Prof Conrad Bessant
Professor of Bioinformatics
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
data science, computational biology, bioinformatics, artificial intelligence, drug discovery
Interests
Conrad Bessant has ~25 years’ experience of data science, tackling research questions in analytical chemistry, biomolecular science, and qualitative healthcare studies.His overarching research interest is the automation of scientific discovery in the biomedical domain. While some aspects of biomedical research such as data acquisition and routine analysis are already commonly automated, fundamental research activities such as hypothesis generation, identification of relevant datasets and interpretation of results still require extensive input from human experts. This is becoming increasingly intractable as available datasets grow in size and complexity – innovative solutions to automate the process are needed.
Technologies being used by Conrad’s research group to automate the scientific discovery process include machine learning, relational modelling, network science and Bayesian inference.
Conrad is based in QMUL’s Digital Environment Research Institute. He leads QMUL’s MSc Bioinformatics programme and is the academic lead of the UKRI AI for Drug Discovery Doctoral Training Programme.
Publications
2023
Comparison of multiple modalities for drug response prediction with learning curves using neural networks and XGBoostBranson N, Cutillas PR and Bessant C
Bioinformatics Advances, Oxford University Press (Oup) vol. 4 (1)
23-12-2023
Automated and reproducible cell identification in mass cytometry using neural networksSaihi H, Bessant C and Alazawi W
Briefings in Bioinformatics, Oxford University Press
02-11-2023
Inferring Compensatory Kinase Networks in Yeast using PrologElder GA and Bessant C
Electronic Proceedings in Theoretical Computer Science, Open Publishing Association vol. 385, 260-273.
12-09-2023
Community detection in empirical kinase networks identifies new potential members of signalling pathwaysDe Los Angeles Colomina Basanta C, Bazzi M, Hijazi M, Bessant C and Cutillas PR
Plos Computational Biology, Public Library of Science (Plos) vol. 19 (6)
23-06-2023
CO51 Understanding the Lived Experience of Patients By Mining Online Health BoardsBessant C, Abdollahyan M and Smeraldi F
Value in Health, Elsevier vol. 26 (6), s23-s24.
01-06-2023
Deriving Meaningful Aspects of Health Related to Physical Activity in Chronic Disease: Concept Elicitation Using Machine Learning–Assisted Coding of Online Patient ConversationsByrom B, Bessant C, Smeraldi F, Abdollahyan M, Bridges Y, Chowdhury M and Tahsin A
Value in Health, Elsevier vol. 26 (7), 1057-1066.
16-02-2023
2022
PCR3 Assessing Concept Saturation and Sample Representativeness When Using Social Media Data to Inform Concept Elicitation StudiesBessant C, Bridges Y, Chowdhury M, Tahsin A, Abdollahyan M, Smeraldi F and Byrom B
Value in Health, Elsevier vol. 25 (12)
01-12-2022
Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver diseaseWaller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn W-K, Bessant C and Alazawi W
Clinical and Molecular Hepatology, The Korean Association For The Study of The Liver vol. 29 (2), 417-432.
21-11-2022
POSB338 Identification of Meaningful Aspects of Physical Activity: Concept Elicitation By AI-Assisted Coding of Online Patient ConversationsBridges Y, Chowdhury M, Tahsin A, Bessant C, Abdollahyan M, Smeraldi F and Byrom B
Value in Health, Elsevier vol. 25 (1)
01-01-2022
2021
Analysis of mental and physical disorders associated with COVID-19 in online health forums: a natural language processing studyPatel R, Smeraldi F, Abdollahyan M, Irving J and Bessant C
Bmj Open, Bmj vol. 11 (11)
01-11-2021
2020
Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritisGomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C and Dalli J
Nature Communications, Springer Nature vol. 11 (1)
27-10-2020
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancerGadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C
Npj Breast Cancer, Nature Research (Part of Springer Nature) vol. 6 (1)
21-08-2020
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer.Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C
Npj Breast Cancer vol. 6 (1)
21-08-2020
Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiringHijazi M, Smith R, Rajeeve V, Bessant C and Cutillas PR
Nature Biotechnology, Nature Research
20-01-2020
Investigating Comorbidity of Mental and Physical Disorders in Online Health ForumsAbdollahyan M, Smeraldi F, Patel R and Bessant C
Proceedings of the 3rd International Conference on Applications of Intelligent Systems., 1-5.
