Prof Richard Nichols

Richard Nichols
BSc PhD FLS

Professor of Evolutionary Genetics

School of Biological and Behavioural Sciences
Queen Mary University of London
www.qmul.ac.uk/sbbs/staff/richardnichols.html
Centre for Evolutionary and Functional Genomics
Centre for Biodiversity and Sustainability
ResearcherID ORCID Scopus Google Scholar LinkedIn X

Research

Population Genetics, Evolutionary Genomics, Bayesian Analysis, Conservation, Range Expansion, Invasive Species

Interests

My work combines the collection of genetic data with the development of new analytical methods. I interpret genetic patterns to ask how populations have spread or contracted, merged or been fragmented and how they have been shaped by natural selection.

I apply this approach to a wide diversity of organisms:

Trees: I work with colleagues at Kew to counteract threats to British trees, encompassing projects to identify the genetic basis of resistance to invasive diseases of Ash trees (with Richard Buggs) and exploiting phylogenetic information to anticipate threats from invasive beetles (with Laura Kelly).

Viruses: with Trent Garner (Institute of Zoology) I study the spread of wildlife viruses affecting fish, reptiles, and amphibians. I ask why they have recently appeared in new locations & species.

Human cancer cells: I work with Trevor Graham (Barts Cancer Institute) using experiments on cancer cell lines to ask if we can identify strategies to retard resistance to chemotherapy, by exploiting evolutionary insights.

Model organisms: conducting experimental evolution, for example on Drosophila fruit flies (with Bill Sherwin in UNSW), I ask if there are flaws or omissions in our current evolutionary models.

Crops: I am a member of a project with (The Natural Resources Institute and Kew) to identify crop varieties that will be resilient to climate change in Ethiopia.

Publications

solid heart iconPublications of specific relevance to the Centre for Biodiversity and Sustainability

2024

Relevant PublicationNitrogen and phosphorus interactions at a 21 nitrogen:1 phosphorus Redfield‐like ratio impact growth and seed yield in wheat (Triticum aestivum L.)
da Silva SSM, Faizullah L, Guignard MS, Orcen N, Ruban AV, Rudall PJ, Trimmer M, Nichols RA, Leitch IJ and Leitch AR
Food and Energy Security, Wiley vol. 13 (4) 
30-07-2024

2023

Relevant PublicationMaintenance and expansion of genetic and trait variation following domestication in a clonal crop
White OW, Biswas MK, Abebe WM, Dussert Y, Kebede F, Nichols RA, Buggs RJA, Demissew S, Woldeyes F, Papadopulos AST, Schwarzacher T, Heslop‐Harrison PJS, Wilkin P and Borrell JS
Molecular Ecology, Wiley vol. 32 (15), 4165-4180.  
02-06-2023
bullet iconAssembly‐free quantification of vagrant DNA inserts
Becher H and Nichols RA
Molecular Ecology Resources, Wiley vol. 23 (5), 1002-1013.  
15-02-2023

2022

Relevant PublicationNon-Lethal Detection of Frog Virus 3-Like (RUK13) and Common Midwife Toad Virus-Like (PDE18) Ranaviruses in Two UK-Native Amphibian Species
Ford CE, Brookes LM, Skelly E, Sergeant C, Jordine T, Balloux F, Nichols RA and Garner TWJ
Viruses, Mdpi vol. 14 (12) 
25-11-2022
Relevant PublicationWhi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell
Lau Y, Oamen HP, Grogg M, Parfenova I, Saarikangas J, Hannay R, Nichols RA, Hilvert D, Barral Y and Caudron F
Current Biology, Elsevier vol. 32 (5), 963-974.e7.  
31-01-2022
Relevant PublicationCyto-nuclear incompatibilities across a bluebell hybrid zone in northern Spain do not prevent genome-wide introgression of neutral markers
Marquardt J, Blanckaert A, Nichols RA, Ansell SW, Ruhsam M, Hollingsworth PM, Metzler D, Schneider H and Leitch AR
Evolutionary Journal of The Linnean Society, Oxford University Press (Oup) vol. 1 (1), kzac003-kzac003.  
01-01-2022

2021

Relevant PublicationEvidence for the Widespread Occurrence of Bacteria Implicated in Acute Oak Decline from Incidental Genetic Sampling
Gathercole LAP, Nocchi G, Brown N, Coker TLR, Plumb WJ, Stocks JJ, Nichols RA, Denman S and Buggs RJA
Forests vol. 12 (12), 1683-1683.  
01-12-2021
Relevant PublicationSpatially clustered count data provide more efficient search strategies in invasion biology and disease control.
Stevens MCA, Faulkner SC, Wilke ABB, Beier JC, Vasquez C, Petrie W, Fry H, Nichols RA, Verity R and Le Comber SC
Ecol Appl, Ecological Society of America, e2329-e2329.  
22-03-2021

2020

bullet iconCorrection: Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants.
Martinez-Ruiz C, Pracana R, Stolle E, Paris CI, Nichols RA and Wurm Y
Elife, Elife Sciences Publications Ltd vol. 9 
09-11-2020
Relevant PublicationGenomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants
Martinez-Ruiz C, Pracana R, Stolle E, Paris CI, Nichols RA and Wurm Y
Elife, Elife vol. 9 
10-08-2020

