Dr Tina Chowdhury

BSc, MSc, PhD, PGCAP, SFHEA

Reader in Regenerative Medicine
EDI & Athena Swan Lead, Intercalated Programme Director

School of Engineering and Materials Science
Queen Mary University of London

t.t.chowdhury@qmul.ac.uk

www.sems.qmul.ac.uk/staff/t.t.chowdhury/

Centre for Bioengineering

Research
Publications
Grants

Research

Regenerative medicine, Mechanobiology, Biomechanics

Interests

We are developing novel therapeutics to slow down inflammation and repair damage to human tissues with the vision of restoring normal function. We use multi-disciplinary tools involving engineering, materials and biology to investigate the effects of stress eg. cytokines, heat, environment on inflammatory signalling pathways. Human tissues include placenta, membranes, cartilage and disc. Our research efforts are focused on translational investigation with the aim of delivering novel therapeutics that restore a healthy ageing phenotype. For example, Tina Chowdhury is Chief Investigator for a clinical trial (NCT06340971) investigating how the environment affects pregnancy outcomes and preterm birth (REC 24/EE/0047) in collaboration with the clinical teams at UCLH NHS Trust (Anna David) and Barts Health NHS Trust (Stamatina Iliodromiti).

Publications

Publications of specific relevance to the Centre for Bioengineering

2024

Role of Myofibroblasts in the Repair of Iatrogenic Preterm Membranes Subjected to Mechanical Stimulation
Costa E, Thrasivoulou C, Becker DL, Deprest J, David AL and Chowdhury TT
Prenatal Diagnosis, Wiley

DOI 10.1002/pd.6722

QMRO

04-12-2024

2023

Cx43 regulates mechanotransduction mechanisms in human preterm amniotic membrane defects
Costa E, Thrasivoulou C, Becker DL, Deprest JA, David AL and Chowdhury TT
Prenatal Diagnosis, Wiley

DOI 10.1002/pd.6429

QMRO

30-08-2023

Machine learning and disease prediction in obstetrics
Arain Z, Iliodromiti S, Slabaugh G, David AL and Chowdhury TT
Current Research in Physiology, Elsevier vol. 6

DOI 10.1016/j.crphys.2023.100099

QMRO

01-01-2023

2021

Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma
Costa E, Okesola BO, Thrasivoulou C, Becker DL, Deprest JA, David AL and Chowdhury TT
Scientific Reports, Springer Nature vol. 11 (1)

DOI 10.1038/s41598-021-94767-4

QMRO

18-08-2021

The Mechanical Interplay Between Differentiating Mesenchymal Stem Cells and Gelatin-Based Substrates Measured by Atomic Force Microscopy
Meng H, Chowdhury TT and Gavara N
Frontiers in Cell and Developmental Biology, Frontiers vol. 9

DOI 10.3389/fcell.2021.697525

QMRO

21-06-2021

2020

Potential sealing and repair of human FM defects after trauma with peptide amphiphiles and Cx43 antisense
Barrett DW, Okesola BO, Costa E, Thrasivoulou C, Becker DL, Mata A, Deprest JA, David AL and Chowdhury TT
Prenatal Diagnosis, Wiley vol. 41 (1), 89-99.

DOI 10.1002/pd.5826

QMRO

12-10-2020

Multicomponent hydrogels for the formation of vascularized bone-like constructs in vitro
Derkus B, Okesola BO, BARRETT DW, D’Este M, Chowdhury TT, Eglin D and Mata A
Acta Biomaterialia, Elsevier

DOI 10.1016/j.actbio.2020.03.025

QMRO

01-06-2020

Microwave Frequency Dependent Dielectric Properties of Blood as a Potential Technique to Measure Hydration
Dawsmith W, Ohtani N, Donnan R, Naftaly M, Dudley RA and Chowdhury TT
Ieee Access, Institute of Electrical and Electronics Engineers (Ieee), 1-1.

DOI 10.1109/access.2020.2977432

QMRO

02-03-2020

Magnetically responsive layer-by-layer microcapsules can be retained in cells and under flow conditions to promote local drug release without triggering ROS production
Read JE, Luo D, Chowdhury TT, Flower RJ, Poston RN, Sukhorukov GB and Gould DJ
Nanoscale, Royal Society of Chemistry (Rsc) vol. 12 (14), 7735-7748.

DOI 10.1039/c9nr10329e

QMRO

01-01-2020

2019

Strategies to Repair Defects in the Fetal Membrane
Chowdhury TT, Barrett DW and David AL
In Fetal Therapy, Cambridge University Press (Cup) 520-531.