07-01-2020
2019
Abstract C088: Chemical phosphoproteomics systematically identifies circuitries of kinase networks in cancer cells and predicts their response to kinase inhibitorsCutillas PR, Hijazi M, Smith R, Bessant C and Britton D
Molecular Cancer Therapeutics. vol. 18 (12_Supplement), c088-c088.
01-12-2019
2018
THU0052 A circulating protein signature correlates with synovial pathotypes in rheumatoid arthritis patientsRuiz-Romero C, Picchi F, Fernández-Puente P, González-Rodríguez L, Hands R, Calamia V, Camacho-Encina M, Bessant C, Pitzalis C and Blanco FJ
THURSDAY, 14 JUNE 2018. vol. 77 (Suppl 2)
01-06-2018
SAT0074 Identification of a protein panel useful for the prediction of response to methotrexate in rheumatoid arthritis patientsRuiz-Romero C, Picchi F, González-Rodríguez L, Fernández-Puente P, Hands R, Calamia V, Camacho-Encina M, Bessant C, Pitzalis C and Blanco FJ
Saturday, 16 JUNE 2018. vol. 77 (Suppl 2)
01-06-2018
High throughput discovery of protein variants using proteomics informed by transcriptomicsSaha S, Matthews DA and Bessant C
Nucleic Acids Research, Oxford University Press (Oup) vol. 46 (10)
30-04-2018
Visualising the topological structure of health-elated message board user networksAbdollahyan M, Mondragón RJ, Bessant C and Smeraldi F
Frontiers in Artificial Intelligence and Applications. vol. 310, 274-279.
01-01-2018
Identification of a Panel of Circulating Proteins Associated to Synovial Pathotypes in Early Rheumatoid Arthritis PatientsRuiz-Romero C, Picchi F, Fernandez P, Gonzalez L, Hands R, Calamia V, Camacho M, Bessant C, Pitzalis C and Blanco FJ
ARTHRITIS & RHEUMATOLOGY. vol. 70
01-01-2018
Identification of a Protein Profile Useful to Predict Response to Methotrexate in Early Rheumatoid Arthritis PatientsRuiz-Romero C, Picchi F, Gonzalez L, Hands R, Calamia V, Fernandez P, Camacho M, Paz R, Bessant C, Pitzalis C and Blanco FJ
ARTHRITIS & RHEUMATOLOGY. vol. 70
01-01-2018
2017
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers.Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, et al.
Cancer Discov
01-12-2017
PITDB: a database of translated genomic elementsSAHA S, Chatzimichali E, Matthews D and Bessant C
Nucleic Acids Research, Oxford University Press
09-10-2017
Abstract 5558: Deconstruction of a human tumor microenvironmentBalkwill FR, Pearce OM, Delaine-Smith R, Maniati E, Nichols S, Wang J, Bessant C and Knight M
Cancer Research. vol. 77 (13_Supplement), 5558-5558.
01-07-2017
Proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in Aedes aegypti.Maringer K, Yousuf A, Heesom KJ, Fan J, Lee D, Fernandez-Sesma A, Bessant C, Matthews DA and Davidson AD
Bmc Genomics vol. 18 (1), 101-101.
19-01-2017
2016
Chapter 16 Proteomics Informed by TranscriptomicsSaha S, Matthews D and Bessant C
In Proteome Informatics, Royal Society of Chemistry (Rsc) 385-405.
15-11-2016
Chapter 1 Introduction to Proteome InformaticsBessant C
In Proteome Informatics, Royal Society of Chemistry (Rsc) 1-14.
15-11-2016
Enteral feeding reduces metabolic activity of the intestinal microbiome in Crohn’s disease: an observational studyWalton C, Montoya MPB, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C, Naylor SJ and Hunter JO
European Journal of Clinical Nutrition, Nature Publishing Group: Open Access Hybrid Model Option B vol. 70, 1052-1056.
11-05-2016
Evaluation of gas chromatography mass spectrometry and pattern recognition for the identification of bladder cancer from urine headspaceCauchi M, Weber CM, Bolt BJ, Spratt PB, Bessant C, Turner DC, Willis CM, Britton LE, Turner C and Morgan G
Analytical Methods, Royal Society of Chemistry (Rsc) vol. 8 (20), 4037-4046.