2019

Relevant PublicationGenomic basis of European ash tree resistance to ash dieback fungus
Stocks J, Metheringham C, Plumb W, Lee S, Kelly L, Nichols R and Buggs R
Nature Ecology and Evolution, Nature Research 
18-11-2019
Relevant PublicationGenomic assessment of local adaptation in dwarf birch to inform assisted gene flow
BORRELL J, ZOHREN J, Nichols R and Buggs R
Evolutionary Applications: Evolutionary Approaches to Environmental, Biomedical and Socio-Economic Issues, Wiley 
20-10-2019
bullet iconModelling Ranavirus Transmission in Populations of Common Frogs (Rana temporaria) in the United Kingdom
Duffus ALJ, Garner TWJ, Nichols RA, Standridge JP and Earl JE
Viruses, Mdpi vol. 11 (6) 
15-06-2019
bullet iconEffects of historic and projected climate change on the range and impacts of an emerging wildlife disease
Price SJ, Leung WTM, Owen CJ, Puschendorf R, Sergeant C, Cunningham AA, Balloux F, Garner TWJ and Nichols RA
Global Change Biology, Wiley vol. 25 (8), 2648-2660.  
09-05-2019
bullet iconInteractions between plant genome size, nutrients and herbivory by rabbits, molluscs and insects on a temperate grassland
Guignard MS, Crawley MJ, Kovalenko D, Nichols RA, Trimmer M, Leitch AR and Leitch IJ
Proceedings of The Royal Society B, The Royal Society vol. 286 (1899) 
20-03-2019
bullet iconGenome-wide haplotype analysis improves trait predictions in Brassica napus hybrids
Jan HU, Guan M, Yao M, Liu W, Wei D, Abbadi A, Zheng M, He X, Chen H, Guan C, Nichols RA, Snowdon RJ, Hua W and Qian L
Plant Science vol. 283, 157-164.  
13-03-2019

2018

Relevant PublicationGenetic diversity maintained among fragmented populations of a tree undergoing range contraction.
Borrell JS, Wang N, Nichols RA and Buggs RJA
Heredity (Edinb) vol. 121 (4), 304-318.  
01-10-2018

2017

Relevant PublicationThe fire ant social chromosome supergene variant Sb shows low diversity but high divergence from SB
Pracana R, Priyam A, Levantis I, Nichols RA and Wurm Y
Molecular Ecology, Wiley vol. 26 (11), 2864-2879.  
01-04-2017
bullet iconGenetic linkage to explain genetic variation
Mijangos JL, Holleley CE, Nichols RA, Towers IN, Jovanoski Z, Sidhu HS, Watt S, Adamack AT and Sherwin WB
Proceedings - 22nd International Congress on Modelling and Simulation, MODSIM 2017., 127-133.  
01-01-2017

2016

bullet iconReconstructing the emergence of a lethal infectious disease of wildlife supports a key role for spread through translocations by humans.
Price SJ, Garner TW, Cunningham AA, Langton TE and Nichols RA
Proc Biol Sci vol. 283 (1839) 
28-09-2016
bullet iconEstimating the Number of Subpopulations (K) in Structured Populations
Verity R and Nichols RA
Genetics: a Periodical Record of Investigations Bearing On Heredity and Variation, Genetics Society of America vol. 203 (4), 1827-1839.  
01-08-2016
bullet iconDocumentation for MAVERICK software: Version 1.0
Verity R and Nichols RA
Genetics vol. 203 (4) 
01-08-2016
bullet iconFile s1: Derivation of evidence estimators and model comparison statistics
Verity R and Nichols RA
Genetics vol. 203 (4) 
01-08-2016
Relevant PublicationUnidirectional diploid-tetraploid introgression among British birch trees with shifting ranges shown by RAD markers
Zohren J, Wang N, Kardailsky I, Borrell JS, Joecker A, Nichols RA and Buggs RJA
Molecular Ecology, Wiley: 12 Months 
11-05-2016
Relevant PublicationGenome size and ploidy influence angiosperm species’ biomass under nitrogen and phosphorus limitation
Guignard MS, Nichols RA, Knell RJ, Macdonald A, Romila C-A, Trimmer M, Leitch IJ and LEITCH AR
New Phytologist, John Wiley & Sons, Inc 
15-02-2016
bullet iconGenomic Prediction of Testcross Performance in Canola (Brassica napus)
Jan HU, Abbadi A, Lücke S, Nichols RA and Snowdon RJ
Plos One, Public Library of Science (Plos) vol. 11 (1) 
29-01-2016

2015

bullet iconAnalysis of the giant genomes of Fritillaria (Liliaceae) indicates that a lack of DNA removal characterizes extreme expansions in genome size
Kelly LJ, Renny‐Byfield S, Pellicer J, Macas J, Novák P, Neumann P, Lysak MA, Day PD, Berger M, Fay MF, Nichols RA, Leitch AR and Leitch IJ
New Phytologist, Wiley vol. 208 (2), 596-607.  
08-06-2015
bullet iconRates of Vaccine Evolution Show Strong Effects of Latency: Implications for Varicella Zoster Virus Epidemiology
Weinert LA, Depledge DP, Kundu S, Gershon AA, Nichols RA, Balloux F, Welch JJ and Breuer J
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 32 (4), 1020-1028.  
06-01-2015

