Sensing and Imaging

Our multidisciplinary team is focusing on the development of novel platforms for sensing and imaging of biological systems. Our strength lies in the combination of cutting-edge research in both, biomedical engineering and materials science. This has enabled significant advancements in the development of instrumentation and devices, which would not have been possible without the unique combination of skills available in the School of Engineering and Materials Science.  

Researchers within the Centre are studying and developing a diverse range of sensors and imaging modalities. Some of the highlights are: 

  • Photoelectrochemical imaging (PEI) capable of mapping cell signalling with micron resolution has been developed for cellular analysis. Recent innovations include the combination of PEI with scanning ion conductance microscopy. We are currently focusing on the adaptation of this technology for 3D imaging and its miniaturisation for in-vivo use.  

  • Optical fibre imaging technology has enabled the development of ultrathin, high-resolution micro-endoscopes. This work is currently commercially exploited via a spin-out company, Pryfiber Ltd. 

  • Wearable optical and ultrasound sensors are being developed for preclinical testing or next-generation homecare devices. 

  • Implantable arrays of multifunctional high-resolution biosensors are being developed for the monitoring of tumour state and combining these arrays with predictive in vitro models to facilitate real-time data output. 

  • Machine learning and artificial intelligence assisted sensing and imaging in healthcare. 

Flexible implantable array of biosensors
Flexible implantable array of biosensors 
Photoelectrochemical image of a single cell Photoelectrochemical image of a single cell