DOI 10.1017/9781108564434.051

21-10-2019

Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane
BARRETT DW, John RK, Thrasivoulou C, MATA A, Deprest JA, Becker DL, David AL and CHOWDHURY TINA
Scientific Reports, Nature Publishing Group

DOI 10.1038/s41598-019-42379-4

QMRO

30-04-2019

2018

Corrigendum for Engels, Joyeux, Van der Merwe, et al. (2017) DOI: 10.1002/pd.5191
Engels AC, Joyeux L, Van der Merwe J, Jimenez J, Pranpanus S, Barrett DW, Connon C, Chowdhury TT, David AL and Deprest J
Prenatal Diagnosis, Wiley vol. 38 (6), 471-471.

DOI 10.1002/pd.5254

01-05-2018

2017

Tissuepatch is biocompatible and seals iatrogenic membrane defects in a rabbit model.
Engels AC, Joyeux L, Van der Merwe J, Jimenez J, Prapanus S, Barrett DW, Connon C, Chowdhury TT, David AL and Deprest J
Prenatal Diagnosis, Wiley vol. 38 (2), 99-105.

DOI 10.1002/pd.5191

QMRO

25-11-2017

Trauma induces overexpression of Cx43 in human fetal membrane defects
Barrett DW, Kethees A, Thrasivoulou C, Mata A, Virasami A, Sebire NJ, Engels AC, Deprest JA, Becker DL, David AL and Chowdhury TT
Prenatal Diagnosis vol. 37 (9), 899-906.

DOI 10.1002/pd.5104

QMRO

01-09-2017

2016

Connexin 43 is overexpressed in human fetal membrane defects after fetoscopic surgery
Barrett DW, David AL, Thrasivoulou C, Mata A, Becker DL, Engels AC, Deprest JA and Chowdhury TT
Prenatal Diagnosis vol. 36 (10), 942-952.

DOI 10.1002/pd.4917

QMRO

01-10-2016

Oxygen tension modulates the effects of TNFα in compressed chondrocytes.
Tilwani RK, Vessillier S, Pingguan-Murphy B, Lee DA, Bader DL and Chowdhury TT
Inflamm Res

DOI 10.1007/s00011-016-0991-5

QMRO

22-09-2016

Vergleich von konventionellem Kollagen vs. modifiziertem Kollagen zum Verschluss eines iatrogenen Blasensprungs im Kaninchen-Modell
Engels A, Joyeux L, Connon C, Chowdhury T, David A and Deprest J
Geburtshilfe und Frauenheilkunde. vol. 76 (05)

DOI 10.1055/s-0036-1583771

19-05-2016

2015

Imaging modalities for the in vivo surveillance of mesenchymal stromal cells.
Hossain MA, Chowdhury T and Bagul A
J Tissue Eng Regen Med vol. 9 (11), 1217-1224.

DOI 10.1002/term.1907

01-11-2015

C-type natriuretic peptide signalling drives homeostatic effects in human chondrocytes
Peake NJ, Bader DL, Vessillier S, Ramachandran M, Salter DM, Hobbs AJ and Chowdhury TT
Biochemical and Biophysical Research Communications, Elsevier vol. 465 (4), 784-789.

DOI 10.1016/j.bbrc.2015.08.087

22-08-2015

Polyelectrolyte microencapsules loaded with C-type natriuretic peptide protect cartilage from IL-1B induced damage
Peake N, Pavlov A, D'Souza A, Alfasahin I, Pingaan-Murphy B, Sukhurukov G, Hobbs A and Chowdhury T
Osteoarthritis and Cartilage, Elsevier vol. 23, a141-a142.

DOI 10.1016/j.joca.2015.02.881

01-04-2015

Controlled Release of C-Type Natriuretic Peptide by Microencapsulation Dampens Proinflammatory Effects Induced by IL-1β in Cartilage Explants.
Peake NJ, Pavlov AM, D'Souza A, Pingguan-Murphy B, Sukhorukov GB, Hobbs AJ and CHOWDHURY TT
Biomacromolecules, American Chemical Society

DOI 10.1021/bm501575w

QMRO

04-01-2015

2014

Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane
Chowdhury B, David AL, Thrasivoulou C, Becker DL, Bader DL and Chowdhury TT
Placenta, Elsevier vol. 35 (12), 1057-1064.