2014

bullet iconDetection of a frog virus 3-like ranavirus in native and introduced amphibians in the United Kingdom in 2007 and 2008
Duffus ALJ, Nichols RA and Garner TWJ
Herpetological Review vol. 45 (4), 608-610.  
01-12-2014
bullet iconExperimental evidence in support of single host maintenance of a multihost pathogen
Duffus ALJ, Nichols RA and Garner TWJ
Ecosphere, Wiley vol. 5 (11), 1-11.  
01-11-2014
bullet iconCollapse of Amphibian Communities Due to an Introduced Ranavirus
Price SJ, Garner TWJ, Nichols RA, Balloux F, Ayres C, de Alba AM-C and Bosch J
Current Biology, Elsevier vol. 24 (21), 2586-2591.  
16-10-2014
bullet iconWhat is genetic differentiation, and how should we measure it--GST, D, neither or both?
Verity R and Nichols RA
Mol Ecol vol. 23 (17), 4216-4225.  
01-09-2014
Relevant PublicationMolecular footprints of the Holocene retreat of dwarf birch in Britain.
Wang N, Borrell JS, Bodles WJA, Kuttapitiya A, Nichols RA and Buggs RJA
Mol Ecol vol. 23 (11), 2771-2782.  
01-06-2014
bullet iconInside the Melanoplinae: new molecular evidence for the evolutionary history of the Eurasian Podismini (Orthoptera: Acrididae).
Chintauan-Marquier IC, Amédégnato C, Nichols RA, Pompanon F, Grandcolas P and Desutter-Grandcolas L
Mol Phylogenet Evol vol. 71, 224-233.  
01-02-2014
bullet iconSpatial targeting of infectious disease control: Identifying multiple, unknown sources
Verity R, Stevenson MD, Rossmo DK, Nichols RA and Le Comber SC
Methods in Ecology and Evolution vol. 5 (7), 647-655.  
01-01-2014
bullet iconTesting single-sample estimators of effective population size in genetically structured populations
Holleley CE, Nichols RA, Whitehead MR, Adamack AT, Gunn MR and Sherwin WB
Conservation Genetics vol. 15 (1), 23-35.  
01-01-2014
bullet iconPurifying selection in deeply conserved human enhancers is more consistent than in coding sequences.
De Silva DR, Nichols R and Elgar G
Plos One vol. 9 (7) 
01-01-2014
bullet iconMolecular footprints of the Holocene retreat of dwarf birch in Britain
Wang N, Borrell JS, Bodles WJA, Kuttapitiya A, Nichols RA and Buggs RJA
Molecular Ecology 
01-01-2014

2013

bullet iconConservation Genetic Resources for Effective Species Survival (ConGRESS): Bridging the divide between conservation research and practice
Hoban S, Arntzen JW, Bertorelle G, Bryja J, Fernandes M, Frith K, Gaggiotti O, Galbusera P, Godoy JA, Hauffe HC, Rus Hoelzel A, Nichols RA, Pérez-Espona S, Primmer C, Russo IRM, Segelbacher G, Siegismund HR, Sihvonen M, Sjögren-Gulve P, Vernesi C, et al.
Journal For Nature Conservation vol. 21 (6), 433-437.  
01-12-2013
bullet iconInvestigations into the life history stages of the common frog (Rana temporaria) affected by an amphibian ranavirus in the United Kingdom
Duffus ALJ, Nichols RA and Garner TWJ
Herpetological Review vol. 44 (2), 260-263.  
01-12-2013
bullet iconDeep Sequencing of Viral Genomes Provides Insight into the Evolution and Pathogenesis of Varicella Zoster Virus and Its Vaccine in Humans
Depledge DP, Kundu S, Jensen NJ, Gray ER, Jones M, Steinberg S, Gershon A, Kinchington PR, Schmid DS, Balloux F, Nichols RA and Breuer J
Molecular Biology and Evolution, Oxford University Press (Oup) vol. 31 (2), 397-409.  
25-10-2013
bullet iconDiploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences.
Renny-Byfield S, Kovarik A, Kelly LJ, Macas J, Novak P, Chase MW, Nichols RA, Pancholi MR, Grandbastien M-A and Leitch AR
Plant J vol. 74 (5), 829-839.  
01-06-2013
bullet iconDiploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences
Renny-Byfield S, Kovarik A, Kelly LJ, MacAs J, Novak P, Chase MW, Nichols RA, Pancholi MR, Grandbastien MA and Leitch AR
Plant Journal vol. 74 (5), 829-839.  
01-06-2013
bullet iconGodfrey M Hewitt (1940-2013): highlights in Heredity from a career in evolutionary genetics.
Nichols RA, Butlin RK and Bruford MW
Heredity (Edinb) vol. 110 (5), 405-406.  
01-05-2013
bullet iconHybridization and speciation
Abbott R, Albach D, Ansell S, Arntzen JW, Baird SJE, Bierne N, Boughman JW, Brelsford A, Buerkle CA, Buggs R, Butlin RK, Dieckmann U, Eroukhmanoff F, Grill A, Cahan SH, Hermansen JS, Hewitt G, Hudson AG, Jiggins C, Jones J, et al.
Journal of Evolutionary Biology vol. 26 (2), 229-246.  
01-01-2013
bullet iconNext generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids
Matyasek R, Renny-Byfield S, Fulnecek J, Macas J, Grandbastien M-A, Nichols R, Leitch A and Kovarik A
Bmc Genomics, Biomed Central Ltd vol. 13 (722) 
01-01-2013
bullet iconBringing genetic diversity to the forefront of conservation policy and management
Hoban SM, Hauffe HC, Perez-Espona S, Arntzen JW, Bertorelle G, Bryja J, Frith K, Gaggiotti OE, Galbusera P, Godoy JA, Hoelzel AR, Nichols RA, Primmer CR, Russo I-R, Segelbacher G, Siegismund HR, Sihvonen M, Vernesi C, Vila C and Bruford MW
Conservation Genetics Resources vol. 5 (2), 593-598.  
01-01-2013
bullet iconConservation Genetic Resources for Effective Species Survival (ConGRESS): Bridging the divide between conservation research and practice
Hoban S, Arntzen JW, Bertorelle G, Bryja J, Fernandes M, Frith K, Gaggiotti O, Galbusera P, Godoy JA, Hauffe HC, Rus Hoelzel A, Nichols RA, Pérez-Espona S, Primmer C, Russo I-RM, Segelbacher G, Siegismund HR, Sihvonen M, Sjögren-Gulve P, Vernesi C, et al.
Journal For Nature Conservation 
01-01-2013
bullet iconSample Planning Optimization Tool for conservation and population Genetics (SPOTG): a software for choosing the appropriate number of markers and samples
Hoban S, Gaggiotti O, Bertorelle G, Arntzen P, Bryja J, Fernandes M, Frith K, Galbusera P, Godoy JA, Hauffe HC, Hoelzel R, Nichols R, Perez-Espona S, Primmer C, Russo I-RM, Segelbacher G, Siegismund HR, Sihvonen M, Sjoegren-Gulve P, Vernesi C, et al.
Methods in Ecology and Evolution vol. 4 (3), 299-303.  
01-01-2013

