Dr Paul J. Hurd

Annelid methylomes reveal ancestral developmental and aging-associated epigenetic erosion across Bilateria
Guynes K, Sarre LA, Carrillo-Baltodano AM, Davies BE, Xu L, Liang Y, Martín-Zamora FM, Hurd PJ, de Mendoza A and Martín-Durán JM
Genome Biology, Springer Nature vol. 25 (1), 204-204.  
01-08-2024

The PWWP domain and the evolution of unique DNA methylation toolkits in Hymenoptera
Kucharski R, Ellis N, Jurkowski TP, Hurd PJ and Maleszka R
Iscience, Cell Press vol. 26 (11) 
17-11-2023

Chromatin accessibility-based characterisation of brain gene regulatory networks in three distinct honey bee polyphenisms.
Lowe R, Wojciechowski M, Ellis N and Hurd PJ
Nucleic Acids Research, Oxford University Press 
04-11-2022

Novel structure in the nuclei of honey bee brain neurons revealed by immunostaining
Hurd PJ, Grübel K, Wojciechowski M, Maleszka R and Rössler W
Scientific Reports, Nature Publishing Group vol. 11 (1) 
01-12-2021

Dataset of the next-generation sequencing of variable 16S rRNA from bacteria and ITS2 regions from fungi and plants derived from honeybees kept under anthropogenic landscapes
Gancarz M, Hurd PJ, Latoch P, Polaszek A, Michalska-Madej J, Grochowalski Ł, Strapagiel D, Gnat S, Załuski D, Rusinek R, Starosta AL, Krutmuang P, Hernández RM, Pascual MH and Ptaszyńska AA
Data in Brief, Elsevier vol. 36 
02-04-2021

Amplicon Sequencing of Variable 16S rRNA from Bacteria and ITS2 Regions from Fungi and Plants, Reveals Honeybee Susceptibility to Diseases Results from Their Forage Availability under Anthropogenic Landscapes
Ptaszyńska AA, Latoch P, Hurd PJ, Polaszek A, Michalska-Madej J, Grochowalski Ł, Strapagiel D, Gnat S, Załuski D, Gancarz M, Rusinek R, Krutmuang P, Hernández RM, Pascual MH and Starosta AL
Pathogens, Mdpi vol. 10 (3) 
22-03-2021

Phenotypic responses to temperature in the ciliate Tetrahymena thermophila
Weber de Melo V, Lowe R, Hurd PJ and Petchey OL
Ecology and Evolution, Wiley 
01-07-2020

Acute social isolation alters neurogenomic state in songbird forebrain.
George JM, Bell ZW, Condliffe D, Dohrer K, Abaurrea T, Spencer K, Leitão A, Gahr M, Hurd PJ and Clayton DF
Proc Natl Acad Sci U S A 
22-07-2019

Phenotypically distinct female castes in honey bees are defined by alternative chromatin states during larval development
WOJCIECHOWSKI M, LOWE R, Maleszka J, CONN D, Maleszka R and HURD PJ
Genome Research, Cold Spring Harbor Laboratory Press 
22-08-2018

Changes in the bioelement content of summer and winter western honeybees (Apis mellifera) induced by Nosema ceranae infection
Ptaszyńska AA, Gancarz M, Hurd PJ, Borsuk G, Wiącek D, Nawrocka A, Strachecka A, Załuski D and Paleolog J
Plos One, Public Library of Science (Plos) vol. 13 (7) 
25-07-2018

Binding loci of RelA-containing nuclear factor-kappaB dimers in promoter regions of PHM1-31 myometrial smooth muscle cells.
Cookson VJ, Waite SL, Heath PR, Hurd PJ, Gandhi SV and Chapman NR
Mol Hum Reprod vol. 21 (11), 865-883.  
01-11-2015

Arginine methylation and citrullination of splicing factor proline- and glutamine-rich (SFPQ/PSF) regulates its association with mRNA.
Snijders AP, Hautbergue GM, Bloom A, Williamson JC, Minshull TC, Phillips HL, Mihaylov SR, Gjerde DT, Hornby DP, Wilson SA, Hurd PJ and Dickman MJ
Rna vol. 21 (3), 347-359.  
01-03-2015

S6 kinase 2 is bound to chromatin-nuclear matrix cellular fractions and is able to phosphorylate histone H3 at threonine 45 in vitro and in vivo.
Ismail HMS, Hurd PJ, Khalil MIM, Kouzarides T, Bannister A and Gout I
J Cell Biochem vol. 115 (6), 1048-1062.  
01-06-2014