01-01-2016
Ensemble-based support vector machine classifiers as an efficient tool for quality assessment of beef fillets from electronic nose dataMohareb F, Papadopoulou O, Panagou E, Nychas G-J and Bessant C
Analytical Methods, Royal Society of Chemistry (Rsc) vol. 8 (18), 3711-3721.
01-01-2016
2015
Novel application of heuristic optimisation enables the creation and thorough evaluation of robust support vector machine ensembles for machine learning applicationsChatzimichali EA and Bessant C
Metabolomics, Springer Nature vol. 12 (1)
21-11-2015
The mzqLibrary - An open source Java library supporting the HUPO-PSI quantitative proteomics standardQi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR
Proteomics vol. 15 (18), 3152-3162.
01-09-2015
Galaxy Integrated Omics: Web-based Standards-Compliant Workflows for Proteomics Informed by Transcriptomics*[S]Fan J, Saha S, Barker G, Heesom KJ, Ghali F, Jones AR, Matthews DA and Bessant C
Molecular & Cellular Proteomics, Elsevier vol. 14 (11), 3087-3093.
12-08-2015
The mzqLibrary – An open source Java library supporting the HUPO‐PSI quantitative proteomics standardQi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR
Proteomics, Wiley vol. 15 (18), 3152-3162.
14-07-2015
Comparison of GC-MS, HPLC-MS and SIFT-MS in conjunction with multivariate classification for the diagnosis of Crohn's disease in urineCauchi M, Fowler DP, Walton C, Turner C, Waring RH, Ramsden DB, Hunter JO, Teale P, Cole JA and Bessant C
Analytical Methods, Royal Society of Chemistry (Rsc) vol. 7 (19), 8379-8385.
01-01-2015
2014
A tutorial for software development in quantitative proteomics using PSI standard formats.Gonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR
Biochim Biophys Acta vol. 1844 (1 Pt A), 88-97.
01-01-2014
Current trends in machine-learning methods applied to spectroscopic cancer diagnosisSattlecker M, Stone N and Bessant C
Trac Trends in Analytical Chemistry, Elsevier/Science Direct vol. 59, 17-25.
01-01-2014
Application of gas chromatography mass spectrometry (GC–MS) in conjunction with multivariate classification for the diagnosis of gastrointestinal diseasesCauchi M, Fowler DP, Walton C, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH and others
Metabolomics, Springer Us vol. 10 (6), 1113-1120.
01-01-2014
A tutorial for software development in quantitative proteomics using PSI standard formatsGonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR
Biochimica Et Biophysica Acta-Proteins and Proteomics vol. 1844 (1), 88-97.
01-01-2014
2013
Analysis of volatile organic compounds of bacterial origin in chronic gastrointestinal diseases.Walton C, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C and Hunter JO
Inflamm Bowel Dis vol. 19 (10), 2069-2078.
01-09-2013
The mzQuantML data standard for mass spectrometry-based quantitative studies in proteomics.Walzer M, Qi D, Mayer G, Uszkoreit J, Eisenacher M, Sachsenberg T, Gonzalez-Galarza FF, Fan J, Bessant C, Deutsch EW, Reisinger F, Vizcaíno JA, Medina-Aunon JA, Albar JP, Kohlbacher O and Jones AR
Mol Cell Proteomics vol. 12 (8), 2332-2340.
01-08-2013
Computational approaches to selected reaction monitoring assay design.Bessant C and Fan J
Methods Mol Biol vol. 1007, 219-235.
01-01-2013
Computational approaches to selected reaction monitoring assay designBessant C and Fan J
Methods in Molecular Biology vol. 1007, 219-235.
01-01-2013
2012
De novo derivation of proteomes from transcriptomes for transcript and protein identification.Evans VC, Barker G, Heesom KJ, Fan J, Bessant C and Matthews DA
Nat Methods vol. 9 (12), 1207-1211.
01-12-2012
A critical appraisal of techniques, software packages, and standards for quantitative proteomic analysis.Gonzalez-Galarza FF, Lawless C, Hubbard SJ, Fan J, Bessant C, Hermjakob H and Jones AR
Omics vol. 16 (9), 431-442.