2012

bullet iconIndependent, rapid and targeted loss of highly repetitive DNA in natural and synthetic allopolyploids of Nicotiana tabacum.
Renny-Byfield S, Kovařík A, Chester M, Nichols RA, Macas J, Novák P and Leitch AR
Plos One vol. 7 (5) 
01-01-2012

2011

bullet iconNext generation sequencing reveals genome downsizing in allotetraploid Nicotiana tabacum, predominantly through the elimination of paternally derived repetitive DNAs.
Renny-Byfield S, Chester M, Kovařík A, Le Comber SC, Grandbastien M-A, Deloger M, Nichols RA, Macas J, Novák P, Chase MW and Leitch AR
Mol Biol Evol vol. 28 (10), 2843-2854.  
01-10-2011
bullet iconPredictions of single-nucleotide polymorphism differentiation between two populations in terms of mutual information.
Dewar RC, Sherwin WB, Thomas E, Holleley CE and Nichols RA
Mol Ecol vol. 20 (15), 3156-3166.  
01-08-2011
bullet iconStops making sense: translational trade-offs and stop codon reassignment.
Johnson LJ, Cotton JA, Lichtenstein CP, Elgar GS, Nichols RA, Polly PD and Le Comber SC
Bmc Evol Biol vol. 11 
29-07-2011
bullet iconPopulation diversity in batches of the varicella Oka vaccine
Kanda RK, Quinlivan ML, Gershon AA, Nichols RA and Breuer J
Vaccine vol. 29 (17), 3293-3298.  
12-04-2011
bullet iconHousehold size is critical to varicella-zoster virus transmission in the tropics despite lower viral infectivity.
Nichols RA, Averbeck KT, Poulsen AG, al Bassam MM, Cabral F, Aaby P and Breuer J
Epidemics vol. 3 (1), 12-18.  
01-03-2011
bullet iconInduced dispersal in wildlife management: experimental evaluation of the risk of hybrid breakdown and the benefit of hybrid vigor in the F1 generation
Holleley CE, Nichols RA, Whitehead MR, Gunn MR, Gupta J and Sherwin WB
Conserv Genet vol. 12 (1), 31-40.  
01-02-2011
bullet iconPhylogenetic relationships in Pterodroma petrels are obscured by recent secondary contact and hybridization.
Brown RM, Jordan WC, Faulkes CG, Jones CG, Bugoni L, Tatayah V, Palma RL and Nichols RA
Plos One vol. 6 (5) 
01-01-2011

2010

bullet iconRange expansion and hybridization in Round Island petrels (Pterodroma spp.): evidence from microsatellite genotypes.
Brown RM, Nichols RA, Faulkes CG, Jones CG, Bugoni L, Tatayah V, Gottelli D and Jordan WC
Mol Ecol vol. 19 (15), 3157-3170.  
01-08-2010

2009

bullet iconPopulation genetic patterns suggest a behavioural change in wild common frogs (Rana temporaria) following disease outbreaks (Ranavirus)
Teacher AGF, Garner TWJ and Nichols RA
Mol Ecol vol. 18 (15), 3163-3172.  
01-08-2009
bullet iconGeographically localised bursts of ribosomal DNA mobility in the grasshopper Podisma pedestris.
Veltsos P, Keller I and Nichols RA
Heredity (Edinb) vol. 103 (1), 54-61.  
01-07-2009
bullet iconEuropean phylogeography of the common frog (Rana temporaria): routes of postglacial colonization into the British Isles, and evidence for an Irish glacial refugium.
Teacher AGF, Garner TWJ and Nichols RA
Heredity (Edinb) vol. 102 (5), 490-496.  
01-05-2009
bullet iconEvidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus).
Teacher AGF, Garner TWJ and Nichols RA
Plos One vol. 4 (2) 
01-01-2009