DOI 10.1016/j.placenta.2014.09.006

19-09-2014

Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function
Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and Chowdhury TT
Osteoarthritis and Cartilage, Elsevier vol. 22 (11), 1800-1807.

DOI 10.1016/j.joca.2014.07.018

31-07-2014

Role of C-type natriuretic peptide signaling in maintaining cartilage and bone function.
Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F and CHOWDHURY TT
Osteoarthritis and Cartilage, Elsevier/Science Direct vol. online edition

DOI 10.1016/j.joca.2014.07.018

30-07-2014

Imaging modalities for the in vivo surveillance of mesenchymal stromal cells
Hossain MA, CHOWDHURY TT and Bagul A
Journal of Tissue Engineering and Regenerative Medicine, Wiley

DOI 10.1002/term.1907

11-06-2014

PFM.37 Cyclic tensile strain increases PGE2 release leading to weakening of the human term amniotic membrane
Chowdhury B, David A, Bader D, Thrasivoulou C, Becker D and Chowdhury T
Archives of Disease in Childhood Fetal & Neonatal, Bmj vol. 99 (Suppl 1)

DOI 10.1136/archdischild-2014-306576.267

01-06-2014

α5β1 integrin mediates compression-induced inhibition of catabolic effects induced by fibronectin fragments in an oxygen-dependent manner
Parker E, Vessillier S, Abas WW, Bader DL, Pinguaan-Murphy B and Chowdhury TT
Osteoarthritis and Cartilage, Elsevier vol. 22

DOI 10.1016/j.joca.2014.02.572

01-04-2014

2013

Low oxygen tension increased FN-f induced catabolic activities - response prevented with biomechanical signals
Parker E, Vessillier S, Pinguaan-Murphy B, Wan Abas WAB, Bader DL and Chowdhury TT
Arthritis Research and Therapy, Biomed Central vol. 15 (5), R163-R163.

DOI 10.1186/ar4346

QMRO

25-10-2013

Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model
Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ, Hobbs AJ and Chowdhury TT
Arthritis Research and Therapy vol. 15 (4)

DOI 10.1186/ar4253

QMRO

24-07-2013

Optimisation of quantitative real-time PCR studies in cartilage mechanobiology
Akanji O, Salter DM and Chowdhury TT
In Pcr Technology. Current Innovations, Crc Pressi Llc 271-281. Editors: Nolan T and Bustin SA.

DOI 10.1201/b14930-25

03-06-2013

FN-f induced catabolic activities are dependent on oxygen tension in chondrocyte/agarose constructs subjected to biomechanical signals
Parker E, Pinguuan-Murphy B, Bader DL and Chowdhury TT
Osteoarthritis and Cartilage, Elsevier vol. 21

DOI 10.1016/j.joca.2013.02.440

01-04-2013

Biological vascular grafts for hemodialysis access.
Hossain MA, Frampton AE, Chowdhury TT and Morsey M
Expert Rev Med Devices, Informa Healthcare vol. 2 (10), 171-175.

DOI 10.1586/erd.12.85

01-03-2013

Optimization of Quantitative Real-Time PCR for Studies in Cartilage Mechanobiology
Akanji O, Salter D and Chowdhury T
In Pcr Technology: Current Innovations, Third Edition 271-281.

DOI 10.1201/b14930-23

01-01-2013

2012

Biomechanical conditioning enhanced matrix synthesis in nucleus pulposus cells cultured in agarase constructs with TGFβ
CHOWDHURY TT, Tilwani RK and Bader DL
Journal Functional Biomaterials vol. 3, 23-26. Editors: Goldsmith EC and Lin SK.

DOI 10.3390/jfb3010023

QMRO

05-01-2012

MECHANICAL SIGNALS MODULATE THE C-TYPE NATRIURETIC PEPTIDE RECEPTORS VIA CGMP AND PKG DEPENDENT PATHWAYS
Peake N, Ramachandran M, Achan P, Salter DM, Bader DL and Chowdhury TT
OSTEOARTHRITIS AND CARTILAGE. vol. 20, S243-S243.

DOI 10.1016/j.joca.2012.02.402

01-01-2012

2011

Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1β in chondrocyte/agarose constructs
Ramachandran M, Achan P, Salter DM, Bader DL and Chowdhury TT
Arthritis Research and Therapy vol. 13 (5)

DOI 10.1186/ar3459

QMRO

13-09-2011

Biomechanical influence of cartilage homeostasis in health and disease.
Bader DL, Salter DM and Chowdhury TT
Arthritis vol. 2011

DOI 10.1155/2011/979032

QMRO

01-01-2011

Quantification of mRNA using real-time PCR and Western blot analysis of MAPK events in chondrocyte/agarose constructs.
Lee DA, Brand J, Salter D, Akanji O-O and Chowdhury TT
Methods Mol Biol vol. 695, 77-97.