Epigenetic mechanisms in development and disease.
Murrell A, Hurd PJ and Wood IC
Biochem Soc Trans vol. 41 (3), 697-699.  
01-06-2013

Inactive or moderately active human promoters are enriched for inter-individual epialleles.
Gemma C, Ramagopalan SV, Down TA, Beyan H, Hawa MI, Holland ML, Hurd PJ, Giovannoni G, Leslie RD, Ebers GC and Rakyan VK
Genome Biol vol. 14 (5) 
25-05-2013

Extensive histone post-translational modification in honey bees.
Dickman MJ, Kucharski R, Maleszka R and Hurd PJ
Insect Biochem Mol Biol vol. 43 (2), 125-137.  
01-02-2013

Meeting preview
Murrell A, Hurd P and Wood I
The Biochemist, Portland Press vol. 34 (5) 
01-10-2012

The era of epigenetics.
Hurd PJ
Brief Funct Genomics vol. 9 (5-6), 425-428.  
01-12-2010

Systems biology for ecology. From molecules to ecosystems
Purdy KJ, Hurd PJ, Moya-Laraño J, Trimmer M, Oakley BB and Woodward G
 
30-11-2010

Systems Biology for Ecology: From Molecules to Ecosystems
Purdy KJ, Hurd PJ, Moya-Larano J, Trimmer M, Oakley BB and Woodward G
Adv Ecol Res vol. 43, 87-149.  
01-01-2010

Chapter 3 Systems Biology for Ecology From Molecules to Ecosystems
Purdy KJ, Hurd PJ, Moya-Laraño J, Trimmer M, Oakley BB and Woodward G
In Integrative Ecology: From Molecules to Ecosystems, Elsevier 87-149.  
01-01-2010

Phosphorylation of histone H3 Thr-45 is linked to apoptosis.
Hurd PJ, Bannister AJ, Halls K, Dawson MA, Vermeulen M, Olsen JV, Ismail H, Somers J, Mann M, Owen-Hughes T, Gout I and Kouzarides T
J Biol Chem vol. 284 (24), 16575-16583.  
12-06-2009

Advantages of next-generation sequencing versus the microarray in epigenetic research.
Hurd PJ and Nelson CJ
Brief Funct Genomic Proteomic vol. 8 (3), 174-183.  
01-05-2009

Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus
Smith AE, Hurd PJ, Bannister AJ, Kouzarides T and Ford KG
J Biol Chem vol. 283 (15), 9878-9885.  
11-04-2008

DNMT1 interacts with the developmental transcriptional repressor HESX1.
Sajedi E, Gaston-Massuet C, Andoniadou CL, Signore M, Hurd PJ, Dattani M and Martinez-Barbera JP
Biochim Biophys Acta vol. 1783 (1), 131-143.  
01-01-2008

Directed de novo DNA methylation of a genomic locus leads to heritable transcriptional repression
Ford KG, Hurd PJ, Bannister AJ, Kouzarides T and Smith AE
BLOOD. vol. 110 (11), 108A-108A.  
16-11-2007

Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos
Torres-Padilla ME, Bannister AJ, Hurd PJ, Kouzarides T and Zernicka-Goetz M
Int J Dev Biol vol. 50 (5), 455-461.  
01-01-2006

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase.
Fuks F, Hurd PJ, Deplus R and Kouzarides T
Nucleic Acids Res vol. 31 (9), 2305-2312.  
01-05-2003

The Methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
Fuks F, Hurd PJ, Wolf D, Nan XS, Bird AP and Kouzarides T
J Biol Chem vol. 278 (6), 4035-4040.  
07-02-2003

Characterisation of site-biased DNA methyltransferases: specificity, affinity and subsite relationships
McNamara AR, Hurd PJ, Smith AEF and Ford KG
Nucleic Acids Res vol. 30 (17), 3818-3830.  
01-09-2002

Zebularine: a novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases.
Zhou L, Cheng X, Connolly BA, Dickman MJ, Hurd PJ and Hornby DP
J Mol Biol vol. 321 (4), 591-599.  
23-08-2002

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone.
HURD PJ, Whitmarsh AJ, Baldwin GS, Kelly SM, Waltho JP, Price NC, Connolly BA and Hornby DP
Journal of Molecular Biology vol. 286 (2), 389-401.  
01-01-1999