2008

bullet iconThe inexorable spread of a newly arisen neo-Y chromosome.
Veltsos P, Keller I and Nichols RA
Plos Genet vol. 4 (5) 
30-05-2008
bullet iconA method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity (vol 96, pg 3, 1995)
Balding DJ and Nichols RA
Genetica vol. 133 (1), 107-107.  
01-05-2008
bullet iconThe frequency of rDNA variants within individuals provides evidence of population history and gene flow across a grasshopper hybrid zone.
Keller I, Veltsos P and Nichols RA
Evolution vol. 62 (4), 833-844.  
01-04-2008
bullet iconThe role of vicariance vs. dispersal in shaping genetic patterns in ocellated lizard species in the western Mediterranean
Paulo OS, Pinheiro J, Miraldo A, Bruford MW, Jordan WC and Nichols RA
Mol Ecol vol. 17 (6), 1535-1551.  
01-03-2008

2007

bullet iconLandscape, habitat characteristics and the genetic population structure of two caddisflies
Wilcock HR, Bruford MW, Nichols RA and Hildrew AG
Freshwater Biol vol. 52 (10), 1907-1929.  
01-10-2007
bullet iconDNA sequence variability in Oka vaccine isolates
Breuer J, Quinlivan M, Al Bassam M, Macdonald S, Nichols RA, Steinberg SP, La Russa P and Gershon AA
J Infect Dis vol. 196 (5), 801-802.  
01-09-2007
bullet iconDates from the molecular clock: how wrong can we be?
Pulquério MJF and Nichols RA
Trends Ecol Evol vol. 22 (4), 180-184.  
01-04-2007
bullet iconTransition-transversion bias is not universal: a counter example from grasshopper pseudogenes.
Keller I, Bensasson D and Nichols RA
Plos Genet vol. 3 (2) 
02-02-2007
bullet iconNatural selection for rash-forming genotypes of the varicella-zoster vaccine virus detected within immunized human hosts
Quinlivan ML, Gershon AA, Al Bassam MM, Steinberg SP, LaRussa P, Nichols RA and Breuer J
P Natl Acad Sci Usa vol. 104 (1), 208-212.  
02-01-2007

2006

bullet iconGenome-wide characterisation of Hepatitis B mutations involved in clinical outcome
Szmaragd C, Foster GR, Manica A, Bartholomeusz A, Nichols RA and Balloux F
Heredity vol. 97 (6), 389-397.  
01-12-2006
bullet iconRibosomal DNA in the grasshopper Podisma pedestris: escape from concerted evolution.
Keller I, Chintauan-Marquier IC, Veltsos P and Nichols RA
Genetics vol. 174 (2), 863-874.  
01-10-2006
bullet iconMorphological differentiation following experimental bottlenecks in the butterfly Bicyclus anynana (Nymphalidae)
Saccheri IJ, Nichols RA and Brakefield PM
Biol J Linn Soc vol. 89 (1), 107-115.  
01-09-2006
bullet iconNatural selection of rash-forming genotypes of the varicella vaccine virus within humans
Quinlivan ML, Gershon AA, Albassam MM, Steinberg SP, IaRussa P, Sharrar RA, Nichols RA and Breuer J
JOURNAL OF CLINICAL VIROLOGY. vol. 36, S23-S23.  
01-08-2006
bullet iconVaccine Oka varicella-zoster virus genotypes are monomorphic in single vesicles and polymorphic in respiratory tract secretions
Quinlivan MA, Gershon AA, Nichols RA, La Russa P, Steinberg SP and Breuer J
J Infect Dis vol. 193 (7), 927-930.  
01-04-2006
bullet iconA novel approach to characterise pathogen candidate genetic polymorphisms involved in clinical outcome
Szmaragd C, Nichols RA and Balloux F
Infect Genet Evol vol. 6 (1), 38-45.  
01-01-2006
bullet iconHepatitis B virus mutations involved in clinical outcome
Szmaragd C, Foster GR, Manica A, Bartholomeusz A, Nichols RA and Balloux F
Journal of Hepatology vol. 44, 400-400.  
01-01-2006

2005

bullet iconRecruitment, kin and the spatial genetic structure of a caddisfly Plectrocnemia conspersa in a southern English stream
Wilcock HR, Bruford MW, Hildrew AG and Nichols RA
Freshwater Biol vol. 50 (9), 1499-1514.  
01-09-2005
bullet iconQuantitative genetics focus issue
Nichols RA
Heredity, Springer Nature vol. 94 (3), 273-274.  
24-02-2005
bullet iconGenetic and Evolutionary Impacts of Climate Change
Hewitt GM and NICHOLS RA
In Climate Change and Biodiversity, Yale University Press 176-192. Editors: Lovejoy TE and Hannah L. 
01-01-2005