DOI 10.1007/978-1-60761-984-0_6

01-01-2011

2010

BIOMECHANICAL MODULATION OF COLLAGEN FRAGMENT INDUCED ANABOLIC AND CATABOLIC ACTIVITIES IN CHONDROCYTE/AGAROSE CONSTRUCTS
Chowdhury TT, Schulz RM, Rai SS, Thuemmler C, Wuestneck N, Bader A and Homandberg GA
OSTEOARTHRITIS AND CARTILAGE. vol. 18, S216-S216.

DOI 10.1016/s1063-4584(10)60507-9

01-10-2010

Biomechanical modulation of collagen fragment-induced anabolic and catabolic activities in chondrocyte/agarose constructs
Chowdhury TT, Schulz RM, Rai SS, Thuemmler CB, Wuestneck N, Bader A and Homandberg GA
Arthritis Research and Therapy vol. 12 (3)

DOI 10.1186/ar3009

QMRO

12-05-2010

Mechanical loading modulates chondrocyte primary cilia incidence and length
McGlashan SR, Knight MM, Chowdhury TT, Joshi P, Jensen CG, Kennedy S and Poole CA
Cell Biology International vol. 34 (5), 441-446.

DOI 10.1042/CBI20090094

01-01-2010

Dynamic compression alters NFκB activation and IκB-α expression in IL-1β-stimulated chondrocyte/agarose constructs
Akanji OO, Sakthithasan P, Salter DM and Chowdhury TT
Inflammation Research vol. 59 (1), 41-52.

DOI 10.1007/s00011-009-0068-9

01-01-2010

2009

Quantification of glucose and cytosine hydrochloride by THz-TDS
Shala K, Yang B, Dudley R, Chowdhury TT and Donnan RS
Loughborough Antennas and Propagation Conference, LAPC 2009 - Conference Proceedings., 501-503.

DOI 10.1109/LAPC.2009.5352455

08-12-2009

458 DYNAMIC COMPRESSION ALTERS NF?B ACTIVATION AND I?B-α EXPRESSION IN IL-1β STIMULATED CHONDROCYTE/AGAROSE CONSTRUCTS
Akanji OO, Salter DM and Chowdhury TT
Osteoarthritis and Cartilage, Elsevier vol. 17, s245-s246.

DOI 10.1016/s1063-4584(09)60479-9

01-09-2009

Dynamic compression inhibits fibronectin fragment induced iNOS and COX-2 expression in chondrocyte/agarose constructs
Raveenthiran SP and Chowdhury TT
Biomechanics and Modeling in Mechanobiology vol. 8 (4), 273-283.

DOI 10.1007/s10237-008-0134-1

01-01-2009

2008

451 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN-FRAGMENT INDUCED INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS
Raveenthiran SP and Chowdhury TT
Osteoarthritis and Cartilage, Elsevier vol. 16, s195-s196.

DOI 10.1016/s1063-4584(08)60492-6

01-09-2008

Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression
Chowdhury TT, Salter DM, Bader DL and Lee DA
Inflamm Res vol. 57 (7), 306-313.

DOI 10.1007/s00011-007-7126-y

01-07-2008

Dynamic compression influences IL-1β induced NO and PGE2 release, via alterations in iNOS and COX-2 activity
CHOWDHURY TT, Akanjii OO, Salter DM and Lee DA
In 5th International Symposium On Mechanobiology of Cartilage and Chondrocyte 689-754. Editors: Stoltz JF.
01-01-2008

Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs.
Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM and Lee DA
Arthritis Res Ther vol. 10 (2)

DOI 10.1186/ar2389

QMRO

01-01-2008

Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression
Chowdhury TT, Akanji OO, Salter DM, Bader DL and Lee DA
Biorheology vol. 45 (3-4), 257-274.

DOI 10.3233/BIR-2008-0474

01-01-2008

2007

52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION
Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL and Lee DA
Osteoarthritis and Cartilage, Elsevier vol. 15, c42-c43.

DOI 10.1016/s1063-4584(07)61688-4

01-12-2007

Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes
Campbell JJ, Blain EJ, Chowdhury TT and Knight MM
Biochemical and Biophysical Research Communications vol. 361 (2), 329-334.

