivan ML, Gershon AA, Nichols RA and Breuer J (2011). Population diversity in batches of the varicella Oka vaccine. VACCINE vol. 29 (17), 3293-3298. 12-04-2011
Nichols RA, Averbeck KT, Poulsen AG, al Bassam MM, Cabral F, Aaby P and Breuer J (2011). Household size is critical to varicella-zoster virus transmission in the tropics despite lower viral infectivity. Epidemics vol. 3 (1), 12-18. 01-03-2011
Holleley CE, Nichols RA, Whitehead MR, Gunn MR, Gupta J and Sherwin WB (2011). Induced dispersal in wildlife management: experimental evaluation of the risk of hybrid breakdown and the benefit of hybrid vigor in the F1 generation. CONSERV GENET vol. 12 (1), 31-40. 01-02-2011
Brown RM, Jordan WC, Faulkes CG, Jones CG, Bugoni L, Tatayah V, Palma RL and Nichols RA (2011). Phylogenetic relationships in Pterodroma petrels are obscured by recent secondary contact and hybridization. PLoS One vol. 6 (5) 01-01-2011
2010
Brown RM, Nichols RA, Faulkes CG, Jones CG, Bugoni L, Tatayah V, Gottelli D and Jordan WC (2010). Range expansion and hybridization in Round Island petrels (Pterodroma spp.): evidence from microsatellite genotypes. Mol Ecol vol. 19 (15), 3157-3170. 01-08-2010
2009
Teacher AGF, Garner TWJ and Nichols RA (2009). Population genetic patterns suggest a behavioural change in wild common frogs (Rana temporaria) following disease outbreaks (Ranavirus). MOL ECOL vol. 18 (15), 3163-3172. 01-08-2009
Veltsos P, Keller I and Nichols RA (2009). Geographically localised bursts of ribosomal DNA mobility in the grasshopper Podisma pedestris. Heredity (Edinb) vol. 103 (1), 54-61. 01-07-2009
Teacher AGF, Garner TWJ and Nichols RA (2009). European phylogeography of the common frog (Rana temporaria): routes of postglacial colonization into the British Isles, and evidence for an Irish glacial refugium. Heredity (Edinb) vol. 102 (5), 490-496. 01-05-2009
Teacher AGF, Garner TWJ and Nichols RA (2009). Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus). PLoS One vol. 4 (2) 01-01-2009
2008
Veltsos P, Keller I and Nichols RA (2008). The inexorable spread of a newly arisen neo-Y chromosome. PLoS Genet vol. 4 (5) 30-05-2008
Balding DJ and Nichols RA (2008). A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity (vol 96, pg 3, 1995). GENETICA vol. 133 (1), 107-107. 01-05-2008
Keller I, Veltsos P and Nichols RA (2008). The frequency of rDNA variants within individuals provides evidence of population history and gene flow across a grasshopper hybrid zone. Evolution vol. 62 (4), 833-844. 01-04-2008
Paulo OS, Pinheiro J, Miraldo A, Bruford MW, Jordan WC and Nichols RA (2008). The role of vicariance vs. dispersal in shaping genetic patterns in ocellated lizard species in the western Mediterranean. MOL ECOL vol. 17 (6), 1535-1551. 01-03-2008
2007
Wilcock HR, Bruford MW, Nichols RA and Hildrew AG (2007). Landscape, habitat characteristics and the genetic population structure of two caddisflies. FRESHWATER BIOL vol. 52 (10), 1907-1929. 01-10-2007
Breuer J, Quinlivan M, Al Bassam M, Macdonald S, Nichols RA, Steinberg SP, La Russa P and Gershon AA (2007). DNA sequence variability in Oka vaccine isolates. J INFECT DIS vol. 196 (5), 801-802. 01-09-2007
Pulquério MJF and Nichols RA (2007). Dates from the molecular clock: how wrong can we be? Trends Ecol Evol vol. 22 (4), 180-184. 01-04-2007
Keller I, Bensasson D and Nichols RA (2007). Transition-transversion bias is not universal: a counter example from grasshopper pseudogenes. PLoS Genet vol. 3 (2) 02-02-2007