2004

bullet iconThe origin and evolution of geminivirus-related DNA sequences in Nicotiana.
Murad L, Bielawski JP, Matyasek R, Kovarík A, Nichols RA, Leitch AR and Lichtenstein CP
Heredity (Edinb) vol. 92 (4), 352-358.  
01-04-2004
bullet iconMolecular phylogeny and morphological change in the Psittacula parakeets.
Groombridge JJ, Jones CG, Nichols RA, Carlton M and Bruford MW
Mol Phylogenet Evol vol. 31 (1), 96-108.  
01-04-2004
bullet iconUsing molecular markers with high mutation rates to obtain estimates of relative population size and to distinguish the effects of gene flow and mutation: a demonstration using data from endemic Mauritian skinks.
Nichols RA and Freeman KLM
Mol Ecol vol. 13 (4), 775-787.  
01-04-2004

2003

bullet iconAn analysis of consanguinity and social structure within the UK Asian population using microsatellite data.
Overall ADJ, Ahmad M, Thomas MG and Nichols RA
Ann Hum Genet vol. 67 (Pt 6), 525-537.  
01-11-2003
bullet iconGenetic population structure and neighbourhood population size estimates of the caddisfly Plectrocnemia conspersa
Wilcock HR, Nichols RA and Hildrew AG
Freshwater Biol vol. 48 (10), 1813-1824.  
01-10-2003
bullet iconApplication of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis.
Hinchliffe SJ, Isherwood KE, Stabler RA, Prentice MB, Rakin A, Nichols RA, Oyston PCF, Hinds J, Titball RW and Wren BW
Genome Res vol. 13 (9), 2018-2029.  
01-09-2003

2002

bullet iconA molecular phylogeny of African kestrels with reference to divergence across the Indian Ocean
Groombridge JJ, Jones CG, Bayes MK, van Zyl AJ, Carrillo J, Nichols RA and Bruford MW
Mol Phylogenet Evol vol. 25 (2), 267-277.  
01-11-2002
bullet iconY genetic data support the Neolithic demic diffusion model
Chikhi L, Nichols RA, Barbujani G and Beaumont MA
P Natl Acad Sci Usa vol. 99 (17), 11008-11013.  
20-08-2002
bullet iconThe effect of reproductive compensation on recessive disorders within consanguineous human populations.
Overall ADJ, Ahmad M and Nichols RA
Heredity (Edinb) vol. 88 (6), 474-479.  
01-06-2002
bullet iconUsing nested clade analysis to assess the history of colonization and the persistence of populations of an Iberian Lizard
Paulo OS, Jordan WC, Bruford MW and Nichols RA
Mol Ecol vol. 11 (4), 809-819.  
01-04-2002
bullet iconPatterns of colonization in a metapopulation of grey seals
Gaggiotti OE, Jones F, Lee WM, Amos W, Harwood J and Nichols RA
Nature vol. 416 (6879), 424-427.  
28-03-2002
bullet iconPhylogenetic analysis of varicella-zoster virus: Evidence of intercontinental spread of genotypes and recombination
Muir WB, Nichols R and Breuer J
J Virol vol. 76 (4), 1971-1979.  
01-02-2002
bullet iconA molecular phylogeny of African kestrels with reference to divergence across the Indian Ocean
Groombridge JJ, Jones CG, Bayes MK, van Zyl AJ, Carrillo J, Nichols RA and Bruford MW
Molecular Phylogenetics and Evolution, Elsevier/Science Direct vol. 25, 267-277.  
01-01-2002
bullet iconThe double origin of Iberian peninsular chameleons
Paulo OS, Pinto I, Bruford MW, Jordan WC and Nichols RA
Biol J Linn Soc vol. 75 (1), 1-7.  
01-01-2002

2001

bullet iconCulex pipiens in London Underground tunnels: differentiation between surface and subterranean populations
Byrne K and Nichols RA
Heredity vol. 82 (1), 7-15.  
25-12-2001
bullet iconMicrosatellites for the net-spinning caddisfly Plectrocnemia conspersa (Polycentropodidae)
Wilcock HR, Hildrew AG, Nichols RA and Bruford MW
Mol Ecol Notes vol. 1 (4), 318-319.  
01-12-2001
bullet iconA method for distinguishing consanguinity and population substructure using multilocus genotype data
Overall ADJ and Nichols RA
Mol Biol Evol vol. 18 (11), 2048-2056.  
01-11-2001
bullet iconThe persistence of Pliocene populations through the Pleistocene climatic cycles: evidence from the phylogeography of an Iberian lizard
Paulo OS, Dias C, Bruford MW, Jordan WC and Nichols RA
P Roy Soc Lond B Bio vol. 268 (1476), 1625-1630.  
07-08-2001
bullet iconGene trees and species trees are not the same.
Nichols R
Trends Ecol Evol vol. 16 (7), 358-364.  
01-07-2001
bullet iconGenetic differentiation of a European caddisfly: past and present gene flow among fragmented larval habitats.
Wilcock HR, Hildrew AG and Nichols RA
Mol Ecol vol. 10 (7), 1821-1834.  
01-07-2001
bullet iconMating patterns, relatedness and the basis of natal philopatry in the brown long-eared bat, Plecotus auritus
Burland TM, Barratt EM, Nichols RA and Racey PA
Mol Ecol vol. 10 (5), 1309-1321.  
01-05-2001
bullet iconEvaluating the severity of the population bottleneck in the Mauritius kestrel Falco punctatus from ringing records using MCMC estimation
Groombridge JJ, Bruford MW, Jones CG and Nichols RA
J Anim Ecol vol. 70 (3), 401-409.  
01-05-2001
bullet iconEffects of bottlenecks on quantitative genetic variation in the butterfly Bicyclus anynana
Saccheri IJ, Nichols RA and Brakefield PM
Genet Res vol. 77 (2), 167-181.  
01-04-2001
bullet iconSustaining genetic variation in a small population: evidence from the Mauritius kestrel
Nichols RA, Bruford MW and Groombridge JJ
Molecular Ecology vol. 10 (3), 593-602.  
01-03-2001