01-09-2012
MRMaid 2.0: mining PRIDE for evidence-based SRM transitions.Fan J, Mohareb F, Bond NJ, Lilley KS and Bessant C
Omics vol. 16 (9), 483-488.
01-09-2012
Diversity and distribution of sulphate-reducing bacteria in human faeces from healthy subjects and patients with inflammatory bowel disease.Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH, Ramsden DB, Hunter JO, Cauchi M, Bessant C, Fowler DP, Walton C, Turner C and Cole JA
Fems Immunol Med Microbiol vol. 65 (1), 55-68.
01-06-2012
Colorimetric analysis of agonistic/antagonistic actions on estrogen receptor using peptide-functionalized gold nanoparticle sensorIkeno S, Sano K, Cauchi M, Takatsuji Y, Bessant C and Haruyama T
Biosensors.
17-05-2012
MRMaid: The SRM Assay Design Tool for Arabidopsis and Other Species.Fan J, Mohareb F, Jones AME and Bessant C
Front Plant Sci vol. 3
01-01-2012
2011
Application of multiple response optimization design to quantum dot-encoded microsphere bioconjugates hybridization assay.Thiollet S, Bessant C and Morgan SL
Anal Biochem vol. 414 (1), 23-30.
01-07-2011
A comparison of artificial neural networks and partial least squares modelling for the rapid detection of the microbial spoilage of beef fillets based on Fourier transform infrared spectral fingerprints.Panagou EZ, Mohareb FR, Argyri AA, Bessant CM and Nychas G-JE
Food Microbiol vol. 28 (4), 782-790.
01-06-2011
Evaluation of a gas sensor array and pattern recognition for the identification of bladder cancer from urine headspace.Weber CM, Cauchi M, Patel M, Bessant C, Turner C, Britton LE and Willis CM
Analyst vol. 136 (2), 359-364.
21-01-2011
Current perspectives and recommendations for the development of mass spectrometry methods for the determination of allergens in foods.Johnson PE, Baumgartner S, Aldick T, Bessant C, Giosafatto V, Heick J, Mamone G, O'Connor G, Poms R, Popping B, Reuter A, Ulberth F, Watson A, Monaci L and Mills ENC
J Aoac Int vol. 94 (4), 1026-1033.
01-01-2011
The quantification of pollutants in drinking water by use of artificial neural networks.Cauchi M, Bianco L and Bessant C
Nat. Comput. vol. 10, 77-90.
01-01-2011
Support vector machine ensembles for breast cancer type prediction from mid-FTIR micro-calcification spectraSattlecker M, Baker R, Stone N and Bessant C
Chemometrics and Intelligent Laboratory Systems, Elsevier vol. 107, 363-370.
01-01-2011
Assessment of robustness and transferability of classification models built for cancer diagnostics using Raman spectroscopySattlecker M, Stone N, Smith J and Bessant C
Journal of Raman Spectroscopy, Wiley Online Library vol. 42, 897-903.
01-01-2011
Data Mining for Genomics and Proteomics: Analysis of Gene and Protein Expression Data Darius M. Dziuda John Wiley and Sons, 2010, p. 327 ISBN: 978-0-470-16373-3Bessant C
Proteomics, Wiley-Vch Verlag vol. 11, 3768-3768.
01-01-2011
Experiences in Pattern Recognition for Machine OlfactionBessant C
, American Institute of Physics
01-01-2011
2010
Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis.Kolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and Reither K
J Clin Microbiol vol. 48 (11), 4235-4238.
01-11-2010
Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics.Sattlecker M, Bessant C, Smith J and Stone N
Analyst vol. 135 (5), 895-901.
01-05-2010
Free computational resources for designing selected reaction monitoring transitions.Cham Mead JA, Bianco L and Bessant C
Proteomics vol. 10 (6), 1106-1126.
01-03-2010
Linking Bistable Dynamics to Metabolic P SystemsPagliarini R, Bianco L, Manca V and Bessant C
Eighth Brainstorming Week on Membrane Computing Universidad de Sevilla, Seville, Spain 1 Feb 2010 - 5 Feb 2010., 205-218.