Quinlivan ML, Gershon AA, Al Bassam MM, Steinberg SP, LaRussa P, Nichols RA and Breuer J (2007). Natural selection for rash-forming genotypes of the varicella-zoster vaccine virus detected within immunized human hosts. P NATL ACAD SCI USA vol. 104 (1), 208-212. 02-01-2007
2006
Szmaragd C, Foster GR, Manica A, Bartholomeusz A, Nichols RA and Balloux F (2006). Genome-wide characterisation of Hepatitis B mutations involved in clinical outcome. HEREDITY vol. 97 (6), 389-397. 01-12-2006
Keller I, Chintauan-Marquier IC, Veltsos P and Nichols RA (2006). Ribosomal DNA in the grasshopper Podisma pedestris: escape from concerted evolution. Genetics vol. 174 (2), 863-874. 01-10-2006
Saccheri IJ, Nichols RA and Brakefield PM (2006). Morphological differentiation following experimental bottlenecks in the butterfly Bicyclus anynana (Nymphalidae). BIOL J LINN SOC vol. 89 (1), 107-115. 01-09-2006
Quinlivan ML, Gershon AA, Albassam MM, Steinberg SP, IaRussa P, Sharrar RA, Nichols RA and Breuer J (2006). Natural selection of rash-forming genotypes of the varicella vaccine virus within humans. 01-08-2006
Quinlivan MA, Gershon AA, Nichols RA, La Russa P, Steinberg SP and Breuer J (2006). Vaccine Oka varicella-zoster virus genotypes are monomorphic in single vesicles and polymorphic in respiratory tract secretions. J INFECT DIS vol. 193 (7), 927-930. 01-04-2006
Szmaragd C, Nichols RA and Balloux F (2006). A novel approach to characterise pathogen candidate genetic polymorphisms involved in clinical outcome. INFECT GENET EVOL vol. 6 (1), 38-45. 01-01-2006
Szmaragd C, Foster GR, Manica A, Bartholomeusz A, Nichols RA and Balloux F (2006). Hepatitis B virus mutations involved in clinical outcome. JOURNAL OF HEPATOLOGY vol. 44, 400-400. 01-01-2006
2005
Wilcock HR, Bruford MW, Hildrew AG and Nichols RA (2005). Recruitment, kin and the spatial genetic structure of a caddisfly Plectrocnemia conspersa in a southern English stream. FRESHWATER BIOL vol. 50 (9), 1499-1514. 01-09-2005
Nichols RA (2005). Quantitative genetics focus issue. Heredity, Springer Nature vol. 94 (3), 273-274. 24-02-2005
Hewitt GM and NICHOLS RA (2005). Genetic and Evolutionary Impacts of Climate Change. Climate Change and Biodiversity , Editors: Lovejoy TE and Hannah L. 176-192. 01-01-2005
2004
Murad L, Bielawski JP, Matyasek R, Kovarík A, Nichols RA, Leitch AR and Lichtenstein CP (2004). The origin and evolution of geminivirus-related DNA sequences in Nicotiana. Heredity (Edinb) vol. 92 (4), 352-358. 01-04-2004
Groombridge JJ, Jones CG, Nichols RA, Carlton M and Bruford MW (2004). Molecular phylogeny and morphological change in the Psittacula parakeets. Mol Phylogenet Evol vol. 31 (1), 96-108. 01-04-2004
Nichols RA and Freeman KLM (2004). Using molecular markers with high mutation rates to obtain estimates of relative population size and to distinguish the effects of gene flow and mutation: a demonstration using data from endemic Mauritian skinks. Mol Ecol vol. 13 (4), 775-787. 01-04-2004
2003
Overall ADJ, Ahmad M, Thomas MG and Nichols RA (2003). An analysis of consanguinity and social structure within the UK Asian population using microsatellite data. Ann Hum Genet vol. 67 (Pt 6), 525-537. 01-11-2003
Wilcock HR, Nichols RA and Hildrew AG (2003). Genetic population structure and neighbourhood population size estimates of the caddisfly Plectrocnemia conspersa. FRESHWATER BIOL vol. 48 (10), 1813-1824. 01-10-2003
Hinchliffe SJ, Isherwood KE, Stabler RA, Prentice MB, Rakin A, Nichols RA, Oyston PCF, Hinds J, Titball RW and Wren BW (2003). Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis. Genome Res vol. 13 (9), 2018-2029. 01-09-2003