2000

bullet icon‘Ghost’ alleles of the Mauritius kestrel
Groombridge JJ, Jones CG, Bruford MW and Nichols RA
Nature, Springer Nature vol. 403 (6770), 616-616.  
01-02-2000

1999

bullet iconMinisatellite mutational processes reduce F-st estimates
Flint J, Bond J, Rees DC, Boyce AJ, Roberts-Thomson JM, Excoffier L, Clegg JB, Beaumont MA, Nichols RA and Harding RM
Hum Genet vol. 105 (6), 567-576.  
01-12-1999
bullet iconInbreeding of bottlenecked butterfly populations: Estimation using the likelihood of changes in marker allele frequencies
Saccheri IJ, Wilson IJ, Nichols RA, Bruford MW and Brakefield PM
Genetics vol. 151 (3), 1053-1063.  
01-03-1999
bullet iconCulex pipiens in London Underground tunnels: differentiation between surface and subterranean populations.
Byrne K and Nichols RA
Heredity (Edinb) vol. 82 ( Pt 1), 7-15.  
01-01-1999
bullet iconThe introduction of molecular genetic techniques into forensic science
NICHOLS RA
In Biotechnology, The Science & The Business, Harwood Academic Publishers 649-657. Editors: RE SDMMC. 
01-01-1999

1997

bullet iconGenetic differentiation between and within strains of the saw-toothed grain beetle, Oryzaephilus surinamensis (Coleoptera: Silvanidae) at RAPD loci.
Brown RJ, Malcolm CA, Mason PL and Nichols RA
Insect Mol Biol vol. 6 (3), 285-289.  
01-08-1997
bullet iconSignificant genetic correlations among Caucasians at forensic DNA loci.
Balding DJ and Nichols RA
Heredity (Edinb) vol. 78 ( Pt 6), 583-589.  
01-06-1997
bullet iconPopulation structure and insecticidal control of the sawtoothed grain beetle (Coleoptera: Silvanidae) under simulated field conditions
Mason PL, Brown RJ and Nichols RA
J Econ Entomol vol. 90 (1), 27-37.  
01-02-1997

1996

bullet iconEvaluating loci for use in the genetic analysis of population structure
Beaumont MA and Nichols RA
P Roy Soc Lond B Bio vol. 263 (1377), 1619-1626.  
22-12-1996
bullet iconSevere inbreeding depression and rapid fitness rebound in the butterfly Bicyclus anynana (Satyridae)
Saccheri IJ, Brakefield PM and Nichols RA
Evolution vol. 50 (5), 2000-2013.  
01-10-1996
bullet iconSpatial patterns of genetic variation generated by different forms of dispersal during range expansion
Ibrahim KM, Nichols RA and Hewitt GM
Heredity vol. 77, 282-291.  
01-09-1996
bullet iconIs it ancient or modern history that we can read in the genes?
NICHOLS RA
In Aspects of The Genesis and Maintenance of Biological Diversity, Oxford University Press 69-87. Editors: Hochberg ME, Clobert J and Barbault R. 
01-01-1996
bullet iconAssessing relatedness and evolutionary divergence: why the genetic evidence alone is not enough.
NICHOLS RA
In Molecular Genetic Approaches in Conservation, Oxford University Press 365-382. Editors: RK STW. 
01-01-1996
bullet iconPopulation genetics of STR loci in Caucasians.
Balding DJ, Greenhalgh M and Nichols RA
Int J Legal Med vol. 108 (6), 300-305.  
01-01-1996

1995

bullet iconA METHOD FOR QUANTIFYING DIFFERENTIATION BETWEEN POPULATIONS AT MULTI-ALLELIC LOCI AND ITS IMPLICATIONS FOR INVESTIGATING IDENTITY AND PATERNITY
BALDING D and NICHOLS R
Genetica, Springer Verlag vol. 96 (1-2), 3-12.  
01-06-1995
bullet iconPHILOPATRY IN THE ALPINE GRASSHOPPER, PODISMA-PEDESTRIS - A NOVEL EXPERIMENTAL AND ANALYTICAL METHOD
MASON PL, NICHOLS RA and HEWITT GM
Ecol Entomol vol. 20 (2), 137-145.  
01-05-1995
bullet iconA method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity.
Balding DJ and Nichols RA
Genetica vol. 96 (1-2), 3-12.  
01-01-1995
bullet iconA method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity
Balding DJ and Nichols RA
In Human Identification: The Use of Dna Markers, Springer Nature 3-12.  
01-01-1995