DOI 10.1016/j.bbrc.2007.06.185

21-09-2007

Dynamic compression counteracts IL-1 beta b induced iNOS and COX-2 expression in chondrocytes cultured in agarose constructs
Chowdhury TT, Akanji OO, Arghandawi , Salter DM, Bader DL and Lee DA
TISSUE ENGINEERING. vol. 13 (7), 1677-1677.
01-07-2007

2006

Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression
Chowdhury TT and Knight MM
Journal of Cellular Physiology vol. 209 (3), 845-853.

DOI 10.1002/jcp.20768

01-12-2006

Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes.
Chowdhury TT, Appleby RN, Salter DM, Bader DA and Lee DA
Biomech Model Mechanobiol vol. 5 (2-3), 192-201.

DOI 10.1007/s10237-006-0032-3

01-06-2006

Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes.
Chowdhury TT, Bader DL and Lee DA
Biochem Biophys Res Commun vol. 339 (1), 241-247.

DOI 10.1016/j.bbrc.2005.11.016

06-01-2006

Dynamic compression counteracts IL-1β induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs
CHOWDHURY TT, Bader DL and Lee DA
In Mechanobiology: Cartilage and Chondrocyte, Ios Press 413-429. Editors: Stoltz JF.
01-01-2006

Mechanical Compression Reduces Chondrocyte Primary Cilia Expression In Vitro
McGlashan SR, Chowdhury TT, Joshi P, Knight MM, Poole CA and Jensen CG
MOL BIOL CELL. vol. 17
01-01-2006

Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs.
Chowdhury TT, Bader DL and Lee DA
Biorheology vol. 43 (3,4), 413-429.

DOI 10.1177/0006355x2006043003004025

01-01-2006

P140 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN FRAGMENT INDUCED UPREGULATION OF NITRIC OXIDE
Chowdhury TT, Raveenthiran SP, Bader DL and Lee DA
Osteoarthritis and Cartilage, Elsevier vol. 14

DOI 10.1016/s1063-4584(07)60592-5

01-01-2006

2005

Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL and Lee DA
Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 251-252.
01-12-2005

Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs
Chowdhury TT, Appleby RN, Salter DA, Bader DL and Lee DA
Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 545-546.
01-12-2005

Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL and Lee DA
European Cells and Materials vol. 10 (SUPPL.2)
01-07-2005

Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs
Catuogno C, Chowdhury TT, Bader DL and Lee DA
European Cells and Materials vol. 10 (SUPPL.2)
01-07-2005

Dynamic compression counteracts IL-1 beta-induced iNOS and COX-2 activity in human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL and Lee AA
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 86 (3), A33-A34.
01-06-2005

Integrin-mediated mechanotransduction in IL-1 beta-stimulated chondrocytes
Appleby RN, Chowdhury TT, Salter DM, Bader DL and Lee DA
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 86 (3), A38-A39.
01-06-2005

British Society for Matrix Biology Autumn Meeting Joint with the UK Tissue & Cell Engineering Society, University of Bristol, UK

International Journal of Experimental Pathology, Wiley vol. 86 (3), a1-a56.

DOI 10.1111/j.0959-9673.2005.00426.x

24-05-2005

2004

Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes.
Chowdhury TT, Salter DM, Bader DL and Lee DA
Biochem Biophys Res Commun vol. 318 (4), 873-881.

DOI 10.1016/j.bbrc.2004.04.107

11-06-2004

Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels.
Bryant SJ, Chowdhury TT, Lee DA, Bader DL and Anseth KS
Ann Biomed Eng vol. 32 (3), 407-417.

DOI 10.1023/b:abme.0000017535.00602.ca

01-03-2004

Dynamic compression counteracts IL-1 beta-induced iNOS and COX-2 activity in human chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL and Lee DA
OSTEOARTHRITIS AND CARTILAGE. vol. 12, S19-S19.
01-01-2004

Integrin-mediated mechanotransduction in IL-1β stimulated chondrocytes
Chowdhury TT, Appleby RN, Salter DM, Bader DL and Lee DA
OSTEOARTHRITIS AND CARTILAGE. vol. 12, S102-S102.
01-01-2004

alpha 5 beta 1 integrin mediates mechanotransduction processes in TGF-beta stimulated human chondrocytes seeded in agarose constructs and subjected to dynamic compression.
Chowdhry TT, Salter DM, Bader DL and LEE DA
50th Annual Meeting of the Orthopaedic Research Society. vol. 29, 338-338.
01-01-2004

Combined anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated bovine chondrocytes cultured in agarose constructs.
Chowdhury TT, Bader DL and LEE DA
50th Annual Meeting of the Orthopaedic Research Society. vol. 29, 144-144.
01-01-2004

2003

Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression.
Chowdhury TT, Bader DL, Shelton JC and Lee DA
Arch Biochem Biophys vol. 417 (1), 105-111.

