Events

Date: 4 February 2025   Time: 12:00 - 13:00     

Location: SEMS Seminar Room, 3rd floor, Engineering Building

Title:

Designing Biomaterials with Spatiotemporal Control for Tissue Engineering Applications

Abstract:

Advances in materials science, biomolecule delivery, and cell biology has enabled significant innovations within the field of tissue engineering and regenerative medicine over the past few decades. Nonetheless, minimal translation of tissue engineering-based therapeutics to the clinic has occurred. An ongoing challenge within tissue engineering is the difficulty in regenerating functional tissues with a heterogeneous structure and multiple cell types. To address this challenge, my research group integrates biomaterial design with innovative manufacturing to control stem cell behavior for tissue engineering and regenerative medicine applications. Within this area, we have focused on the following areas: 1) spatial modulation of cell instructive cues to mimic natural tissue heterogeneity, 2) temporal modulation of cell instructive cues to mimic the natural healing cascade, 3) injectable biomaterials for minimally invasive applications, and 4) immunomodulatory biomaterials to control the balance between regeneration and inflammatory signaling. In this seminar, I will specifically discuss our recent work using magnetic fields to spatially and temporally control biomaterial properties to mimic the complexity of musculoskeletal tissues.

About the speaker:

Julianne Holloway is an Associate Professor of Chemical Engineering at Arizona State University (ASU) and an associate faculty member within the Biodesign Institute's Center for Molecular Design and Biomimetics. Prior to ASU, Julianne completed her Ph.D. in Chemical Engineering at Drexel University and her postdoctoral training at the University of Pennsylvania. Julianne's research group integrates biomaterial design with innovative manufacturing to control and direct stem cell behavior for tissue engineering and regenerative medicine applications. Julianne is also committed to service and leadership, including American Institute of Chemical Engineers (AIChE) Director (2020-2023), Regenerative Biomaterials Editorial Board (current), and Science Translational Medicine Associate Scientific Advisor (2018-2019). Her significant contributions to chemical engineering have been recognized through several prestigious awards, including the AIChE 35 Under 35 Award, AIChE John C. Chen Young Professional Leadership Award, as a Journal of Biomedical Materials Research (JBMR) Emerging Scholar in Biomaterials, and the Musculoskeletal Transplant Foundation (MTF) Biologics Junior Investigator Award (1 of 5 international awardees in 2022). Additionally, she has been invited for numerous seminars and conference presentations (40+ invited talks), including at the American Chemical Society (ACS) Fall Meeting, Materials Research Society (MRS) Fall and Spring Meetings, and AIChE's Annual Meeting as a plenary speaker in the "Area 8A (Polymers) Plenary: Emerging Areas in Polymer Science and Engineering".