1994

bullet iconSOME CAUSES FOR CONCERN ABOUT DNA PROFILES - COMMENT
BALDING DJ, DONNELLY P and NICHOLS RA
Stat Sci vol. 9 (2), 248-251.  
01-05-1994
bullet iconTHE GENETIC CONSEQUENCES OF LONG-DISTANCE DISPERSAL DURING COLONIZATION
NICHOLS RA and HEWITT GM
Heredity vol. 72, 312-317.  
01-03-1994
bullet iconDNA profile match probability calculation: how to allow for population stratification, relatedness, database selection and single bands.
Balding DJ and Nichols RA
Forensic Sci Int vol. 64 (2-3), 125-140.  
01-02-1994
bullet iconComment: Some causes for concern about DNA profiles
Balding DJ, Donnelly P and Nichols RA
Statistical Science vol. 9 (2), 248-252.  
01-01-1994

1992

bullet iconDetecting gene conversion: primate visual pigment genes.
Balding DJ, Nichols RA and Hunt DM
Proc Biol Sci vol. 249 (1326), 275-280.  
22-09-1992
bullet iconSEXUAL PREFERENCE AND GENETIC CORRELATIONS
NICHOLS RA and BUTLIN RK
Trends Ecol Evol vol. 7 (1), 29-30.  
01-01-1992

1991

bullet iconEffects of population structure on DNA fingerprint analysis in forensic science.
Nichols RA and Balding DJ
Heredity (Edinb) vol. 66 ( Pt 2), 297-302.  
01-04-1991

1989

bullet iconTHE FRAGMENTATION OF TENSION ZONES IN SPARSELY POPULATED AREAS
NICHOLS RA
Am Nat vol. 134 (6), 969-977.  
01-12-1989
bullet iconMITOCHONDRIAL-DNA CLUES TO GOPHER TORTOISE DISPERSAL
NICHOLS RA
Trends Ecol Evol vol. 4 (7), 192-193.  
01-07-1989
bullet iconSPERM PRECEDENCE AND HOMOGAMY ACROSS A HYBRID ZONE IN THE ALPINE GRASSHOPPER PODISMA-PEDESTRIS
HEWITT GM, MASON P and NICHOLS RA
Heredity vol. 62, 343-353.  
01-06-1989
bullet iconDOES RUNAWAY SEXUAL SELECTION WORK IN FINITE POPULATIONS
NICHOLS RA and BUTLIN RK
J Evolution Biol vol. 2 (4), 299-313.  
01-01-1989

1988

bullet iconECOLOGICAL GENETICS - 1868 AND ALL THAT FOR MAGICICADA
HEWITT GM, NICHOLS RA and RITCHIE MG
Nature vol. 336 (6196), 206-207.  
17-11-1988
bullet iconEVOLUTION AT A SNAILS PACE
NICHOLS RA
Trends Ecol Evol vol. 3 (5), 94-95.  
01-05-1988
bullet iconGENETIC AND ECOLOGICAL DIFFERENTIATION ACROSS A HYBRID ZONE
NICHOLS RA and HEWITT GM
Ecol Entomol vol. 13 (1), 39-49.  
01-02-1988

1987

bullet iconHOMOGAMY IN A HYBRID ZONE IN THE ALPINE GRASSHOPPER PODISMA-PEDESTRIS
HEWITT GM, NICHOLS RA and BARTON NH
Heredity vol. 59, 457-466.  
01-12-1987

1986

bullet iconPOPULATION-STRUCTURE AND THE SHAPE OF A CHROMOSOMAL CLINE BETWEEN 2 RACES OF PODISMA-PEDESTRIS (ORTHOPTERA, ACRIDIDAE)
NICHOLS RA and HEWITT GM
Biol J Linn Soc vol. 29 (4), 301-316.  
01-12-1986
bullet iconHETEROCHROMATIN READJUSTING CHIASMA DISTRIBUTION IN 2 SPECIES OF THE GENUS ARCYPTERA - THE EFFECT AMONG INDIVIDUALS AND POPULATIONS
DELATORRE J, LOPEZFERNANDEZ C, NICHOLS R and GOSALVEZ J
Heredity vol. 56, 177-184.  
01-04-1986

Grants

solid heart iconGrants of specific relevance to the Centre for Biodiversity and Sustainability
solid heart iconPredicting risk to non-native trees species from potential threats in the UK
Richard Nichols
£13,521 DEFRA Department for Environment, Food & Rural Affairs (DEFRA)
01-10-2023 - 31-03-2025

solid heart iconPhD studentship - Assessing the risk to plant health in the UK from future Agrilus invasions
Richard Nichols
£79,125 DEFRA Department for Environment, Food & Rural Affairs (DEFRA)
01-10-2020 - 31-03-2024
solid heart iconA high-throughput platform for assembling genome data: the Saphyr
Stephen Rossiter, Richard Nichols and Chema Martin Duran
£271,357 NERC Natural Environment Research Council
01-10-2019 - 31-03-2020
bullet iconNERC DTP CASE Award - Charlotte Ford studentship top up
Richard Nichols
£4,000 CEFAS Centre for Environment Fisheries and Aquaculture Science
01-09-2019 - 31-08-2023
solid heart iconGCRF Ethiopian project with Kew
Richard Nichols and Adrian Larkeryd
£329,633 BBSRC Biotechnology and Biological Sciences Research Council
01-04-2019 - 30-09-2021