DOI 10.1016/s0003-9861(03)00340-0

01-09-2003

Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs.
Chowdhury TT, Bader DL and Lee DA
Osteoarthritis Cartilage vol. 11 (9), 688-696.

DOI 10.1016/s1063-4584(03)00149-3

01-09-2003

alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta3-stimulated human chondrocytes seeded in agarose constructs and subjected to dynamic compression.
Chowdhury TT, LEE DA, Salter DM, Shelton JC and Bader DL
ETES. vol. 9 (4), 792-792.
01-01-2003

Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs.
Chowdhury TT, Shelton JC, Bader DL and LEE DA
Internat. J. Artificial Organs vol. 26 (9), 858-858.
01-01-2003

alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression.
Chowdhury TT, LEE DA, Salter DM, Shelton JC and Bader DL
Osteoarthritis Cartilage vol. 11 (Suppl 1), S2-S3.
01-01-2003

2002

An in vitro investigation of cartilage mechanotransduction
Lee DA, Chowdhury TT, Roberts SR, Knight MM and Bader DL
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS. vol. 25 (7), 617-618.

DOI 10.1177/039139880202500733

01-07-2002

2001

Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1beta-stimulated chondrocytes cultured in agarose constructs.
Chowdhury TT, Bader DL and Lee DA
Biochem Biophys Res Commun vol. 285 (5), 1168-1174.

DOI 10.1006/bbrc.2001.5311

03-08-2001

Dynamic compression influences the synthesis of nitric oxide by IL-1beta stimulated chondrocyte sub-populations cultured in agarose constructs.
Chowdhury T, Bader DL and LEE DA
47th Annual Meeting, Orthopaedic Research Society San Francisco, California 25 Feb 2001 - 28 Feb 2001. vol. 26, 604-604.
01-01-2001

2000

Dynamic compression inhibits the synthesis of nitric oxide by IL-1β stimulated chondrocytes cultured in agarose constructs
Chowdhury TT, Bader DL and Lee DA
Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling
01-12-2000

Grants

Grants of specific relevance to the Centre for Bioengineering

Mechanisms underlying preterm birth in women with HIV in rural Zimbabwe
Andrew Prendergast, Ruairi Robertson, Melanie Smuk, Claire Bourke, Nikolaos Donos, Robert Allaker, Abish Stephen, Conrad Bessant, Stefaan Verbruggen and Tina Chowdhury
£1,142,315 MRC Medical Research Council
01-05-2024 - 30-04-2027

Extreme heat and preterm birth in rural Zimbabwe
Andrew Prendergast, Andrew Russell, Melanie Smuk, Tina Chowdhury and Stamatina Iliodromiti
£460,148 Wellcome Trust
01-10-2023 - 30-09-2028

Tommy’s National Preterm Birth Research Centre
Stamatina Iliodromiti, Tina Chowdhury and Steven Thornton
£432,791 Tommy's
01-04-2023 - 31-03-2028

Engineering the fetal membranes
Tina Chowdhury
£40,000 Prenatal Charity UCL EGA INSTITUTE FOR WOMEN’S HEALTH
01-12-2018 - 01-10-2028

Engineer the story
Tina Chowdhury
£16,890 AHRC Arts and Humanities Research Council
29-01-2021 - 31-07-2021

Engineering the fetal membranes with bioinspired materials- linked to WT 560845
Tina Chowdhury
£18,000 Rosetrees Trust
01-12-2018 - 31-03-2022

Healing the Fetal Membranes after Latrogenic PPROM
Tina Chowdhury
£176,950 Great Ormond Street Hospital Children's Charity
01-02-2018 - 05-03-2022

CASE Studentship: Wesleigh Dawsmith
Tina Chowdhury
£25,394 NPL MANAGEMENT LIMITED
01-10-2016 - 30-09-2020

PhD Studentship: James Taylor
Tina Chowdhury
£24,816 Rosetrees Trust
01-10-2015 - 30-09-2018