05-02-2010
Mining proteomic MS/MS data for MRM transitions.Chem Mead JA, Bianco L and Bessant C
Methods Mol Biol vol. 604, 187-199.
01-01-2010
MRMaid-DB: a repository of published SRM transitions.Cham JA, Bianco L, Barton C and Bessant C
J Proteome Res vol. 9 (1), 620-625.
01-01-2010
Discerning data analysis methods to clarify agonistic/antagonistic actions on the ion flux assay of ligand-gated ionotropic glutamate receptor on engineered post-synapse model cellsTetsuya H
Journal of Biosensors & Bioelectronics
01-01-2010
Tissular model/sensor seamless system for qualified analysis and its characterizationTanoue C, Asakawa H, Cauchi M, Bessant C, Ikeno S and Haruyama T
Biochemical Engineering Journal, Elsevier vol. 52, 110-115.
01-01-2010
Electronic-nose technology in diagnosis of TB patients using sputum samplesKolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and others
Journal of Clinical Microbiology, Am Soc Microbiol
01-01-2010
ABUNDANCE OF SULPHATE REDUCING BACTERIA IN INFLAMMATORY BOWEL DISEASEJia W, Griffiths L, Whitehead B, Basser SJ, Dawson C, Turner C, Bessant C, Fowler D, Walton C, Ramsden D and others
GUT BMJ PUBLISHING GROUP BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND. vol. 59, A97-A98.
01-01-2010
2009
Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers.Spooner AD, Bessant C, Turner C, Knobloch H and Chambers M
Analyst vol. 134 (9), 1922-1927.
01-09-2009
Comparison of novel decoy database designs for optimizing protein identification searches using ABRF sPRG2006 standard MS/MS data sets.Blanco L, Mead JA and Bessant C
J Proteome Res vol. 8 (4), 1782-1791.
01-04-2009
Fourier transform infrared spectroscopic studies of T-cell lymphoma, B-cell lymphoid and myeloid leukaemia cell lines.Babrah J, McCarthy K, Lush RJ, Rye AD, Bessant C and Stone N
Analyst vol. 134 (4), 763-768.
01-04-2009
MRMaid, the web-based tool for designing multiple reaction monitoring (MRM) transitions.Mead JA, Bianco L, Ottone V, Barton C, Kay RG, Lilley KS, Bond NJ and Bessant C
Mol Cell Proteomics vol. 8 (4), 696-705.
01-04-2009
Dyes assay for measuring physicochemical parameters.Moczko E, Meglinski IV, Bessant C and Piletsky SA
Anal Chem vol. 81 (6), 2311-2316.
15-03-2009
Recent developments in public proteomic MS repositories and pipelines.Mead JA, Bianco L and Bessant C
Proteomics vol. 9 (4), 861-881.
01-02-2009
Development of a Workflow for Protein Sequence Analysis Based on the Taverna Workbench Software.Monteiro MB, Pintado ME, Malcata FX, Bessant C and Moreira PR
IWANN (2). vol. 5518, 1118-1124. Editors: Omatu S, Rocha M, Bravo J, Riverola FF, Corchado E, Bustillo A and Corchado JM.
01-01-2009
Chemometric profiling of pre-climacteric Sri Lankan mango fruit (< i> Mangifera indica L.)Thanaraj T, Terry LA and Bessant C
Food Chemistry, Elsevier vol. 112, 786-794.
01-01-2009
Protein folding location determines binding of manganese versus copperTottey S, Robinson N, Waldron K, Firbank S and Bessant C
Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology, Pergamon vol. 153, S159-S159.
01-01-2009
2008
Metalloprotein metal pools: identification and quantification by coupling native and non-native separations through principal component analysisRobinson N, Waldron K, Tottey S and Bessant C
Protocol Exchange, Springer Nature
12-11-2008
Protein-folding location can regulate manganese-binding versus copper- or zinc-binding.Tottey S, Waldron KJ, Firbank SJ, Reale B, Bessant C, Sato K, Cheek TR, Gray J, Banfield MJ, Dennison C and Robinson NJ
Nature vol. 455 (7216), 1138-1142.
