Dr Elisabeth Busch-Nentwich

Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy
Töpf A, Cox D, Zaharieva IT, Di Leo V, Sarparanta J, Jonson PH, Sealy IM, Smolnikov A, White RJ, Vihola A, Savarese M, Merteroglu M, Wali N, Laricchia KM, Venturini C, Vroling B, Stenton SL, Cummings BB, Harris E, Marini-Bettolo C, et al.
Nature Genetics, Springer Nature vol. 56 (3), 395-407.  
01-03-2024

Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri
Torraca V, White RJ, Sealy IM, Mazon-Moya M, Duggan G, Willis A, Busch-Nentwich EM and Mostowy S
Disease Models & Mechanisms, The Company of Biologists vol. 17 (1) 
01-01-2024

Selenoprotein deficiency disorder predisposes to aortic aneurysm formation
Schoenmakers E, Marelli F, Jørgensen HF, Visser WE, Moran C, Groeneweg S, Avalos C, Jurgens SJ, Figg N, Finigan A, Wali N, Agostini M, Wardle-Jones H, Lyons G, Rusk R, Gopalan D, Twiss P, Visser JJ, Goddard M, Nashef SAM, et al.
Nature Communications, Springer Nature vol. 14 (1), 7994-7994.  
02-12-2023

Gaucher disease protects against tuberculosis
Fan J, Hale VL, Lelieveld LT, Whitworth LJ, Busch-Nentwich EM, Troll M, Edelstein PH, Cox TM, Roca FJ, Aerts JMFG and Ramakrishnan L
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 120 (7), e2217673120-e2217673120.  
06-02-2023

P38 Mediates Tumor Suppression through Reduced Autophagy and Actin Cytoskeleton Changes in NRAS-Mutant Melanoma
Banik I, Ghosh A, Beebe E, Burja B, Frank Bertoncelj M, Dooley CM, Markkanen E, Dummer R, Busch-Nentwich EM and Levesque MP
Cancers, Mdpi vol. 15 (3), 877-877.  
31-01-2023

Conserved roles for Hnf4 family transcription factors in zebrafish development and intestinal function
Heppert JK, Lickwar CR, Tillman MC, Davis BR, Davison JM, Lu H-Y, Chen W, Busch-Nentwich EM, Corcoran DL and Rawls JF
Genetics, Oxford University Press (Oup) vol. 222 (4), iyac133-iyac133.  
11-10-2022

mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity
Pagán AJ, Lee LJ, Edwards-Hicks J, Moens CB, Tobin DM, Busch-Nentwich EM, Pearce EL and Ramakrishnan L
Cell, Elsevier vol. 185 (20), 3720-3738.e13.  
01-09-2022

Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish
Tuschl K, White RJ, Trivedi C, Valdivia LE, Niklaus S, Bianco IH, Dadswell C, González-Méndez R, Sealy IM, Neuhauss SCF, Houart C, Rihel J, Wilson SW and Busch-Nentwich EM
Disease Models and Mechanisms, The Company of Biologists vol. 15 (6) 
15-06-2022

Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants
White RJ, Mackay E, Wilson SW and Busch-Nentwich EM
Elife, Elife Sciences Publications vol. 11 
17-02-2022

Ankk1 Loss of Function Disrupts Dopaminergic Pathways in Zebrafish
Leggieri A, García-González J, Torres-Perez JV, Havelange W, Hosseinian S, Mech AM, Keatinge M, Busch-Nentwich EM and Brennan CH
Frontiers in Neuroscience, Frontiers vol. 16 
08-02-2022

Translational relevance of forward genetic screens in animal models for the study of psychiatric disease
Sheardown E, Mech AM, Petrazzini MEM, Leggieri A, Gidziela A, Hosseinian S, Sealy IM, Torres-Perez JV, Busch-Nentwich EM, Malanchini M and Brennan CH
Neuroscience and Biobehavioral Reviews, Elsevier vol. 135 
04-02-2022

Behavioral and Gene Regulatory Responses to Developmental Drug Exposures in Zebrafish
Mech AM, Merteroglu M, Sealy IM, Teh M-T, White RJ, Havelange W, Brennan CH and Busch-Nentwich EM
Frontiers in Psychiatry, Frontiers vol. 12 
10-01-2022

Total Nucleic Acid Extraction from Single Zebrafish Embryos for Genotyping and RNA-seq
Wali N, Merteroglu M, White RJ and Busch-Nentwich EM
Bio-Protocol, Bio-Protocol vol. 12 (1) 
05-01-2022