2002
Groombridge JJ, Jones CG, Bayes MK, van Zyl AJ, Carrillo J, Nichols RA and Bruford MW (2002). A molecular phylogeny of African kestrels with reference to divergence across the Indian Ocean. MOL PHYLOGENET EVOL vol. 25 (2), 267-277. 01-11-2002
Chikhi L, Nichols RA, Barbujani G and Beaumont MA (2002). Y genetic data support the Neolithic demic diffusion model. P NATL ACAD SCI USA vol. 99 (17), 11008-11013. 20-08-2002
Overall ADJ, Ahmad M and Nichols RA (2002). The effect of reproductive compensation on recessive disorders within consanguineous human populations. Heredity (Edinb) vol. 88 (6), 474-479. 01-06-2002
Paulo OS, Jordan WC, Bruford MW and Nichols RA (2002). Using nested clade analysis to assess the history of colonization and the persistence of populations of an Iberian Lizard. MOL ECOL vol. 11 (4), 809-819. 01-04-2002
Gaggiotti OE, Jones F, Lee WM, Amos W, Harwood J and Nichols RA (2002). Patterns of colonization in a metapopulation of grey seals. NATURE vol. 416 (6879), 424-427. 28-03-2002
Muir WB, Nichols R and Breuer J (2002). Phylogenetic analysis of varicella-zoster virus: Evidence of intercontinental spread of genotypes and recombination. J VIROL vol. 76 (4), 1971-1979. 01-02-2002
Groombridge JJ, Jones CG, Bayes MK, van Zyl AJ, Carrillo J, Nichols RA and Bruford MW (2002). A molecular phylogeny of African kestrels with reference to divergence across the Indian Ocean. MOLECULAR PHYLOGENETICS AND EVOLUTION, Elsevier/Science Direct vol. 25, 267-277. 01-01-2002
Paulo OS, Pinto I, Bruford MW, Jordan WC and Nichols RA (2002). The double origin of Iberian peninsular chameleons. BIOL J LINN SOC vol. 75 (1), 1-7. 01-01-2002
2001
Byrne K and Nichols RA (2001). Culex pipiens in London Underground tunnels: differentiation between surface and subterranean populations. Heredity vol. 82 (1), 7-15. 25-12-2001
Wilcock HR, Hildrew AG, Nichols RA and Bruford MW (2001). Microsatellites for the net-spinning caddisfly Plectrocnemia conspersa (Polycentropodidae). MOL ECOL NOTES vol. 1 (4), 318-319. 01-12-2001
Overall ADJ and Nichols RA (2001). A method for distinguishing consanguinity and population substructure using multilocus genotype data. MOL BIOL EVOL vol. 18 (11), 2048-2056. 01-11-2001
Paulo OS, Dias C, Bruford MW, Jordan WC and Nichols RA (2001). The persistence of Pliocene populations through the Pleistocene climatic cycles: evidence from the phylogeography of an Iberian lizard. P ROY SOC LOND B BIO vol. 268 (1476), 1625-1630. 07-08-2001
Nichols R (2001). Gene trees and species trees are not the same. Trends Ecol Evol vol. 16 (7), 358-364. 01-07-2001
Wilcock HR, Hildrew AG and Nichols RA (2001). Genetic differentiation of a European caddisfly: past and present gene flow among fragmented larval habitats. Mol Ecol vol. 10 (7), 1821-1834. 01-07-2001
Burland TM, Barratt EM, Nichols RA and Racey PA (2001). Mating patterns, relatedness and the basis of natal philopatry in the brown long-eared bat, Plecotus auritus. MOL ECOL vol. 10 (5), 1309-1321. 01-05-2001
Groombridge JJ, Bruford MW, Jones CG and Nichols RA (2001). Evaluating the severity of the population bottleneck in the Mauritius kestrel Falco punctatus from ringing records using MCMC estimation. J ANIM ECOL vol. 70 (3), 401-409. 01-05-2001
Saccheri IJ, Nichols RA and Brakefield PM (2001). Effects of bottlenecks on quantitative genetic variation in the butterfly Bicyclus anynana. GENET RES vol. 77 (2), 167-181. 01-04-2001
Nichols RA, Bruford MW and Groombridge JJ (2001). Sustaining genetic variation in a small population: evidence from the Mauritius kestrel. MOLECULAR ECOLOGY vol. 10 (3), 593-602. 01-03-2001