23-10-2008
OSPACS: Ultrasound image management system.Stott W, Ryan A, Jacobs IJ, Menon U, Bessant C and Jones C
Source Code Biol Med vol. 3
20-06-2008
Simultaneous Quantitative Determination of Cadmium, Lead, and Copper on Carbon-Ink Screen-Printed Electrodes by Differential Pulse Anodic Stripping Voltammetry and Partial Least Squares RegressionCauchi M, Bessant C and Setford S
Electroanalysis, Wiley Online Library vol. 20, 2571-2577.
01-01-2008
Using Bioinformatics to Increase Speed and Reduce Uncertainty in Protein Biomarker DiscoveryMead J, Bianco L and Bessant C
Cranfield Multi-Strand Conference: Creating Wealth Through Research and Innovation vol. 6, 118-118.
01-01-2008
2007
Public proteomic MS repositories and pipelines: available tools and biological applications.Mead JA, Shadforth IP and Bessant C
Proteomics vol. 7 (16), 2769-2786.
01-08-2007
FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell linesBabrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N
Diagnostic Optical Spectroscopy in Biomedicine IV. vol. 6628
05-07-2007
A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray Data.Kumuthini J, Jouffe L and Bessant C
BIRD. vol. 4414, 28-37. Editors: Hochreiter S and Wagner R.
01-01-2007
Proposed minimum reporting standards for data analysis in metabolomicsGoodacre R, Broadhurst D, Smilde AK, Kristal BS, Baker JD, Beger R, Bessant C, Connor S, Capuani G, Craig A and others
Metabolomics, Springer Us vol. 3, 231-241.
01-01-2007
Microarray Analysis Software and its ApplicationsBessant C
Handbook of Biosensors and Biochips, John Wiley & Sons, Ltd
01-01-2007
FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines [6628-28]Babrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N
Proceedings-Spie The International Society For Optical Engineering, International Society For Optical Engineering; 1999 vol. 6628, 6628-6628.
01-01-2007
FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell linesBabrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N
European Conference on Biomedical Optics International Society for Optics and Photonics., 66280R-66280R.
01-01-2007
Gene regulatory network of human adipocyte differentiationKumuthini J, Bessant C, Wilson P and Crowther D
Bmc Systems Biology, Biomed Central Ltd vol. 1, P57-P57.
01-01-2007
Session 1-Microarray and Systems Biology I (Networks)-A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray DataKumuthini J, Jouffe L and Bessant C
Lecture Notes in Computer Science vol. 4414, 28-28.
01-01-2007
Fourier transform infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell linesBabrah J, Lush R, Rye A, McCarthy K, Bessant C and Stone N
BRITISH JOURNAL OF HAEMATOLOGY BLACKWELL PUBLISHING 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND. vol. 137, 4-4.
01-01-2007
2006
Genome annotating proteomics pipelines: available tools.Shadforth I and Bessant C
Expert Rev Proteomics vol. 3 (6), 621-629.
01-12-2006
GAPP: a fully automated software for the confident identification of human peptides from tandem mass spectra.Shadforth I, Xu W, Crowther D and Bessant C
J Proteome Res vol. 5 (10), 2849-2852.
01-10-2006
Evaluation of a genomics platform for cross-species transcriptome analysis of recombinant CHO cells.Ernst W, Trummer E, Mead J, Bessant C, Strelec H, Katinger H and Hesse F
Biotechnol J vol. 1 (6), 639-650.
01-06-2006
Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum.Fend R, Kolk AHJ, Bessant C, Buijtels P, Klatser PR and Woodman AC
J Clin Microbiol vol. 44 (6), 2039-2045.
01-06-2006
Mapping the Arabidopsis organelle proteome.Dunkley TPJ, Hester S, Shadforth IP, Runions J, Weimar T, Hanton SL, Griffin JL, Bessant C, Brandizzi F, Hawes C, Watson RB, Dupree P and Lilley KS
Proc Natl Acad Sci U S A vol. 103 (17), 6518-6523.
25-04-2006
VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDSSaini S, Bessant C, Lee-davey J and Malecha MM
22-03-2006
Quantitative proteomic approach to study subcellular localization of membrane proteins.Sadowski PG, Dunkley TPJ, Shadforth IP, Dupree P, Bessant C, Griffin JL and Lilley KS
Nat Protoc vol. 1 (4), 1778-1789.
01-01-2006
Mapping the Arabidopsis organelle proteomeLilley KS, Hawes C, Hanton SL, Dunkley TPJ, Runions J, Hester S, Weimar T, Shadforth IP, Bessant C, Dupree P and others
Proceedings of The National Academy of Sciences of The United States of America, Editor No Identificado, 6518-6523.
01-01-2006
2005
Protein and peptide identification algorithms using MS for use in high-throughput, automated pipelines.Shadforth I, Crowther D and Bessant C
Proteomics vol. 5 (16), 4082-4095.
01-11-2005
i-Tracker: for quantitative proteomics using iTRAQ.Shadforth IP, Dunkley TPJ, Lilley KS and Bessant C
Bmc Genomics vol. 6
20-10-2005
Determination of partial amino acid composition from tandem mass spectra for use in peptide identification strategies.Shadforth I, Todd K, Crowther D and Bessant C
Proteomics vol. 5 (7), 1787-1796.
01-05-2005
VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDSSAINI S, BESSANT C, LEE-DAVEY J, MALECHA M and others
07-01-2005
Confident protein identification using the average peptide score method coupled with search-specific, ab initio thresholds.Shadforth I, Dunkley T, Lilley K, Crowther D and Bessant C
Rapid Commun Mass Spectrom vol. 19 (22), 3363-3368.
01-01-2005
2004
Monitoring haemodialysis using electronic nose and chemometrics.Fend R, Bessant C, Williams AJ and Woodman AC
Biosens Bioelectron vol. 19 (12), 1581-1590.
15-07-2004
Voltammetric detection of metabolites in physiological fluidsSaini S, Bessant C, Lee-Davey J and Malecha MM
28-06-2004
Simultaneous quantification of analytes in quaternary mixtures using dual pulse staircase voltammetry and genetically optimised neural networks.Richards E, Bessant C and Saini S
Analyst vol. 129 (4), 355-358.
01-04-2004
Search-Space Reduction of a Non-Redundant Peptide Database.Shadforth I, Crowther D and Bessant C
CSB., 470-471.
01-01-2004
An Overview of Soft Computing Techniques Used in the Drug Discovery Process.Oduguwa A, Tiwari A, Roy R and Bessant C
WSC. vol. 34, 465-480. Editors: Abraham A, Baets BD, Köppen M and Nickolay B.
01-01-2004
2003
Identification of oil contaminants on polymer coated beverage cans using fluorescence spectroscopy.Malecha M, Bessant C and Saini S
Appl Spectrosc vol. 57 (8), 1042-1048.
01-08-2003
A liquid handling system for the automated acquisition of data for training, validating and testing calibration modelsRichards E, Bessant C and Saini S
Sensors and Actuators B: Chemical, Elsevier vol. 88, 149-154.
01-01-2003
Neural networks for the calibration of voltammetric dataBessant C and Richards E
Nature-Inspired Methods in Chemometrics: Genetic Algorithms and Artificial Neural Networks: Genetic Algorithms and Artificial Neural Networks, Elsevier vol. 23, 257-257.
01-01-2003
2002
DIAGNOSIS BY SENSING VOLATILE COMPONENTSSAINI S, BESSANT C, LIEDTKE C, LEIFERKUS J and others
01-11-2002
Principal components analysis for the visualisation of multidimensional chemical data acquired by scanning Raman microspectroscopy.Malecha M, Bessant C and Saini S
Analyst vol. 127 (9), 1261-1266.
01-09-2002
Multivariate data analysis in electroanalytical chemistryRichards E, Bessant C and Saini S
Electroanalysis, Wiley Online Library vol. 14, 1533-1542.
01-01-2002
Optimisation of a neural network model for calibration of voltammetric dataRichards E, Bessant C and Saini S
Chemometrics and Intelligent Laboratory Systems, Elsevier vol. 61, 35-49.
01-01-2002
Identification of oil contaminants on polymer coated beverage cans using Raman spectroscopyMalecha M, Bessant C, Perry D and Saini S
Analyst, Royal Society of Chemistry vol. 127, 297-303.