2000
Groombridge JJ, Jones CG, Bruford MW and Nichols RA (2000). ‘Ghost’ alleles of the Mauritius kestrel. Nature, Springer Nature vol. 403 (6770), 616-616. 01-02-2000
1999
Flint J, Bond J, Rees DC, Boyce AJ, Roberts-Thomson JM, Excoffier L, Clegg JB, Beaumont MA, Nichols RA and Harding RM (1999). Minisatellite mutational processes reduce F-st estimates. HUM GENET vol. 105 (6), 567-576. 01-12-1999
Saccheri IJ, Wilson IJ, Nichols RA, Bruford MW and Brakefield PM (1999). Inbreeding of bottlenecked butterfly populations: Estimation using the likelihood of changes in marker allele frequencies. GENETICS vol. 151 (3), 1053-1063. 01-03-1999
Byrne K and Nichols RA (1999). Culex pipiens in London Underground tunnels: differentiation between surface and subterranean populations. Heredity (Edinb) vol. 82 ( Pt 1), 7-15. 01-01-1999
NICHOLS RA (1999). The introduction of molecular genetic techniques into forensic science. Biotechnology, the Science & the business , Editors: RE SDMMC. 649-657. 01-01-1999
1997
Brown RJ, Malcolm CA, Mason PL and Nichols RA (1997). Genetic differentiation between and within strains of the saw-toothed grain beetle, Oryzaephilus surinamensis (Coleoptera: Silvanidae) at RAPD loci. Insect Mol Biol vol. 6 (3), 285-289. 01-08-1997
Balding DJ and Nichols RA (1997). Significant genetic correlations among Caucasians at forensic DNA loci. Heredity (Edinb) vol. 78 ( Pt 6), 583-589. 01-06-1997
Mason PL, Brown RJ and Nichols RA (1997). Population structure and insecticidal control of the sawtoothed grain beetle (Coleoptera: Silvanidae) under simulated field conditions. J ECON ENTOMOL vol. 90 (1), 27-37. 01-02-1997
1996
Beaumont MA and Nichols RA (1996). Evaluating loci for use in the genetic analysis of population structure. P ROY SOC LOND B BIO vol. 263 (1377), 1619-1626. 22-12-1996
Saccheri IJ, Brakefield PM and Nichols RA (1996). Severe inbreeding depression and rapid fitness rebound in the butterfly Bicyclus anynana (Satyridae). EVOLUTION vol. 50 (5), 2000-2013. 01-10-1996
Ibrahim KM, Nichols RA and Hewitt GM (1996). Spatial patterns of genetic variation generated by different forms of dispersal during range expansion. HEREDITY vol. 77, 282-291. 01-09-1996
NICHOLS RA (1996). Is it ancient or modern history that we can read in the genes? Aspects of the Genesis and Maintenance of Biological Diversity , Editors: Hochberg ME, Clobert J and Barbault R. 69-87. 01-01-1996
NICHOLS RA (1996). Assessing relatedness and evolutionary divergence: why the genetic evidence alone is not enough. Molecular Genetic Approaches in Conservation , Editors: RK STW. 365-382. 01-01-1996
Balding DJ, Greenhalgh M and Nichols RA (1996). Population genetics of STR loci in Caucasians. Int J Legal Med vol. 108 (6), 300-305. 01-01-1996
1995
BALDING D and NICHOLS R (1995). A METHOD FOR QUANTIFYING DIFFERENTIATION BETWEEN POPULATIONS AT MULTI-ALLELIC LOCI AND ITS IMPLICATIONS FOR INVESTIGATING IDENTITY AND PATERNITY. GENETICA, Springer Verlag vol. 96 (1-2), 3-12. 01-06-1995
MASON PL, NICHOLS RA and HEWITT GM (1995). PHILOPATRY IN THE ALPINE GRASSHOPPER, PODISMA-PEDESTRIS - A NOVEL EXPERIMENTAL AND ANALYTICAL METHOD. ECOL ENTOMOL vol. 20 (2), 137-145. 01-05-1995
Balding DJ and Nichols RA (1995). A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity. Genetica vol. 96 (1-2), 3-12. 01-01-1995
Balding DJ and Nichols RA (1995). A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity. Human Identification: The Use of DNA Markers 3-12. 01-01-1995
1994