01-01-2002
2001
Simultaneous resolution of overlapping tailing peaks of Isomers using dual detector diode array liquid Chromatography electrospray mass spectrometryBrereton RG and Bessant C
Aegean Analytical Chemistry Conference.
31-12-2001
Sniffing out disease using the artificial nose.Saini S, Barr H and Bessant C
Biologist (London) vol. 48 (5), 229-233.
01-10-2001
Chemometric evaluation of synchronous scan fluorescence spectroscopy for the determination of regulatory conformance and usage history of insulation oilsBessant C, Ritchie L, Saini S, Pahlavanpour B and Wilson G
Applied Spectroscopy, Society For Applied Spectroscopy vol. 55, 840-846.
01-01-2001
2000
A ten channel fibre-optic device for distributed sensing of underground hydrocarbon leakage.Ritchie LJ, Ferguson CP, Bessant C and Saini S
J Environ Monit vol. 2 (6), 670-673.
01-12-2000
A chemometric analysis of dual pulse staircase voltammograms obtained in mixtures of ethanol, fructose and glucoseBessant C and Saini S
Journal of Electroanalytical Chemistry, Elsevier vol. 489, 76-83.
01-01-2000
1999
Simultaneous determination of ethanol, fructose, and glucose at an unmodified platinum electrode using artificial neural networksBessant C and Saini S
Analytical Chemistry, Acs Publications vol. 71, 2806-2813.
01-01-1999
Integrated processing of triply coupled diode array liquid chromatography electrospray mass spectrometric signals by chemometric methodsBrereton R and others
Analyst, Royal Society of Chemistry vol. 124, 1733-1744.
01-01-1999
1997
An object oriented approach to electroanalytical technique implementationBessant C and Saini S
Electroanalysis, Wiley Online Library vol. 9, 926-931.
01-01-1997
Grants
Grants of specific relevance to the Centre for Molecular Cell BiologyAI driven Omics Data Integration and Transfer Learning for Target and Biomarker IdentificationConrad Bessant
£127,935 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2024 - 30-09-2028
BBSRC AIDD CTP CASE Award: Syed Zayyan MasudConrad Bessant
£21,600 Nxera Pharma UK Ltd
01-10-2024 - 30-09-2028
Mechanisms underlying preterm birth in women with HIV in rural ZimbabweAndrew Prendergast, Ruairi Robertson, Melanie Smuk, Claire Bourke, Nikolaos Donos, Robert Allaker, Abish Stephen, Conrad Bessant, Stefaan Verbruggen and Tina Chowdhury
£1,142,315 MRC Medical Research Council
01-05-2024 - 30-04-2027
Martina Occhetta CTP Studentship - Exscientia FundedConrad Bessant and Emma Tjong
£8,600 EXSCIENTIA LIMITED
01-10-2023 - 30-09-2027
TG: Target identification from multiomics data using systems biology and machine learning approachesConrad Bessant
£125,917 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2023 - 30-09-2027
CTP Training Grant: Lewis PalmerConrad Bessant
£123,829 BBSRC Biotechnology and Biological Sciences Research Council
01-10-2022 - 12-11-2026
BBSRC AIDD CTP CASE Award: Lewis Palmer: “Prioritising Drug Targets in non-canonical pathways from multi-omic dataConrad Bessant
£10,400 Merck
26-09-2022 - 25-09-2026
Survey and BIOinformatic review of fluid-tissue proteomics: novel biomarkers for ALSAndrea Malaspina and Conrad Bessant
£188,946 Barts and the London Charity
01-09-2020 - 31-08-2025
Identifying regulatory nodes and vulnerablities of molecular networks using graph theory and machine learning analysis of proteomics dataPedro Rodriguez Cutillas and Conrad Bessant
£45,554 Alan Turing Institute, The
01-03-2020 - 31-01-2021
Alan Turing Institute Enrichment Placement Scheme - George ElderConrad Bessant
£1,746 Alan Turing Institute, The
01-01-2020 - 30-06-2020
Automatic Learning in Cancer Research using Artificial IntelligenceTrevor Graham and Conrad Bessant
£178,177 Alan Turing Institute, The
01-10-2018 - 31-03-2022
Bid for MRC Industrial Strategy PhD Studentship 2018Conrad Bessant
£93,462 MRC Medical Research Council
01-10-2018 - 31-03-2022