BALDING DJ, DONNELLY P and NICHOLS RA (1994). SOME CAUSES FOR CONCERN ABOUT DNA PROFILES - COMMENT. STAT SCI vol. 9 (2), 248-251. 01-05-1994
NICHOLS RA and HEWITT GM (1994). THE GENETIC CONSEQUENCES OF LONG-DISTANCE DISPERSAL DURING COLONIZATION. HEREDITY vol. 72, 312-317. 01-03-1994
Balding DJ and Nichols RA (1994). DNA profile match probability calculation: how to allow for population stratification, relatedness, database selection and single bands. Forensic Sci Int vol. 64 (2-3), 125-140. 01-02-1994
Balding DJ, Donnelly P and Nichols RA (1994). Comment: Some causes for concern about DNA profiles. Statistical Science vol. 9 (2), 248-252. 01-01-1994
1992
Balding DJ, Nichols RA and Hunt DM (1992). Detecting gene conversion: primate visual pigment genes. Proc Biol Sci vol. 249 (1326), 275-280. 22-09-1992
NICHOLS RA and BUTLIN RK (1992). SEXUAL PREFERENCE AND GENETIC CORRELATIONS. TRENDS ECOL EVOL vol. 7 (1), 29-30. 01-01-1992
1991
Nichols RA and Balding DJ (1991). Effects of population structure on DNA fingerprint analysis in forensic science. Heredity (Edinb) vol. 66 ( Pt 2), 297-302. 01-04-1991
1989
NICHOLS RA (1989). THE FRAGMENTATION OF TENSION ZONES IN SPARSELY POPULATED AREAS. AM NAT vol. 134 (6), 969-977. 01-12-1989
NICHOLS RA (1989). MITOCHONDRIAL-DNA CLUES TO GOPHER TORTOISE DISPERSAL. TRENDS ECOL EVOL vol. 4 (7), 192-193. 01-07-1989
HEWITT GM, MASON P and NICHOLS RA (1989). SPERM PRECEDENCE AND HOMOGAMY ACROSS A HYBRID ZONE IN THE ALPINE GRASSHOPPER PODISMA-PEDESTRIS. HEREDITY vol. 62, 343-353. 01-06-1989
NICHOLS RA and BUTLIN RK (1989). DOES RUNAWAY SEXUAL SELECTION WORK IN FINITE POPULATIONS. J EVOLUTION BIOL vol. 2 (4), 299-313. 01-01-1989
1988
HEWITT GM, NICHOLS RA and RITCHIE MG (1988). ECOLOGICAL GENETICS - 1868 AND ALL THAT FOR MAGICICADA. NATURE vol. 336 (6196), 206-207. 17-11-1988
NICHOLS RA and HEWITT GM (1988). GENETIC AND ECOLOGICAL DIFFERENTIATION ACROSS A HYBRID ZONE. ECOL ENTOMOL vol. 13 (1), 39-49. 01-02-1988
1987
HEWITT GM, NICHOLS RA and BARTON NH (1987). HOMOGAMY IN A HYBRID ZONE IN THE ALPINE GRASSHOPPER PODISMA-PEDESTRIS. HEREDITY vol. 59, 457-466. 01-12-1987
1986
NICHOLS RA and HEWITT GM (1986). POPULATION-STRUCTURE AND THE SHAPE OF A CHROMOSOMAL CLINE BETWEEN 2 RACES OF PODISMA-PEDESTRIS (ORTHOPTERA, ACRIDIDAE). BIOL J LINN SOC vol. 29 (4), 301-316. 01-12-1986
DELATORRE J, LOPEZFERNANDEZ C, NICHOLS R and GOSALVEZ J (1986). HETEROCHROMATIN READJUSTING CHIASMA DISTRIBUTION IN 2 SPECIES OF THE GENUS ARCYPTERA - THE EFFECT AMONG INDIVIDUALS AND POPULATIONS. HEREDITY vol. 56, 177-184. 01-04-1986
Grants
Grants of specific relevance to the Centre for Biodiversity and SustainabilityPredicting risk to non-native trees species from potential threats in the UKRichard Nichols
£13,521 DEFRA Department for Environment, Food & Rural Affairs (DEFRA) (01-10-2023 - 31-03-2025)
PhD studentship - Assessing the risk to plant health in the UK from future Agrilus invasionsRichard Nichols
£79,125 DEFRA Department for Environment, Food & Rural Affairs (DEFRA) (01-10-2020 - 31-03-2024)
A high-throughput platform for assembling genome data: the SaphyrStephen Rossiter, Richard Nichols and Chema Martin Duran
£271,357 NERC Natural Environment Research Council (01-10-2019 - 31-03-2020)
NERC DTP CASE Award - Charlotte Ford studentship top upRichard Nichols
£4,000 CEFAS Centre for Environment Fisheries and Aquaculture Science (01-09-2019 - 31-08-2023)
GCRF Ethiopian project with KewRichard Nichols and Adrian Larkeryd
£329,633 BBSRC Biotechnology and Biological Sciences Research Council (01-04-2019 - 30-09-2021)